cis-4-Aminocyclohexanecarboxylic acid
- CAS No.
- 3685-23-2
- Chemical Name:
- cis-4-Aminocyclohexanecarboxylic acid
- Synonyms
- H-CIS-NH(4)CHEX-OH;cis-4-AMinocyclohexanecar...;CIS-4-AMINOHEXAHYDROBENZOIC ACID;CIS-4-AMINOCYCLOHEXANECARBOXYLIC ACI;AminocyclohexanecarboxylicAcid,cis-4-;4-AMINO CYCLOHEXANE-L-CARBOXYLIC ACID;Ethyl-3(pyridine-2ylamino) propionate;CIS-4-AMINOCYCLOHEXANECARBOXYLIC ACID;cis-4-Aminocyclohexyl carboxylic acid;CIS-4-AMINOCYCLOHEXHANECARBOXYLIC ACID
- CBNumber:
- CB7154506
- Molecular Formula:
- C7H13NO2
- Molecular Weight:
- 143.18
- MDL Number:
- MFCD00191730
- MOL File:
- 3685-23-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| cis-4-Aminocyclohexanecarboxylic Acid >98.0%(GC)(T) | A1448 | 1g | $24 |
| cis-4-Aminocyclohexanecarboxylic Acid >98.0%(GC)(T) | A1448 | 5g | $66 |
| cis-4-Aminocyclohexanecarboxylic Acid >98.0%(GC)(T) | A1448 | 25g | $196 |
| cis-4-Aminocyclohexanecarboxylic Acid | C497405 | 10g | $195 |
| CIS-4-AMINOCYCLOHEXANECARBOXYLIC ACID 95.00% | API0002032 | 1G | $156.82 |
| More product size | |||
| Melting point | 299-301 °C(lit.) |
|---|---|
| Boiling point | 280.0±33.0 °C(Predicted) |
| Density | 9 g/cm3 |
| storage temp. | Inert atmosphere,Room Temperature |
| Water Solubility | Soluble in water |
| solubility | Methanol (Very Slightly), Water (Sparingly) |
| form | Powder |
| pka | 4.62±0.25(Predicted) |
| color | Off-white |
| InChI | InChI=1S/C7H13NO2/c8-6-3-1-5(2-4-6)7(9)10/h5-6H,1-4,8H2,(H,9,10)/t5-,6+ |
| InChIKey | DRNGLYHKYPNTEA-OLQVQODUSA-N |
| SMILES | [C@@H]1(C(O)=O)CC[C@H](N)CC1 |
| CAS DataBase Reference | 3685-23-2(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280a-P304+P340-P405-P501a-P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29224999 | |||||||||
| NFPA 704 |
|
cis-4-Aminocyclohexanecarboxylic acid price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A1448 | cis-4-Aminocyclohexanecarboxylic Acid >98.0%(GC)(T) | 3685-23-2 | 1g | $24 | 2025-07-31 | Buy |
| TCI Chemical | A1448 | cis-4-Aminocyclohexanecarboxylic Acid >98.0%(GC)(T) | 3685-23-2 | 5g | $66 | 2025-07-31 | Buy |
| TCI Chemical | A1448 | cis-4-Aminocyclohexanecarboxylic Acid >98.0%(GC)(T) | 3685-23-2 | 25g | $196 | 2025-07-31 | Buy |
| TRC | C497405 | cis-4-Aminocyclohexanecarboxylic Acid | 3685-23-2 | 10g | $195 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002032 | CIS-4-AMINOCYCLOHEXANECARBOXYLIC ACID 95.00% | 3685-23-2 | 1G | $156.82 | 2021-12-16 | Buy |
cis-4-Aminocyclohexanecarboxylic acid Chemical Properties,Uses,Production
Chemical Properties
off-white powder
Uses
cis-4-Aminocyclohexanecarboxylic Acid is used as a reagent in the synthesis of thiazolylquinazolines
Synthesis
150-13-0
1776-53-0
3685-23-2
The general procedure for the synthesis of 4-aminocyclohexanecarboxylic acid and cis-4-aminocyclohexanecarboxylic acid from p-aminobenzoic acid is as follows: p-aminobenzoic acid (10.0 g, 0.07 mol, 1 eq.), 5% Ru/C catalyst (2.50 g), and 10% NaOH solution (100.0 mL) were added in an autoclave. The mixture was stirred to react under 100 bar hydrogen pressure and 15 bar hydrogen atmosphere. After 20 hours of reaction, the progress of the reaction was detected by thin layer chromatography (TLC), the unfolding agent was dichloromethane/methanol/ammonia (5:5:1, v/v/v), and the staining agent was ninhydrin to confirm that the starting material was completely consumed. Nuclear magnetic resonance (NMR) analysis showed that the reaction was fully converted and the ratio of cis to trans product was 1:4.6. After confirming that the reaction was complete, the reaction was stopped.
References
[1] European Journal of Medicinal Chemistry, 2001, vol. 36, # 3, p. 265 - 286
[2] Biochemische Zeitschrift, 1933, vol. 262, p. 462
[3] Journal of the American Chemical Society, 1938, vol. 60, p. 2341,2343
[4] Chemische Berichte, 1942, vol. 75, p. 425,428
[5] Chemische Berichte, 1943, vol. 76, p. 1019,1023
cis-4-Aminocyclohexanecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29839 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Rionlon ( Tianjin ) Pharmaceutical Co., Ltd. | 0086-13512289226 | yangli@rionlon.com | CHINA | 28 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
View Lastest Price from cis-4-Aminocyclohexanecarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | cis-4-Aminocyclohexanecarboxylic acid
3685-23-2
|
US $0.00 / kg | 1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | |
 |
2024-01-08 | Manufacturers wholesale Cis-4-Amino Cyclohexane Carboxylic Acid CAS NO.3685-23-2 CAS NO.3685-23-2
3685-23-2
|
US $1.00 / G | 100G | 99.9% | 50000 tons | Wuhan Boyuan Import & Export Co., LTD | |
 |
2021-08-18 | cis-4-Aminocyclohexanecarboxylic Acid
3685-23-2
|
US $2.00 / g | 1g | 99% | 30tons | Hebei Binshare New Material Co. Ltd |
-
- cis-4-Aminocyclohexanecarboxylic acid
3685-23-2
- US $0.00 / kg
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Manufacturers wholesale Cis-4-Amino Cyclohexane Carboxylic Acid CAS NO.3685-23-2 CAS NO.3685-23-2
3685-23-2
- US $1.00 / G
- 99.9%
- Wuhan Boyuan Import & Export Co., LTD
-
- cis-4-Aminocyclohexanecarboxylic Acid
3685-23-2
- US $2.00 / g
- 99%
- Hebei Binshare New Material Co. Ltd
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