methyl 3-methyl-1H-indole-6-carboxylate
- CAS No.
- 184151-49-3
- Chemical Name:
- methyl 3-methyl-1H-indole-6-carboxylate
- Synonyms
- Methyl 3-methylindole-6-carboxylate;methyl 3-methyl-1H-indole-6-carboxylate;3-Methyl-1H-indole-6-carboxylic acid Methyl ester;1H-INDOLE-6-CARBOXYLIC ACID, -3-METHYL-, METHYL ESTER
- CBNumber:
- CB71561307
- Molecular Formula:
- C11H11NO2
- Molecular Weight:
- 189.21
- MDL Number:
- MFCD11976828
- MOL File:
- 184151-49-3.mol
- MSDS File:
- SDS
methyl 3-methyl-1H-indole-6-carboxylate price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 309915 | Methyl 3-methyl-1H-indole-6-carboxylate | 184151-49-3 | 250.00mg | $41 | 2026-05-19 | Buy |
| Matrix Scientific | 309915 | Methyl 3-methyl-1H-indole-6-carboxylate | 184151-49-3 | 1.00g | $158 | 2026-05-19 | Buy |
| Matrix Scientific | 309915 | Methyl 3-methyl-1H-indole-6-carboxylate | 184151-49-3 | 5.00g | $626 | 2026-05-19 | Buy |
| aablocks | AA0075Q0 | Methyl 3-Methyl-1H-Indole-6-Carboxylate 98% | 184151-49-3 | 100mg | $13 | 2026-05-28 | Buy |
| aablocks | AA0075Q0 | Methyl 3-Methyl-1H-Indole-6-Carboxylate 98% | 184151-49-3 | 250mg | $29 | 2026-05-28 | Buy |
methyl 3-methyl-1H-indole-6-carboxylate Chemical Properties, Uses, Production
Synthesis
133831-28-4
184151-49-3
Compound 27 (methyl 3-formylindole-6-carboxylate, 0.78 g, 3.84 mmol) was dissolved in anhydrous THF (30 mL) under argon protection and stirred at 0 °C. To this solution was added dropwise a THF solution of borane (1 M, 15.36 mL, 15.36 mmol). The reaction mixture was warmed up to 50 °C and stirred at this temperature for 1 hour. The reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was quenched with saturated aqueous NaHCO3 solution. Subsequently, it was washed with NH4Cl solution (50 mL) and extracted with ethyl acetate (3 x 50 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated in vacuum to give the crude product. The crude product was purified by silica gel column chromatography with eluent 10% EtOAc/hexane to afford compound 28 (methyl 3-methyl-1H-indole-6-carboxylate, 0.36 g, 49.5% yield) as a brown solid.TLC conditions: 30% EtOAc/hexane (Rf: 0.6).1H-NMR (400 MHz, DMSO-d6): δ 11.15 (s, 1H), 8.00 (s, 1H), 7.62-7.55 (m, 2H), 7.37 (s, 1H), 3.84 (s, 3H), 3.27 (s, 3H). lcms observed value (m/z): 189.90 (M + 1).
References
[1] Chemistry - A European Journal, 2016, vol. 22, # 37, p. 13004 - 13009
[2] Patent: WO2018/53157, 2018, A1. Location in patent: Page/Page column 158
[3] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 14, p. 1867 - 1872
[4] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 21, p. 3053 - 3058
[5] Patent: WO2006/100036, 2006, A1. Location in patent: Page/Page column 159-160
methyl 3-methyl-1H-indole-6-carboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 | sales@sun-shinechem.com | China | 1197 | 64 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3989 | 55 |
| Shanghai potentpharm CO.,Ltd | (86) 21 51969655 | China | 486 | 22 | |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Tianjin Anhao Biological Technology Co., Ltd. | sales@ahpharmatech.com | China | 5734 | 55 | |
| NovoChemy Ltd. | 86-(0)21-31261262 373522135 | sales@novochemy.com | China | 6491 | 58 |
| Yancheng KangdiSen Pharmaceutical Co., Ltd. | 13812573443;18052965989 | tongbenwan22@163.com | China | 1975 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| NanJing Xienuo bio Co.,Ltd. | 025-84112752 13805181430 | 154301870@qq.com | China | 999 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Latest Price from methyl 3-methyl-1H-indole-6-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-04 | methyl 3-methyl-1H-indole-6-carboxylate
184151-49-3
|
$1.00 | 1KG | 98% HPLC | 10 tons | Career Henan Chemical Co |
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- methyl 3-methyl-1H-indole-6-carboxylate
184151-49-3
- $1.00
- 98% HPLC
- Career Henan Chemical Co
