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Dimethyl L-cystinate dihydrochloride

CAS No.
32854-09-4
Chemical Name:
Dimethyl L-cystinate dihydrochloride
Synonyms
L-Cys DME 2HCl;(H-Cys-OMe)2·HCl;(L-Cys-OMe)2·2HCl;(H-Cys-OMe)2.2HCI;(H-CYS-OME)2 2 HCL;Cystine Impurity 1;(H-L-Cys-OMe)2·2HCl;DIMETHYL CYSTINATE 2HCL;L-Cystine Dimethyl Ester 2HCl;L-Cystine dimethyl ester DiHCl
CBNumber:
CB7177220
Molecular Formula:
C8H18Cl2N2O4S2
Molecular Weight:
341.28
MDL Number:
MFCD00012490
MOL File:
32854-09-4.mol
MSDS File:
SDS
Last updated:2026-01-13 11:24:37
Product description Number Pack Size Price
L-Cystine dimethyl ester dihydrochloride ≥95% 857327 5g $96.6
L-Cystine dimethyl ester dihydrochloride ≥95% 857327 25g $171
L-Cystine Dimethyl Ester Dihydrochloride >96.0%(T) C3303 5g $31
L-Cystine Dimethyl Ester Dihydrochloride >96.0%(T) C3303 25g $125
L-Cystine dimethyl ester dihydrochloride 269494 5g $383
More product size

Dimethyl L-cystinate dihydrochloride Properties

Melting point 182-183 °C (dec.)(lit.)
alpha -35 º (c=4, MeOH)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO, Methanol, Water
form Powder
color White
optical activity [α]22/D 36.0°, c = 4% in methanol
BRN 4727524
Major Application peptide synthesis
InChI InChI=1/C8H16N2O4S2.2ClH/c1-13-7(11)5(9)3-15-16-4-6(10)8(12)14-2;;/h5-6H,3-4,9-10H2,1-2H3;2*1H/t5-,6-;;/s3
InChIKey QKWGUPFPCRKKMQ-BNTLRKBRSA-N
SMILES [C@H](N)(CSSC[C@H](N)C(=O)OC)C(=O)OC.Cl.Cl |&1:0,6,r|
CAS DataBase Reference 32854-09-4(CAS DataBase Reference)
FDA UNII 9E45OJ92M0
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280a-P304+P340-P405-P501a-P261-P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36-37/39
WGK Germany  3
HS Code  29309090
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

Dimethyl L-cystinate dihydrochloride price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 857327 L-Cystine dimethyl ester dihydrochloride ≥95% 32854-09-4 5g $96.6 2025-07-31 Buy
Sigma-Aldrich 857327 L-Cystine dimethyl ester dihydrochloride ≥95% 32854-09-4 25g $171 2025-07-31 Buy
TCI Chemical C3303 L-Cystine Dimethyl Ester Dihydrochloride >96.0%(T) 32854-09-4 5g $31 2025-07-31 Buy
TCI Chemical C3303 L-Cystine Dimethyl Ester Dihydrochloride >96.0%(T) 32854-09-4 25g $125 2025-07-31 Buy
Usbiological 269494 L-Cystine dimethyl ester dihydrochloride 32854-09-4 5g $383 2021-12-16 Buy
Product number Packaging Price Buy
857327 5g $96.6 Buy
857327 25g $171 Buy
C3303 5g $31 Buy
C3303 25g $125 Buy
269494 5g $383 Buy

Dimethyl L-cystinate dihydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

L-Cystine-dimethyl Ester Dihydrochloride (cas# 32854-09-4) is a compound useful in organic synthesis.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

Measure 150mL of anhydrous methanol in a 250mL round-bottomed flask, slowly add SOCl2 (8.0mL, 108mmol) dropwise, and then add 10g of L-cystine to the reaction solution in batches. After returning to room temperature, refluxed at 60C for 5 h. At the end of the reaction, the solvent was evaporated, and L-cystine dimethyl ester dihydrochloride was obtained by 1:1 crystallization with methanol and petroleum ether, white solid.

67-56-1
56-89-3
32854-09-4
Synthesis of Dimethyl L-cystinate dihydrochloride from Methanol and L-Cystine

Dimethyl L-cystinate dihydrochloride Preparation Products And Raw materials

Global( 229)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
+8617390183901 cynthia@enlaibio.com China 1098 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13799 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29831 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5906 58
Sichuan Jiaying Lai Technology Co.,LTD
18716376478 ycling@enlaibio.com CHINA 302 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58

View Lastest Price from Dimethyl L-cystinate dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(H-L-Cys-OMe)2·2HCl pictures 2026-02-02 (H-L-Cys-OMe)2·2HCl
32854-09-4
US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
Dimethyl L-cystinate dihydrochloride pictures 2025-11-19 Dimethyl L-cystinate dihydrochloride
32854-09-4
US $0.00 / kg 1kg 98.0% 1000kg Shanghai Joiny Pharmaceutical Co.,LTD
L-Cys DME 2HCl pictures 2025-05-07 L-Cys DME 2HCl
32854-09-4
US $580.00 / Kg 0.100Kg 98 5000 Kg R&D Scientific Inc.
DiMethyl L-Cystine dihydrochloride (2R,2'R)-DiMethyl 3,3'-disulfanediylbis(2-aMinopropanoate) dihydrochloride L-Cystine,1,1'-diMethyl ester, hydrochloride (1:2) Methyl 2-amino-3-(((R)-2-amino-3-methoxy-3-oxopropyl)disulfanyl)propanoate dihydrochloride (L-Cys-OMe)2·2HCl (H-L-Cys-OMe)2·2HCl (Disulfide bond) L-Cystine bis(methyl ester) dihydrochloride≥ 98% (TLC) DIMETHYL CYSTINATE 2HCL (H-CYS-OME)2 2 HCL L-CYSTINE DIMETHYL ESTER DIHYDROCHLORIDE dimethyl L-cystinate dihydrochloride L-Cysteinedimethylester hydrochloride L-Cystine Dimethyl Ester 2HCl L-CYSTINE DIMETHYL ESTER DIHYDROCHLORIDE, >=95% L-CYSTINE DIETHYL DIHYDROCHLORIDE methyl (2R)-2-amino-3-{[(2R)-2-amino-3-methoxy-3-oxopropyl]disulfanyl}propanoate dihydrochloride Cystine Impurity 1 (H-Cys-OMe)2 . 2 HCl, (Disulfide bond) Methyl 2-amino-3-(2-amino-3-methoxy-3-oxopropyl)disulfanylpropanoate dihydrochloride L-Cystine dimethyl ester dihydrochloride,98% (H-Cys-OMe)2·HCl Dimethyl 3,3'-disulfanediyl(2R,2'R)-bis(2-aminopropanoate) dihydrochloride [(2R)-3-[[(2R)-2-ammonio-3-methoxy-3-oxopropyl]disulfanyl]-1-methoxy-1-oxopropan-2-yl]ammonium L-cystine dimethyl dihydrochloride L-Cystine dimethyl ester DiHCl Dimethyl L-cystinate dihydrochloride USP/EP/BP [(2R)-3-[[(2R)-2-azaniumyl-3-methoxy-3-oxopropyl]disulfanyl]-1-methoxy-1-oxopropan-2-yl]azanium (H-L-Cys-OMe)2·2HCl L-Cystine, 1,1'-dimethyl ester, hydrochloride Cystine dimethyl ester dihydrochloride (H-Cys-OMe)2.2HCI L-Cystine dimethyl ester dihydrochloride L-Cys DME 2HCl 32854-09-4 CH3OCOCHNH2CH2SSCH2CHNH2COOCH32HCl C8H18Cl2N2O4S2 C8H16N2O4S22HCl C8H18N2O4S2Cl C8H16N2O4S22ClH Amino Acid Derivatives Specialty Synthesis Peptide Synthesis Cysteine/Cystine pharmacetical Chemical Amines Amine Amino Acids & Derivatives Sulfur & Selenium Compounds Amino Acid Derivatives Cysteine/Cystine Peptide Synthesis