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6-Chloroimidazo[2,1-f]pyridazine

CAS No.
6775-78-6
Chemical Name:
6-Chloroimidazo[2,1-f]pyridazine
Synonyms
6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE;6-chloroimidazo[1,2-b]pyr...;6-Chloroimidazo[2,1-b]pyridazine;6-сhloroimidazo[1,2-b]pyridazine;6-Chloroimidazo[2,1-f]pyridazine;6-Chloroimidazo[l, 2-b]pyridazine;IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-;6-Chloroimidazo[1,2-b]pyridazine 98%;6-Chloroimidazo[2,1-f]pyridazine ISO 9001:2015 REACH;High purity CAS 6775-78-6 6-Chloroimidazo[2,1-f]pyridazine in stock
CBNumber:
CB7187061
Molecular Formula:
C6H4ClN3
Molecular Weight:
153.57
MDL Number:
MFCD07778345
MOL File:
6775-78-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:41:39
Product description Number Pack Size Price
6-Chloroimidazo[1,2-b]pyridazine >98.0%(GC)(T) C3127 1g $23
6-Chloroimidazo[1,2-b]pyridazine >98.0%(GC)(T) C3127 5g $69
6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE 97% 37130 5G $33
6-Chloro-imidazo[1,2-b]pyridazine FC11286 50g $238
6-Chloro-imidazo[1,2-b]pyridazine FC11286 100g $381
More product size

6-Chloroimidazo[2,1-f]pyridazine Properties

Melting point 114.0 to 118.0 °C
Density 1.51±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 3.68±0.30(Predicted)
form powder to crystal
color White to Gray to Brown
InChI InChI=1S/C6H4ClN3/c7-5-1-2-6-8-3-4-10(6)9-5/h1-4H
InChIKey MPZDNIJHHXRTIQ-UHFFFAOYSA-N
SMILES C12=NC=CN1N=C(Cl)C=C2
CAS DataBase Reference 6775-78-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  36/37/39
HazardClass  IRRITANT
HS Code  2933599590

6-Chloroimidazo[2,1-f]pyridazine price More Price(94)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C3127 6-Chloroimidazo[1,2-b]pyridazine >98.0%(GC)(T) 6775-78-6 1g $23 2026-04-30 Buy
TCI Chemical C3127 6-Chloroimidazo[1,2-b]pyridazine >98.0%(GC)(T) 6775-78-6 5g $69 2026-04-30 Buy
AstaTech 37130 6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE 97% 6775-78-6 5G $33 2026-04-30 Buy
Biosynth FC11286 6-Chloro-imidazo[1,2-b]pyridazine 6775-78-6 50g $238 2026-06-04 Buy
Biosynth FC11286 6-Chloro-imidazo[1,2-b]pyridazine 6775-78-6 100g $381 2026-06-04 Buy
Product number Packaging Price Buy
C3127 1g $23 Buy
C3127 5g $69 Buy
37130 5G $33 Buy
FC11286 50g $238 Buy
FC11286 100g $381 Buy

6-Chloroimidazo[2,1-f]pyridazine Chemical Properties,Uses,Production

Physical State

White to Gray to Brown powder to crystal

Uses

6-chloroimidazo[1,2-b]pyridazine (cas# 6775-78-6) is a useful research chemical.

Safe handling

Handling is performed in a well ventilated place.Wear suitable protective equipment.Prevent dispersion of dust.Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Avoid contact with skin,eyes and clothing.

Synthesis

6-Chloropyridazin-3-amine

5469-69-2

Bromoacetaldehyde diethyl acetal

2032-35-1

6-Chloroimidazo[2,1-f]pyridazine

6775-78-6

General procedure for the preparation of 6-chloroimidazo[1,2-b]pyridazine: Bromoacetaldehyde diethyl acetal (13.7 g, 69.5 mmol, 1.8 eq.) was added to hydrobromic acid (4.0 mL) and heated to reflux for 1.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently poured into an isopropanol reaction flask containing an excess of sodium bicarbonate. After stirring for 3 minutes, filtration was performed. To the filtrate was added 3-amino-6-chloropyridazine (5.0 g, 38.6 mmol, 1.0 eq.) and the reflux was continued by heating for 2 hours. At the end of the reaction, the reaction mixture was quenched with water and extracted with ethyl acetate. Finally, the product was purified by column chromatography to give 5.1 g of brown solid in 86% yield. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.89 (s, 1H), 7.88 (d, J = 9.3 Hz, 1H), 7.74 (s, 1H), 7.01 (d, J = 9.3 Hz, 1H).

References

[1] Patent: US2014/256733, 2014, A1. Location in patent: Paragraph 0227-0229
[2] Patent: WO2012/69202, 2012, A1. Location in patent: Page/Page column 46
[3] Patent: EP2463289, 2012, A1. Location in patent: Page/Page column 17-18
[4] Patent: EP2818471, 2014, A1. Location in patent: Paragraph 0117; 0118
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 6, p. 2789 - 2798

107-20-0
5469-69-2
6775-78-6
Synthesis of 6-Chloroimidazo[2,1-f]pyridazine from Chloroacetaldehyde and 6-Chloropyridazin-3-amine
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View Lastest Price from 6-Chloroimidazo[2,1-f]pyridazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Chloroimidazo[1,2-b]pyridazine pictures 2026-06-05 6-Chloroimidazo[1,2-b]pyridazine
6775-78-6
$6.00-80.00 5g 0.98 25kg Shanghai UCHEM Inc.
6-Chloroimidazo[2,1-f]pyridazine  pictures 2025-11-18 6-Chloroimidazo[2,1-f]pyridazine
6775-78-6
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
6-Chloroimidazo[1,2-b]pyridazine pictures 2025-09-25 6-Chloroimidazo[1,2-b]pyridazine
6775-78-6
$1.00-200.00 1KG 99% Henan Fengda Chemical Co., Ltd

6-Chloroimidazo[2,1-f]pyridazine Spectrum

6-сhloroimidazo[1,2-b]pyridazine 6-Chloroimidazo[1,2-b]pyridazine 98% IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO- 6-Chloroimidazo[2,1-f]pyridazine 6-chloroimidazo[1,2-b]pyr... 6-Chloroimidazo[2,1-f]pyridazine ISO 9001:2015 REACH High purity CAS 6775-78-6 6-Chloroimidazo[2,1-f]pyridazine in stock 6-Chloroimidazo[2,1-b]pyridazine 6-Chloroimidazo[l, 2-b]pyridazine 6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE 6775-78-6 6755-78-6 C6H5ClN3 Chemical Synthesis Heterocyclic Building Blocks New Products for Chemical Synthesis Pyridazines Halides Building Blocks Pyridazine Fused Ring Systems Imidazo[x,x-y]pyridazine blocks Heterocycles Pyridines