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D-ASPARTIC ACID-BETA-METHYL ESTER

CAS No.
21394-81-0
Chemical Name:
D-ASPARTIC ACID-BETA-METHYL ESTER
Synonyms
D-Asp(Ome).HCl;D-Asp(OMe)-OH·HCl;H-D-Aspartic acid-;D-ASPARTICACID-β-METHYLESTER;β-Methyl (2R)-aspartate ester;D-Aspartic acid-β-methyl ester;H-D-Aspartic acid-β-methyl ester;D-ASPARTIC ACID-BETA-METHYL ESTER;H-D-ASPARTIC ACID-SS-METHYL ESTER;H-D-ASPARTIC ACID-BETA-METHYL ESTER
CBNumber:
CB7191668
Molecular Formula:
C5H9NO4
Molecular Weight:
147.13
MDL Number:
MFCD06797583
MOL File:
21394-81-0.mol
MSDS File:
SDS
Last updated:2025-08-08 17:45:00
Product description Number Pack Size Price
D-Asparticacidβ-methylesterhydrochloride,99%(Assay) 99%(Assay) 05942 1G $72.8
D-Aspartic acid beta-methyl ester hydrochloride FA48674 500mg $95
D-ASPARTIC ACID-BETA-METHYL ESTER 95.00% AAA0003800 5G $179.55
D-Asparticacid-beta-methylester V1600 25g $235
D-Aspartic acid beta-methyl ester hydrochloride FA48674 2g $260
More product size

D-ASPARTIC ACID-BETA-METHYL ESTER Properties

Melting point 188-190 °C
Boiling point 301.7±37.0 °C(Predicted)
Density 1.299
storage temp. Sealed in dry,Room Temperature
pka 2.16±0.23(Predicted)
Appearance White to off-white Solid
optical activity 23.2°(C=1.00g/100ml MEOH)

D-ASPARTIC ACID-BETA-METHYL ESTER price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Chem-Impex 05942 D-Asparticacidβ-methylesterhydrochloride,99%(Assay) 99%(Assay) 21394-81-0 1G $72.8 2021-12-16 Buy
Biosynth Carbosynth FA48674 D-Aspartic acid beta-methyl ester hydrochloride 21394-81-0 500mg $95 2021-12-16 Buy
American Custom Chemicals Corporation AAA0003800 D-ASPARTIC ACID-BETA-METHYL ESTER 95.00% 21394-81-0 5G $179.55 2021-12-16 Buy
AK Scientific V1600 D-Asparticacid-beta-methylester 21394-81-0 25g $235 2021-12-16 Buy
Biosynth Carbosynth FA48674 D-Aspartic acid beta-methyl ester hydrochloride 21394-81-0 2g $260 2021-12-16 Buy
Product number Packaging Price Buy
05942 1G $72.8 Buy
FA48674 500mg $95 Buy
AAA0003800 5G $179.55 Buy
V1600 25g $235 Buy
FA48674 2g $260 Buy

D-ASPARTIC ACID-BETA-METHYL ESTER Chemical Properties,Uses,Production

Definition

ChEBI: Methyl gamma-D-aspartate is a dicarboxylic acid monoester obtained by condensation of the side-chain carboxy group of D-aspartic acid with methanol. It has a role as a bacterial metabolite. It is a D-aspartic acid derivative and a dicarboxylic acid monoester.

Synthesis

Methanol

67-56-1

D-Aspartic acid

1783-96-6

D-ASPARTIC ACID-BETA-METHYL ESTER

21394-81-0

At 0 °C, 73.7 mL of acetyl chloride (1.4 eq.) was slowly added dropwise to 250 mL of methanol. Maintaining 0 °C, the mixture was added dropwise to a 250 mL methanol suspension containing 100 g (751 mmol) of (R)-2-aminosuccinic acid. The reaction mixture was stirred at 0 °C for 3 h before gradually warming to room temperature and continuing to stir overnight. Five identical reaction vials were set up in parallel for the same operation. The mixtures from all six reaction flasks were combined and concentrated under reduced pressure. The concentrated residue was treated with methyl tert-butyl ether (MTBE) and the resulting precipitate was filtered and dried under reduced pressure to give (R)-2-amino-4-methoxy-4-oxobutanoic acid (600 g, 90% yield) as a white solid. The product was characterized by 1H NMR (400 MHz, deuterium oxide): δ 4.33 (t, J = 5.5 Hz, 1H), 3.81 (s, 1H), 3.72 (s, 3H), 3.10 (d, J = 4.9 Hz, 2H).

References

[1] Patent: WO2017/89458, 2017, A1. Location in patent: Page/Page column 72
[2] Gazzetta Chimica Italiana, 1986, vol. 116, # 10, p. 607 - 608
[3] Patent: CN106518701, 2017, A. Location in patent: Paragraph 0021-0022

D-ASPARTIC ACID-BETA-METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 92)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
+8617390183901 cynthia@enlaibio.com China 1100 58
Capot Chemical Co.,Ltd.
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+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
GL Biochem(Binhai) Ltd.
+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58

View Lastest Price from D-ASPARTIC ACID-BETA-METHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
D-Asp(Ome).HCl pictures 2025-10-16 D-Asp(Ome).HCl
21394-81-0
US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
  • D-Asp(Ome).HCl pictures
  • D-Asp(Ome).HCl
    21394-81-0
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd

D-ASPARTIC ACID-BETA-METHYL ESTER Spectrum

D-ASPARTIC ACID-BETA-METHYL ESTER H-D-Aspartic acid-β-methyl ester D-Aspartic acid-β-methyl ester β-Methyl (2R)-aspartate ester H-D-ASPARTIC ACID-SS-METHYL ESTER D-Asp(OMe)-OH·HCl D-Aspartic acid ?-methyl ester hydrochloride99% D-Asp(Ome).HCl (R)-2-AMino-4-Methoxy-4-oxobutanoic acid H-D-Aspartic acid- H-D-Aspartic acid-β-methyl ester, BR (2R)-2-amino-4-methoxy-4-oxobutanoic acid D-ASPARTICACID-β-METHYLESTER D-ASPARTIC ACID-BETA-METHYL ESTER USP/EP/BP H-D-ASPARTIC ACID-BETA-METHYL ESTER D-Aspartic acid β-methyl ester hydrochloride (2R)-2-azaniumyl-4-methoxy-4-oxobutanoate D-Aspartic acid, 4-methyl ester (9CI, ACI) 21394-81-0