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(S)-1-(4-FLUOROPHENYL)ETHYLAMINE

(S)-1-(4-FLUOROPHENYL)ETHYLAMINE structure

CAS No.: 66399-30-2

Chemical Name:: (S)-1-(4-FLUOROPHENYL)ETHYLAMINE

Synonyms: (S)-1-(4-FLUOROPHENYL)ETHANAMINE;(S)-1-(4-fluorophenyl)ethan-1-amine;S-PF-PEM;(S)-(-)-4-F-phenylethylamine;1(S)-(4-Fluorophenyl)ethylamine;(S)-1-(4-FLUOROPHENYL)ETHYLAMINE;(s)-4-fluoro-à-methylbenzylamine;(S)-α-Methyl-4-fluorobenzylaMine;(S)-4-Fluoro-α-methylbenzylamine;(1S)-1-(4-Fluorophenyl)ethylamine

CBNumber:: CB7200810

Molecular Formula:: C8H10FN

Molecular Weight:: 139.17

MDL Number:: MFCD03092999

MOL File:: 66399-30-2.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:51

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(S)-1-(4-FLUOROPHENYL)ETHYLAMINE Properties

Melting point	-30°C
Boiling point	76°C 22mm
Density	1,03 g/cm³
refractive index	1.501
Flash point	76°C/22mm
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	Miscible with dimethyl sulfoxide.
pka	8.98±0.10(Predicted)
form	liquid
color	Clear
optical activity	Consistent with structure
Sensitive	Air Sensitive
BRN	6791614
CAS DataBase Reference	66399-30-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07,GHS09

Signal word

Danger

Hazard statements

H302-H314-H411-H227

Precautionary statements

P273-P280-P305+P351+P338-P310-P210e-P260h-P303+P361+P353-P405-P501a

Hazard Codes

Xi,N,C

Risk Statements

34-51/53-22

Safety Statements

26-36/37/39-61-45

RIDADR

2735

Hazard Note

Irritant

HazardClass

PackingGroup

III

HS Code

2921490090

NFPA 704

	2
3		0

(S)-1-(4-FLUOROPHENYL)ETHYLAMINE price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	F1392	(S)-1-(4-Fluorophenyl)ethan-1-amine min. 98.0 %	66399-30-2	1G	$72	2025-07-31	Buy
TCI Chemical	F1392	(S)-1-(4-Fluorophenyl)ethan-1-amine min. 98.0 %	66399-30-2	5G	$216	2025-07-31	Buy
SynQuest Laboratories	3630-3-S4	(S)-1-(4-Fluorophenyl)ethylamine 97%	66399-30-2	25g	$345	2021-12-16	Buy
Apolloscientific	PC0613	(1S)-1-(4-Fluorophenyl)ethylamine	66399-30-2	5g	$174	2021-12-16	Buy
SynQuest Laboratories	3630-3-S4	(S)-1-(4-Fluorophenyl)ethylamine 97%	66399-30-2	5G	$115	2021-12-16	Buy

Product number	Packaging	Price	Buy
F1392	1G	$72	Buy
F1392	5G	$216	Buy
3630-3-S4	25g	$345	Buy
PC0613	5g	$174	Buy
3630-3-S4	5G	$115	Buy

(S)-1-(4-FLUOROPHENYL)ETHYLAMINE Chemical Properties,Uses,Production

Chemical Properties

Colorless transparent liquid

Uses

(S)-(-)-1-(4-Fluorophenyl)ethylamine is used in organic synthesis. It acts as a ligand and form a coordination complex, diacetato-2-O-bis[(S)-1-(4-fluorophenyl)ethylamine-N]palladium(II) by reacting with palladium(II) acetate.

Synthesis

403-42-9

66399-30-2

General procedure for the synthesis of (S)-1-(4-fluorophenyl)ethylamine using 4-fluoroacetophenone as starting material: to a vial containing 4-fluoroacetophenone (0.2 mmol, 1.0 eq.), ammonium formate (HCO2NH4, 37.8 mg, 2 mmol, 10.0 eq.), and Pdα-nanocatalyst (Pd°-AmP-MFC, 2.68 mg. 0.002 mmol, 8 wt%) were added to the vial with methanol (0.3 mL) and the reaction mixture was stirred for the time indicated in Table 4. Upon completion of the reaction, the vials were cooled in an ice bath, followed by the addition of methanol (0.367 mL) and a buffer solution (50 mM HEPES, pH 8.2, 6 mL) containing aminotransferase (ATA) and 2-5 equivalents of sodium pyruvate (1 equivalent = 0.2 mmol, 22 mg). The reaction tubes were placed under light-avoiding conditions and left to stand at room temperature for 24 h with gentle shaking on an orbital oscillator. Upon completion of the reaction, the enantiomeric excess (ee) of the product was determined by high performance liquid chromatography (HPLC) analysis (repeated three times for each sample).

References

[1] Patent: WO2016/96905, 2016, A1. Location in patent: Page/Page column 25
[2] Chemistry Letters, 2004, vol. 33, # 11, p. 1424 - 1425
[3] Journal of Organic Chemistry, 2013, vol. 78, # 11, p. 5314 - 5327
[4] Organic Process Research and Development, 2014, vol. 18, # 6, p. 788 - 792
[5] ACS Catalysis, 2016, vol. 6, # 6, p. 3932 - 3940

(S)-1-(4-FLUOROPHENYL)ETHYLAMINE Preparation Products And Raw materials

Raw materials

1-(4-FLUOROPHENYL)ETHYLAMINE (S)-1-Phenyl-N-((S)-1-(4-(fluoro)phenyl)ethyl)etha n-1-amine 4-Fluoroacetophenone isopropyl 2-Methoxyacetate Benzenemethanamine, 4-fluoro-α-methyl-N-[(1S)-1-phenylethyl]-, (αR)-

Sodium pyruvate Ammonium formate Methanol

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Preparation Products

(S)-1-(4-FLUOROPHENYL)ETHYLAMINE Suppliers

Global( 118)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Chengdu Feibo Pharm Technology Co., Ltd	+86 028-84641798 15982321820	abby@arkpharm.com	China	10922	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
LEAP CHEM CO., LTD.	+86-852-30606658 19957148339;	market18@leapchem.com	China	24727	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Chengdu Feibo Pharm Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hangzhou Huarong Pharm Co., Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
LEAP CHEM CO., LTD.	58

View Lastest Price from (S)-1-(4-FLUOROPHENYL)ETHYLAMINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-07-25	(S)-1-(4-FLUOROPHENYL)ETHYLAMINE 66399-30-2	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
	2019-07-06	(S)-1-(4-FLUOROPHENYL)ETHYLAMINE 66399-30-2	US $7.00 / KG	1KG	99%	1000KG	Career Henan Chemical Co

(S)-1-(4-FLUOROPHENYL)ETHYLAMINE
66399-30-2
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

(S)-1-(4-FLUOROPHENYL)ETHYLAMINE
66399-30-2
US $7.00 / KG
99%
Career Henan Chemical Co

66399-30-2((S)-1-(4-FLUOROPHENYL)ETHYLAMINE)Related Search:

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(S)-1-(4-FLUOROPHENYL)ETHANAMINE (S)-(-)-1-(4-FLUOROPHENYL)ETHYLAMINE (S)-1-(4-FLUOROPHENYL)ETHYLAMINE S-PF-PEM (S)-4-Fluoro-alpha-methylbenzylamine (s)-4-fluoro-à-methylbenzylamine (S)-(-)-1-(4-Fluorophenyl)ethylamine, ChiPros 99%, ee 99% Benzenemethanamine, 4-fluoro-α-methyl-, (αS)- Benzenemethanamine, 4-fluoro-.alpha.-methyl-, (.alpha.S)- (1S)-1-(4-Fluorophenyl)ethylamine (S)-1-(4-FLUOROPHENYL)ETHYLAMINE-HCl (S)-1-(4-Fluorophenyl)ethylaMine hydrochloride (S)-α-Methyl-4-fluorobenzylaMine (1S)-1-(4-fluorophenyl)ethan-1-aMine (S)-4-Fluoro-α-methylbenzylamine (S)-1-(4-Fluorophenyl)ethylamine hydrochloride, >=95% (S)-(-)-1-(4-Fluorophenyl)ethylamine, 99%, ee 99+% (S)-1-(4-fluorophenyl)ethan-1-amine (1S)-1-(4-fluorophenyl)ethanamine (S)-(-)-4-F-phenylethylamine 1(S)-(4-Fluorophenyl)ethylamine 66399-30-2