ChemicalBook >> CAS DataBase List >>(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

CAS No.
179686-45-4
Chemical Name:
(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM
Synonyms
3-N-Boc-AMino-epsilon-caprolactaM;N-2-BOC-AMINOCAPROLACTAM;3-N-BOC-AMINO-2-AZEPANONE;3-(Boc-amino)-2-azepanone;tert-butyl 2-oxoazepan-3-ylcarbaMate;(+/-)-N--Boc-Amino-epsilon-caprolactam;ert-butylN-(2-oxoazepan-3-yl)carbamate;(+/-)-N-A-BOC-AMINO-EPSILON-CAPROLACTAM;R-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM;(+/-)-N-a-Boc-Amino-epsilon-caprolactam
CBNumber:
CB7203725
Molecular Formula:
C11H20N2O3
Molecular Weight:
228.29
MDL Number:
MFCD02183574
MOL File:
179686-45-4.mol
MSDS File:
SDS
Last updated:2026-05-28 03:06:46
Product description Number Pack Size Price
(+/-)-N-a-Boc-Amino-epsilon-caprolactam EHA68645 5g $472
3-N-Boc-Amino-epsilon-caprolactam 119288 1.00g $270
3-N-Boc-Amino-epsilon-caprolactam 119288 5.00g $810
3-N-Boc-Amino-epsilon-caprolactam 119288 10.00g $1296
tert-butyl N-(2-oxoazepan-3-yl)carbamate 95% B83796 500mg $43

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Properties

Boiling point 417.7±34.0 °C(Predicted)
Density 1.09
storage temp. 2-8°C(protect from light)
pka 11.05±0.20(Predicted)
Appearance White to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth EHA68645 (+/-)-N-a-Boc-Amino-epsilon-caprolactam 179686-45-4 5g $472 2026-06-04 Buy
Matrix Scientific 119288 3-N-Boc-Amino-epsilon-caprolactam 179686-45-4 1.00g $270 2026-05-18 Buy
Matrix Scientific 119288 3-N-Boc-Amino-epsilon-caprolactam 179686-45-4 5.00g $810 2026-05-18 Buy
Matrix Scientific 119288 3-N-Boc-Amino-epsilon-caprolactam 179686-45-4 10.00g $1296 2026-05-18 Buy
Synthonix B83796 tert-butyl N-(2-oxoazepan-3-yl)carbamate 95% 179686-45-4 500mg $43 2026-05-06 Buy
Product number Packaging Price Buy
EHA68645 5g $472 Buy
119288 1.00g $270 Buy
119288 5.00g $810 Buy
119288 10.00g $1296 Buy
B83796 500mg $43 Buy

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Chemical Properties,Uses,Production

Synthesis

Di-tert-butyl dicarbonate

24424-99-5

D-alpha-Amino-epsilon-caprolactam

28957-33-7

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

179686-45-4

Example 2 Preparation of 3-(S)-tert-butoxycarbonylamino-4,5,6,7-tetrahydroacridoheptan-2-one (4): di-tert-butyl dicarbonate (25.5 g, 0.11 mol) was slowly added to a stirring solution of L-α-amino-ε-caprolactam (compound 3) (15 g, 0.11 mol) and potassium carbonate (26.7 g, 0.11 mol) in a solution of tetrahydrofuran (THF). Once the addition was complete, the reaction mixture was gradually warmed to room temperature and the reaction was continued with stirring for 18 hours. After completion of the reaction, the insoluble solids were removed by filtration and the filtrate was concentrated under reduced pressure to remove the solvent to afford 26.4 g (99% yield) of 3-N-Boc-aminoazepan-2-one (4) as a white solid. Thin layer chromatography (TLC) showed an Rf value of 0.91 (unfolding agent: hexane-ethyl acetate, 9:1). Mass spectrometry (electrospray) showed a molecular ion peak m/z 229 ([M+H]+). Nuclear magnetic resonance hydrogen spectrum (1H-NMR, CDCl3) δ: 1.39 (m, 2H), 1.50 (s, 9H), 1.82 (m, 2H), 2.03 (m, 2H), 3.25 (m, 2H), 4.29 (m, 1H), 5.91 (s, 1H), 6.36 (s, 1H).

References

[1] Patent: US6534495, 2003, B1
[2] Patent: US6541467, 2003, B1
[3] Patent: US6218365, 2001, B1

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Preparation Products And Raw materials

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Suppliers

Global( 70)Suppliers
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Alchem Pharmtech,Inc.
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JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9976 60
N-(Hexahydro-2-oxo-1H-azepin-3-yl)carbamic acid tert-butyl ester (+/-)-N-Alpha-Boc-AMino-Epsilon-CaprolaCLaM (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM N-2-BOC-AMINOCAPROLACTAM (RS)-N-BOC-ALPHA-AMINO-EPSILON-CAPROLACTAME (+/-)-N--Boc-Amino-epsilon-caprolactam (+/-)-N-A-BOC-AMINO-EPSILON-CAPROLACTAM Carbamic acid, N-(hexahydro-2-oxo-1H-azepin-3-yl)-, 1,1-dimethylethyl ester tert-butyl 2-oxoazepan-3-ylcarbaMate tert-butyl N-(2-oxoazepan-3-yl)carbamate R-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Carbamic acid, (hexahydro-2-oxo-1H-azepin-3-yl)-, 1,1-dimethylethyl ester 3-N-BOC-AMINO-2-AZEPANONE (+/-)-(2-OXO-AZEPAN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER 3-(Boc-amino)-2-azepanone ert-butylN-(2-oxoazepan-3-yl)carbamate Hydrazinecarbothioamide,N-(6-methoxyphenyl)- 3-tert-butyloxyamide nitrogen-containing heterocyclic heptane 2-Methyl-2-propanyl (2-oxo-3-azepanyl)carbamate (+/-)-N-a-Boc-Amino-epsilon-caprolactam tert-butyl N-(2-oxoazepan-3-yl)carbamate - [B83796] (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM 3-N-Boc-AMino-epsilon-caprolactaM 179686-45-4