5-Hydroxy isatin
- CAS No.
- 116569-09-6
- Chemical Name:
- 5-Hydroxy isatin
- Synonyms
- 5-Hydroxy isatin;Flumazenil Impurity 17;5-hydroxyindoline-2,3-dione;5-Hydroxy-1H-indole-2,3-dione;1H-Indole-2,3-dione, 5-hydroxy-;5-hydroxy-2,3-dihydro-1H-indole-2,3-dione;5-Hydroxy isatin 5-Hydroxy indole-2,3-dione
- CBNumber:
- CB72455151
- Molecular Formula:
- C8H5NO3
- Molecular Weight:
- 163.13
- MDL Number:
- MFCD11007925
- MOL File:
- 116569-09-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P305+P351+P338-P332+P313-P362+P364-P337+P313 | |||||||||
| NFPA 704 |
|
5-Hydroxy isatin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 36383 | 5-hydroxy Isatin ≥98% | 116569-09-6 | 10mg | $136 | 2026-04-30 | Buy |
| Cayman Chemical | 36383 | 5-hydroxy Isatin ≥98% | 116569-09-6 | 50mg | $608 | 2026-04-30 | Buy |
| Cayman Chemical | 36383 | 5-hydroxy Isatin ≥98% | 116569-09-6 | 100mg | $1078 | 2026-04-30 | Buy |
| Biosynth | REA56909 | 5-Hydroxy-2,3-dihydro-1H-indole-2,3-dione | 116569-09-6 | 50mg | $307 | 2026-06-05 | Buy |
| Biosynth | REA56909 | 5-Hydroxy-2,3-dihydro-1H-indole-2,3-dione | 116569-09-6 | 0.5g | $1056.1 | 2026-06-05 | Buy |
5-Hydroxy isatin Chemical Properties, Uses, Production
Uses
5-Hydroxyisatin can be used to synthesize anti-cancer agents[1].
Biological Activity
5-hydroxy Isatin is an inhibitor of monoamine oxidase A (MAO-A; IC50 = 8.4 μM).1 It is selective for MAO-A over MAO-B (IC50 = >100 μM). 5-hydroxy Isatin (50 μM) also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.2
References
1.Medvedev, A.E., Goodwin, B., Chow, A., et al.Inhibitory potency of some isatin analogues on human monoamine oxidase A and BBiochem. Pharmacol.44(3)590-592(1992) 2.Medvedev, A.E., Goodwin, B.L., Sandler, M., et al.Efficacy of isatin analogues as antagonists of rat brain and heart atrial natriuretic peptide receptors coupled to particulate guanylyl cyclaseBiochem. Pharmacol.57(8)913-915(1999)
5-Hydroxy isatin Preparation Products And Raw materials
Raw materials
Preparation Products
5-Hydroxy isatin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9883 | 50 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Zhen Li Biological Technology Co., Ltd | 021-16621358918; 18516310516;16621358918;13045646768 | zhenlipharma888@163.com | China | 19060 | 58 |
| Zhaoqing Wanwei New Material Technology Co., Ltd. | 0755-1328880-4488 13049823633;13068786899;13288804488 | 13288804488@163.com | China | 623 | 58 |
| Shenzhen Botel Biotechnology Co. Ltd. | 13316949107 13316968096 | 1979313431@qq.com | China | 9619 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52651 | 58 |
