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ChemicalBook >> CAS DataBase List >>(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol Structure
(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol structure
CAS No.
155899-66-4
Chemical Name:
(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
Synonyms
(3aR,4S,6R,6aS)-6-aMino-2,2-diMethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol;Ticagrelor-24;TICAGRELOR int;Ticagrelor Impurity 102;Ticagrelor Related Compound 1;2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol;(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-…;Ticagrelor Related Compound 1（rac-tartaric acid dibenzoate）;6-AMinotetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-ol;(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta...
CBNumber:
CB72510113
Molecular Formula:
C8H15NO3
Molecular Weight:
173.21
MDL Number:
MFCD20527303
MOL File:
155899-66-4.mol
MSDS File:
SDS
Last updated:2026-05-28 03:29:59
Request For Quotation

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol Properties

Melting point 85-88℃
Boiling point 288℃
Density 1.170
Flash point 128℃
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 14.03±0.60(Predicted)
form Solid
color White to Pale Beige
optical activity 9.1°(C=0.30g/100ml CHCL3)
Stability Hygroscopic
InChI InChI=1S/C8H15NO3/c1-8(2)11-6-4(9)3-5(10)7(6)12-8/h4-7,10H,3,9H2,1-2H3/t4-,5+,6+,7-/m1/s1
InChIKey AXPYGRDXRLICKY-JRTVQGFMSA-N
SMILES O1[C@@]2([H])[C@H](N)C[C@H](O)[C@@]2([H])OC1(C)C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P301+P312-P305+P351+P338
HS Code  2932990090

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 427863 (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol 155899-66-4 10mg $496 2026-06-03 Buy
Usbiological 427863 (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol 155899-66-4 25mg $914 2026-06-03 Buy
Apolloscientific OR920122 (3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3ah-cyclopenta[d][1,3]dioxol-4-ol 98% 155899-66-4 1g $21 2026-06-04 Buy
Apolloscientific OR920122 (3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3ah-cyclopenta[d][1,3]dioxol-4-ol 98% 155899-66-4 5g $26 2026-06-04 Buy
Apolloscientific OR920122 (3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3ah-cyclopenta[d][1,3]dioxol-4-ol 98% 155899-66-4 25g $64 2026-06-04 Buy
Product number Packaging Price Buy
427863 10mg $496 Buy
427863 25mg $914 Buy
OR920122 1g $21 Buy
OR920122 5g $26 Buy
OR920122 25g $64 Buy

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol Chemical Properties, Uses, Production

Uses

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol was used to preapare AZD6140 as an orally active reversible P2Y12 receptor antagonist for prevention of thrombosis.

Synthesis

0.86 g of p-toluenesulfonic acid was added to a solution of 15.0 g of the precursor compound in acetone ( 250 ml ) followed by 22 ml of 2,2 -dimethoxypropane, and the resulting reaction mixture was stirred at room temperature for 30 minutes. At the end of the reaction the mixture was separated by extraction between ethyl acetate ( 700 ml ) and brine ( 300 ml ), the organic layer was separated and concentrated, water was added to the residue, which was heated and refluxed for 24 h. At the end of the reaction the reaction solution was concentrated under reduced pressure and azeotropized with toluene to remove water to give (3AR,4S,6R,6AS)-6-aminotetrahydro-2,2-dimethyl-4H- cyclopenteno-1,3-dioxolan-4-ol.

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol synthesis

60410-16-4
155899-66-4
Synthesis of (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol from (1R,3S)-4-Cyclopentene-1,3-diol 1-acetate

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol Preparation Products And Raw materials

Raw materials

4H-Cyclopenta-1,3-dioxol-4-ol, tetrahydro-2,2-dimethyl-6-[(phenylmethyl)amino]-, (3aR,4S,6R,6aS)- D-erythro-Pent-4-enitol, 1,4,5-trideoxy-2,3-O-(1-methylethylidene)-1-[oxido(phenylmethyl)imino]-, (1Z)- D-erythro-Pent-4-enose, 4,5-dideoxy-2,3-O-(1-methylethylidene)- (9CI) 4,7-Methano-4H-1,3-dioxolo[4,5-d][1,2]oxazine, tetrahydro-2,2-dimethyl-6-(phenylmethyl)-, (3aS,4S,7R,7aS)- (1R,3S)-4-Cyclopentene-1,3-diol 1-acetate
(3aS,4S,6R,6aR)-4-(iodoMethyl)-6-Methoxy-2,2-diMethyltetrahydrofuro[3,4-d][1,3]dioxole 2,2-Dimethoxypropane

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Preparation Products

Ethyl 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate oxalate

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol Suppliers

Global Suppliers ( 218)
Supplier Tel Email Country ProdList Advantage
Suzhou Xinkai Bio-Medical Technology Co., Ltd. 0512-67213637 13952409868 peter19zhang@163.com China 442 55
Suzhou lipin Chemical Co., Ltd 0512-0512-67509664 19888480046 China 121 58
Suzhou lipin Chemical Co., Ltd 0512-67509664 19888480046 3516936381@qq.com China 111 58
Suzhou Yuanhuan Pharmaceutical Technology Co., Ltd. 0512-18136053398 18136053398 2982784935@qq.com China 80 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Jiangsu Vcare PharmaTech Co., Ltd. 025-58741518 13327700685 sales@vcarepharmatech.com China 281 61
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Supplier Advantage
Suzhou Xinkai Bio-Medical Technology Co., Ltd. 55
Suzhou lipin Chemical Co., Ltd 58
Suzhou lipin Chemical Co., Ltd 58
Suzhou Yuanhuan Pharmaceutical Technology Co., Ltd. 58
Shanghai Boyle Chemical Co., Ltd. 55
Beijing Ouhe Technology Co., Ltd 60
Adamas Reagent, Ltd. 59
Shanghai Hanhong Scientific Co.,Ltd. 64
Jiangsu Vcare PharmaTech Co., Ltd. 61
China DongFan Chemical Co.,LTD 66

View Latest Price from (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol pictures 2023-07-19 (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
155899-66-4
 $30.00 1KG 99% 20 Tons Wuhan wingroup Pharmaceutical Co., Ltd
(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol pictures 2023-03-10 (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
155899-66-4
 $99.00 99.0%min 3000kgs/month Weijer International Trade (Hebei) Co., Ltd.
(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol pictures 2021-07-13 (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
155899-66-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol Spectrum

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol(155899-66-4)1HNMR

155899-66-4 ((3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol) Related Search:

(3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)aMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2- 2-(((3aR,4S,6R,6aS)-6-(7-aMino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2-diMethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol Ticagrelor Sulfone 2-((3aS,4R,6S,6aR)-4-aminotetrahydro-3aH-spiro[cyclopenta[d][1,3]dioxole-2,1'-cyclopentane]-6-yloxy)ethanol oxalic acid salt Ticagrelor iMpurity
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)aMino)-5-(propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol TICAGRELOR 2-((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)ethanol L-tataric acid 4,6-dichloro-2-propylthiopyrimidine-5-amine (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
1-Acetyladamantane Intermediate (1R trans)-2-(3,4-difluorophenyl)cyclopropane amine. HCl Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[[5-aMino-6-chloro-2-(propylthio)-4-pyriMidinyl]aMino]tetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]- ethyCyclopropanamine, 2-(3,4-difluorophenyl)-, (1R,2S)- (REACH) (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide
(1R trans)-2-(3,4-difluorophenyl)cyclopropane amine CarbaMicacid,N-[(3aS,4R,6S,6aR)-tetrahydro-6-hydroxy-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-yl]-,phenylMethyl ester 4,6-Dichloro-5-nitro-2-propylthiopyrimidine

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6-AMinotetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-ol (3aS,4R,6S,6aR)-6-Hydroxy-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-amine Ticagrelor Related Compound 1 ((3aR, 4S, 6R, 6aS)-6-Aminotetrahydro-2,2-Dimethyl-4H-Cyclopenta-1.3-dioxol-4-ol) (3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-ol (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-… (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol(Ticagrelor Intermediate) 6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol - A10118 Ticagrelor Related Compound 1 (3aR,4S,6R,6aS)-6-Amino-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol Ticagrelor Impurity 102 (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol 4H-Cyclopenta-1,3-dioxol-4-ol, 6-aminotetrahydro-2,2-dimethyl-, (3aR,4S,6R,6aS)- TICAGRELOR int Ticagrelor-24 Ticagrelor impurity 35/(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol 2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol Ticagrelor Related Compound 1（rac-tartaric acid dibenzoate） (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol ISO 9001：2015 REACH (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta... 3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d]dioxol-4-ol (3AR, 4S, 6R, 6AS) -6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenteno-1,3-dioxocyclopentane-4-ol N-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-N-(9-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-2-(propylthio)-9H-purin-6-yl)nitrous amide (3aR,4S,6R,6aS)-6-amino-tetrahydro-2,2-dimethyl-3aH-cyclopenta[d][1,3]dioxol-4-ol (3AR,4S,6R,6AS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxolan-4-ol (3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol (Ticagrelor Impurity) (3aR,4S,6R,6aS)-6-aMino-2,2-diMethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol 155899-66-4 155899-66-4