N3-PEG4-tBu
- CAS No.
- 581066-04-8
- Chemical Name:
- N3-PEG4-tBu
- Synonyms
- N3-PEG4-tBu;N3-PEG4-tBul;Azido-PEG4-Boc;Azido-PEG4-COOtBu;N3-PEG4-CH2CH2COOtBu;Azido-PEG4-tBu Ester;Azido-PEG4-tButly ester;Azido-PEG4-CH2CH2COOtBu;N3-?PEG4-?t-?butyl ester;Azido-PEG5-t-butyl ester
- CBNumber:
- CB72546987
- Molecular Formula:
- C15H29N3O6
- Molecular Weight:
- 347.40726
- MDL Number:
- MFCD18916988
- MOL File:
- 581066-04-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| N3-PEG4-tBu | FP73087 | 100mg | $250 |
| N3-PEG4-tBu | FP73087 | 50mg | $250 |
| N3-PEG4-tBu | FP73087 | 250mg | $307.5 |
| N3-PEG4-tBu | FP73087 | 500mg | $530 |
| N3-PEG4-tBu | FP73087 | 1000mg | $920 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
N3-PEG4-tBu price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FP73087 | N3-PEG4-tBu | 581066-04-8 | 100mg | $250 | 2026-06-04 | Buy |
| Biosynth | FP73087 | N3-PEG4-tBu | 581066-04-8 | 50mg | $250 | 2026-06-04 | Buy |
| Biosynth | FP73087 | N3-PEG4-tBu | 581066-04-8 | 250mg | $307.5 | 2026-06-04 | Buy |
| Biosynth | FP73087 | N3-PEG4-tBu | 581066-04-8 | 500mg | $530 | 2026-06-04 | Buy |
| Biosynth | FP73087 | N3-PEG4-tBu | 581066-04-8 | 1000mg | $920 | 2026-06-04 | Buy |
N3-PEG4-tBu Chemical Properties,Uses,Production
Description
Azido-PEG4-t-butyl ester is a click chemistry linker containing an azide (N3) and a t-butyl ester moiety. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group is reactive toward alkyne, BCN, DBCO via Click Chemistry . The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N3-PEG4-tBu Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 +8617350879715 | changaiwei@sinopeg.com | China | 1125 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9949 | 58 |
View Lastest Price from N3-PEG4-tBu manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-02-05 | tert-butyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate
581066-04-8
|
1g | 98% | 581066-04-8 | XIAMEN SINOPEG BIOTECH CO., LTD. | ||
![]() |
2025-06-07 | azido-PEG4-t-Butyl ester
581066-04-8
|
5g | >98.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
-

- tert-butyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate
581066-04-8
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-

- azido-PEG4-t-Butyl ester
581066-04-8
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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