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Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate

CAS No.
30062-34-1
Chemical Name:
Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Synonyms
methyl 6-hydroxypicolinate;6-Methoxycarbonyl-2-pyridone;methyl 6-oxo-1H-pyridine-2-carboxylate;methyl 6-hydroxypicolinate hydrochloride;Methyl -oxo-1,6-dihydropyridine-2-carboxylate;Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate;Methvl 6-oxo-1.6-dihydropvridine-2-carboxylate;2-Pyridinecarboxylic acid, 1,6-dihydro-6-oxo-, methyl ester;Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate, methyl 6-hydroxypyridine-2-carboxylate
CBNumber:
CB72549665
Molecular Formula:
C7H7NO3
Molecular Weight:
153.14
MDL Number:
MFCD17015470
MOL File:
30062-34-1.mol
MSDS File:
SDS
Last updated:2026-05-28 03:57:40
Product description Number Pack Size Price
Methyl 6-hydroxypyridine-2-carboxylate 98% OR955459 250mg $21
Methyl 6-hydroxypyridine-2-carboxylate 98% OR955459 1g $24
Methyl 6-hydroxypyridine-2-carboxylate 98% OR955459 5g $62
Methyl 6-hydroxypyridine-2-carboxylate 98% OR955459 25g $293
Methyl 6-hydroxypyridine-2-carboxylate 98% OR955459 100g $921
More product size

Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate Properties

Melting point 109-110 °C
Boiling point 367.6±42.0 °C(Predicted)
Density 1.263±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 8.83±0.10(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C7H7NO3/c1-11-7(10)5-3-2-4-6(9)8-5/h2-4H,1H3,(H,8,9)
InChIKey GJLWQAUHCDNAEK-UHFFFAOYSA-N
SMILES C1(C(OC)=O)NC(=O)C=CC=1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P501-P261-P272-P280-P302+P352-P362+P364-P333+P313
HS Code  2933399990

Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR955459 Methyl 6-hydroxypyridine-2-carboxylate 98% 30062-34-1 250mg $21 2026-06-04 Buy
Apolloscientific OR955459 Methyl 6-hydroxypyridine-2-carboxylate 98% 30062-34-1 1g $24 2026-06-04 Buy
Apolloscientific OR955459 Methyl 6-hydroxypyridine-2-carboxylate 98% 30062-34-1 5g $62 2026-06-04 Buy
Apolloscientific OR955459 Methyl 6-hydroxypyridine-2-carboxylate 98% 30062-34-1 25g $293 2026-06-04 Buy
Apolloscientific OR955459 Methyl 6-hydroxypyridine-2-carboxylate 98% 30062-34-1 100g $921 2026-06-04 Buy
Product number Packaging Price Buy
OR955459 250mg $21 Buy
OR955459 1g $24 Buy
OR955459 5g $62 Buy
OR955459 25g $293 Buy
OR955459 100g $921 Buy

Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate Chemical Properties,Uses,Production

Uses

Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate, as an important pharmaceutical intermediate and fine chemical raw material, has a wide range of applications and a broad market prospect. In the pharmaceutical field, 2-pyridinemethanol, as an important pharmaceutical intermediate, can be used to synthesize bisacodyl, a blood transfusion drug, and is also a raw material for synthesizing pralidoxime, an organophosphate antidote.

Synthesis

Methanol

67-56-1

6-Hydroxypicolinic acid

19621-92-2

Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate

30062-34-1

Step 1: Synthesis of methyl 6-hydroxypyridine-2-carboxylate. 6-Hydroxypyridine-2-carboxylic acid (13.0 g, 93.5 mmol) was dissolved in methanol (150 mL) at room temperature and a dioxane solution of 4N HCl (10 mL) was slowly added. The reaction mixture was stirred at room temperature for 48 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure to afford methyl 6-hydroxypyridine-2-carboxylate (13 g, 90% yield) as a white solid.

References

[1] Patent: WO2004/37808, 2004, A1. Location in patent: Page 19-20
[2] Patent: WO2014/154727, 2014, A1. Location in patent: Page/Page column 38; 52
[3] Patent: US2014/296239, 2014, A1. Location in patent: Paragraph 0097; 0098
[4] Patent: WO2014/154726, 2014, A1. Location in patent: Page/Page column 38-39
[5] Patent: US2014/296296, 2014, A1. Location in patent: Paragraph 0106; 0107

67-56-1
19621-92-2
30062-34-1
Synthesis of Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate from Methanol and 6-Hydroxypicolinic acid

Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 77)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 3961 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29766 58
Hefei TNJ Chemical Industry Co.,Ltd.
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HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Aladdin Scientific
tp@aladdinsci.com United States 54746 58
Suzhou ARTK Medchem Co., Ltd.
+86-18168183658 sales1@artkmedchem.com China 39007 58
HANGZHOU HAILAN CHEMICAL CO.,LTD.
+86-57156122185 +86-15967590394 sales@hailan-chem.com China 2998 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16505 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131885 58
Record Tech (Shanghai) Co., LTD 13761627472 183009664@qq.com China 661 62

View Lastest Price from Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate pictures 2024-07-18 Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate
30062-34-1
$1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate pictures 2019-07-06 Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate
30062-34-1
$1.00 1kg 98% 200KG Career Henan Chemical Co

Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate Spectrum

Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate 6-Methoxycarbonyl-2-pyridone methyl 6-hydroxypicolinate methyl 6-hydroxypicolinate hydrochloride methyl 6-oxo-1H-pyridine-2-carboxylate 2-Pyridinecarboxylic acid, 1,6-dihydro-6-oxo-, methyl ester Methyl -oxo-1,6-dihydropyridine-2-carboxylate Methvl 6-oxo-1.6-dihydropvridine-2-carboxylate Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate, methyl 6-hydroxypyridine-2-carboxylate 30062-34-1