ChemicalBook >> CAS DataBase List >>Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-

Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-

CAS No.
168682-53-9
Chemical Name:
Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
Synonyms
CS-1110;Ezatiostat;Terrapin 199;Ezatiostat, >96%;Ezatiostat, >=98%;TER199(free base);Ezatiostat (TER199);Ezatiostat salt free;Ezatiostat 168682-53-9;Ezatiostat, 10 mM in DMSO
CBNumber:
CB72563432
Molecular Formula:
C27H35N3O6S
Molecular Weight:
529.65
MDL Number:
MFCD27982957
MOL File:
168682-53-9.mol
Last updated:2025-07-25 23:32:35

Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- Properties

Melting point >94°C (dec.)
Boiling point 749.7±60.0 °C(Predicted)
Density 1.216±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 12?+-.0.46(Predicted)
form Solid
color White to Off-White
InChIKey FXTMNDVNPLUYKX-OKIYALLLNA-N
SMILES C(OCC)(=O)[C@@H](C1=CC=CC(CC)=C1)N(C(=O)CC[C@@H](C(O)=O)N)C(=O)[C@H](CSCC1=CC=CC=C1)N |&1:5,19,26,r|
FDA UNII 057D10I8S8
UNSPSC Code 12352200
NACRES NA.77

Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1081 Ezatiostat ≥98% (HPLC) 168682-53-9 5 mg $136 2025-07-31 Buy
Sigma-Aldrich SML1081 Ezatiostat ≥98% (HPLC) 168682-53-9 25 mg $550 2025-07-31 Buy
Cayman Chemical 16248 Ezatiostat ≥98% 168682-53-9 1mg $32 2024-03-01 Buy
Cayman Chemical 16248 Ezatiostat ≥98% 168682-53-9 5mg $109 2024-03-01 Buy
Cayman Chemical 16248 Ezatiostat ≥98% 168682-53-9 10mg $199 2024-03-01 Buy
Product number Packaging Price Buy
SML1081 5 mg $136 Buy
SML1081 25 mg $550 Buy
16248 1mg $32 Buy
16248 5mg $109 Buy
16248 10mg $199 Buy

Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- Chemical Properties,Uses,Production

Description

Ezatiostat is an inhibitor of glutathione S-transferase pi 1-1 (GSTP1-1; Ki = 0.4 μM). It is selective for GSTP1-1 over GSTα and GSTμ family GSTs (Kis = 20-75 μM). Ezatiostat also inhibits the protein-protein interaction between GSTP1-1 and JNK1. In vivo, ezatiostat (75 mg/kg) increases the number of circulating white blood cells in Gstp1 wild-type, but not Gstp1-/-, mice.

Uses

Ezatiostat is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1, the most prevalent Glutathione S-transferases (GST) isozyme in nonhepatic tissues, catalytic activity with minimal effect on the related GSTα and -μ families.

in vivo

Administration of Ezatiostat (TLK199), stimulates both lymphocyte production and bone marrow progenitor (colony-forming unit-granulocyte macrophage) proliferation, but only in glutathione S-transferase P1-1 (GSTP1+/+) and not in GSTP1-/-animals[2].

target

Gutathione S-transferase

Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 116)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Shanghai Longyu Biotechnology Co., Ltd.
+8619521488211 info@longyupharma.com China 2556 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29804 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32376 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
LEAP CHEM CO., LTD.
+86-852-30606658 19957148339; market18@leapchem.com China 24727 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 38838 58

View Lastest Price from Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ezatiostat pictures 2025-07-24 Ezatiostat
168682-53-9
US $54.00-179.00 / mg 97.95% 10g TargetMol Chemicals Inc.
Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- pictures 2020-02-14 Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
168682-53-9
US $7.00 / KG 1KG 99% 100KG Career Henan Chemical Co
  • Ezatiostat pictures
  • Ezatiostat
    168682-53-9
  • US $54.00-179.00 / mg
  • 97.95%
  • TargetMol Chemicals Inc.

Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- Spectrum

168682-53-9(Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-)Related Search:

Ezatiostat, >96% CS-1110 TER 199; TLK-199; TELINTRA (S)-ETHYL 2-AMINO-5-((R)-3-(BENZYLTHIO)-1-((R)-2-ETHOXY-2-OXO-1-PHENYLETHYLAMINO)-1-OXOPROPAN-2-YLAMINO)-5-OXOPENTANOATE (2R)-L-gamma-Glutamyl-S-(phenylmethyl)-L-cysteinyl-2-phenylglycine 1,3-diethyl ester Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- Ezatiostat Terrapin 199 Ezatiostat, >=98% Ezatiostat (TER199) Ezatiostat TFA (free base) TER199(free base) Glycine, L-γ-glutamyl-S-(phenylmethyl)-L-cysteinyl-2-phenyl-, 1,3-diethyl ester, (2R)- Ethyl N5-((R)-3-(benzylthio)-1-(((R)-2-ethoxy-2-oxo-1-phenylethyl)amino)-1-oxopropan-2-yl)-L-glutaminate Ezatiostat salt free Ezatiostat 168682-53-9 Ezatiostat(TER199, TLK199) Ezatiostat, 10 mM in DMSO (S)-ethyl 2-amino-5-(((R)-3-(benzylthio)-1-(((S)-2-ethoxy-2-oxo-1-phenylethyl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoate 168682-53-9 C27H35N3O6S