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Isophorone oxide

CAS No.
10276-21-8
Chemical Name:
Isophorone oxide
Synonyms
ISOPHORONE OXIDE;)-Epoxyisophorone;IsophoroneOxide>Isophorone oxide 99%;Oxidation of Isophorone;2,3-Epoxy-3,5,5-trimethylcyclohexanone;3,5,5-TriMecthyl-2,3-epoxy cyclohexanon;2,3-Epoxy-3,5,5-trimethyl-1-cyclohexanone;3,5,5-Trimethyl-2,3-epoxy-1-cyclohexanone;2,3-Epoxy-3,5,5-trimethylcyclohexane-1-one
CBNumber:
CB7257935
Molecular Formula:
C9H14O2
Molecular Weight:
154.21
MDL Number:
MFCD00085465
MOL File:
10276-21-8.mol
MSDS File:
SDS
Last updated:2025-09-25 17:15:13
Product description Number Pack Size Price
Isophorone oxide 99% 404675 5g $255
Isophorone Oxide >97.0%(GC) I0805 5g $64
Isophorone Oxide >97.0%(GC) I0805 25g $185
Isophorone oxide I821993 250mg $45
Oxoisophorone S565 1g $27
More product size

Isophorone oxide Properties

Boiling point 75-76 °C/6 mmHg (lit.)
Density 0.994 g/mL at 25 °C (lit.)
refractive index n20/D 1.453(lit.)
Flash point 182 °F
storage temp. Sealed in dry,Room Temperature
form clear liquid
color Colorless to Light yellow to Light orange
UNSPSC Code 12162002
NACRES NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H227
Precautionary statements  P501-P261-P270-P210-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312-P403+P235
Hazard Codes  Xn
Risk Statements  20/21/22-40
Safety Statements  23-36
RIDADR  UN 1993 / PGIII
WGK Germany  3
HS Code  29142990
Excepted Quantities Non-Hazardous
NFPA 704
2
2 0

Isophorone oxide price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 404675 Isophorone oxide 99% 10276-21-8 5g $255 2023-06-20 Buy
TCI Chemical I0805 Isophorone Oxide >97.0%(GC) 10276-21-8 5g $64 2025-07-31 Buy
TCI Chemical I0805 Isophorone Oxide >97.0%(GC) 10276-21-8 25g $185 2025-07-31 Buy
TRC I821993 Isophorone oxide 10276-21-8 250mg $45 2021-12-16 Buy
AK Scientific S565 Oxoisophorone 10276-21-8 1g $27 2021-12-16 Buy
Product number Packaging Price Buy
404675 5g $255 Buy
I0805 5g $64 Buy
I0805 25g $185 Buy
I821993 250mg $45 Buy
S565 1g $27 Buy

Isophorone oxide Chemical Properties,Uses,Production

Uses

Isophorone oxide could be rearranged to 3,5,5-trimethyl-1,2-cyclohexanedione and 2-formyl-2,4,4-trimethylcyclopentanone with high conversions and selectivities using zeolites and montmorillonite K10 as catalysts.

Synthesis

In a three-necked flask equipped with a dropping funnel, a mechanical stirrer, and a thermometer, a solution of 55.2 g (0.4 mol) of isophorone and 115 ml (1.2 mol) of 30% aqueous hydrogen peroxide in 400 ml of methanol. After the contents of the flask have been cooled to 15 ℃ using an ice bath, 33 ml (0.2 mol) of 6N aqueous sodium hydroxide is added, dropwise and with stirring, over 1 hour. During the addition, the temperature of the reaction mixture is maintained at 15–20℃ with a bath of cold water. After the addition is complete, the resulting mixture is stirred for 3 hours as the reaction mixture temperature is maintained at 20–25℃. The reaction mixture is then poured into 500 ml. of water, and the resulting mixture is extracted with two 400-ml portions of ether. The combined extracts are washed with water and dried over anhydrous magnesium sulfate. After the bulk of the ether has been removed by distillation (or flash distillation) through a 30-cm. Vigreux column at atmospheric pressure, the residual liquid is distilled through the Vigreux column under reduced pressure. The yield of isophorone oxide is 43–44.5 g. (70–72%).

References

[1] J. A. Elings, R. Sheldon, H. Lempers. “Zeolite-catalysed rearrangement of isophorone oxide.” Studies in Surface Science and Catalysis 15 1 (1997): 1165–1172.

78-59-1
10276-21-8
56621-35-3
1125-21-9
14203-59-9
Synthesis of Isophorone oxide from Isophorone
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View Lastest Price from Isophorone oxide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4,4,5A-TRIMETHYLPERHYDRO-1-BENZOXIREN-2-ONE pictures 2025-10-11 4,4,5A-TRIMETHYLPERHYDRO-1-BENZOXIREN-2-ONE
10276-21-8
US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
4,4,5A-TRIMETHYLPERHYDRO-1-BENZOXIREN-2-ONE pictures 2025-08-08 4,4,5A-TRIMETHYLPERHYDRO-1-BENZOXIREN-2-ONE
10276-21-8
US $0.00 / KG 1KG 99% 50000KG/month Sichuan Zhuoyu Yantang Technology Co., Ltd.
4,4,5A-TRIMETHYLPERHYDRO-1-BENZOXIREN-2-ONE pictures 2025-04-04 4,4,5A-TRIMETHYLPERHYDRO-1-BENZOXIREN-2-ONE
10276-21-8
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
ISOPHORONE OXIDE 4,4,5A-TRIMETHYLPERHYDRO-1-BENZOXIREN-2-ONE 2,3-Epoxy-3,5,5-trimethyl-1-cyclohexanone 2,3-Epoxy-3,5,5-trimethylcyclohexane-1-one 7-Oxabicyclo[4.1.0]heptan-2-one, 4,4,6-triMethyl- 3,5,5-Trimethyl-2,3-epoxy-1-cyclohexanone 2,3-Epoxy-3,5,5-trimethyl-1-cyclohexanone 4,4,6-Trimethyl-7-oxabicyclo[4.1.0]heptan-2-one 3,5,5-TriMecthyl-2,3-epoxy cyclohexanon )-Epoxyisophorone 7-Oxabicyclo[4.1.0]heptan-2-one,4,4,6-trimethyl-(6CI,7CI,8CI,9CI) 2,3-Epoxy-3,5,5-trimethylcyclohexanone Oxidation of Isophorone Isophorone oxide 99% IsophoroneOxide> 3,5,5-Trimethyl-2,3-epoxy-1-cyclohexanone 4,4,5A-TRIMETHYLPERHYDRO-1-BENZOXIREN-2-ONE USP/EP/BP 10276-21-8 Epoxide Monomers Monomers Polymer Science EPOXYDE