S32826
- CAS No.
- 1096770-84-1
- Chemical Name:
- S32826
- Synonyms
- OUXAHVRWFHOKHY-UHFFFAOYSA-N;S32826 disodium salt hydrate;4-Tetradecanamidobenzylphosphonic acid;[4-(Tetradecanoylamino)benzyl]phosphonic acid;p-((4-((1-Oxotetradecyl)amino)phenyl)methyl)-phosphonic acid;Phosphonic acid, P-[[4-[(1-oxotetradecyl)amino]phenyl]methyl]-;[4-(Tetradecanoylamino)benzyl]phosphonic acid disodium salt hydrate
- CBNumber:
- CB72592393
- Molecular Formula:
- C21H36NO4P
- Molecular Weight:
- 397.49
- MDL Number:
- MFCD12761322
- MOL File:
- 1096770-84-1.mol
- MSDS File:
- SDS
| Density | 1.116±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | -20°C |
| solubility | H2O: ≥10mg/mL |
| form | powder |
| pka | 2.24±0.10(Predicted) |
| color | white |
| Water Solubility | H2O: ≥10mg/mL |
| InChI | 1S/C21H36NO4P.2Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-21(23)22-20-16-14-19(15-17-20)18-27(24,25)26;;/h14-17H,2-13,18H2,1H3,(H,22,23)(H2,24,25,26);;/q;2*+1/p-2 |
| InChIKey | DGRFALMFDGBLCP-UHFFFAOYSA-L |
| SMILES | [Na+].[Na+].CCCCCCCCCCCCCC(=O)Nc1ccc(CP([O-])([O-])=O)cc1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
S32826 price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S1825 | S32826 disodium salt hydrate ≥98% (HPLC) | 1096770-84-1 | 5mg | $191 | 2026-04-30 | Buy |
| Sigma-Aldrich | S1825 | S32826 disodium salt hydrate ≥98% (HPLC) | 1096770-84-1 | 25mg | $737 | 2026-04-30 | Buy |
| Cayman Chemical | 13664 | S32826 ≥98% | 1096770-84-1 | 1mg | $42 | 2026-04-30 | Buy |
| Cayman Chemical | 13664 | S32826 ≥98% | 1096770-84-1 | 5mg | $132 | 2026-04-30 | Buy |
| Cayman Chemical | 13664 | S32826 ≥98% | 1096770-84-1 | 10mg | $242 | 2026-04-30 | Buy |
S32826 Chemical Properties, Uses, Production
Uses
S32826, a potent inhibitor of autotaxin (ATX), may be used to identify and characterize the lyso-phospholipase D (lysoPLD, ATX) involved in bioactive lyso-phosphatidic acid (LPA) formation. S32826 may be used to help determine the role of ATX in malignant cell processes such as tumorigenesis, invasion, and metastases; cardia bifida and atherosclerosis.
Definition
ChEBI: P-[[4-[(1-oxotetradecyl)amino]phenyl]methyl]-phosphonic acid is an anilide.
Biological Activity
S32826 is a potent inhibitor of autotaxin. Autotaxin is a newly discovered lyso-phospholipase D (lysoPLD). Autotaxin and lyso-phosphatidic acid (LPA) have been associated with early cancer progression and motility of cancer cells as well as with metastasis. Because of localization (adipose tissue), the enzyme might play an important role in diabetes and obesity. Autotaxin might be the only source of LPA. S32826 is the strongest inhibitor of autotaxin reported. The compound shows activity in cellular or ex vivo models.
S32826 Preparation Products And Raw materials
Raw materials
Preparation Products
S32826 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Changyan Chem & Tech Co., Ltd. | 021-20242659 18930833303 | sales@changyanchem.cn | China | 4998 | 55 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | shenlinxing@macklin.cn | China | 29676 | 58 |
| Absin Bioscience Inc. | 13761418683 | fengmj@univ-bio.com | China | 12045 | 58 |
