2-(3-Fluoro-2-nitrophenyl)acetic acid
- CAS No.
- 872141-25-8
- Chemical Name:
- 2-(3-Fluoro-2-nitrophenyl)acetic acid
- Synonyms
- 2-(3-Fluoro-2-nitrophenyl);3-Fluoro-2-nitrobenzeneacetic acid;Benzeneacetic acid, 3-fluoro-2-nitro-;2-(3-Fluoro-2-nitrophenyl)acetic acid
- CBNumber:
- CB72631599
- Molecular Formula:
- C8H6FNO4
- Molecular Weight:
- 199.14
- MDL Number:
- MFCD13192267
- MOL File:
- 872141-25-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(3-Fluoro-2-nitrophenyl)acetic acid | 119761 | 1.00g | $74 |
| 2-(3-Fluoro-2-nitrophenyl)acetic acid | 119761 | 5.00g | $228 |
| 2-(3-Fluoro-2-nitrophenyl)acetic acid | 119761 | 25.00g | $802 |
| 2-(3-Fluoro-2-nitrophenyl)acetic acid 97% | F48053 | 100mg | $40 |
| 2-(3-Fluoro-2-nitrophenyl)acetic acid 97% | F48053 | 250mg | $60 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H335-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
2-(3-Fluoro-2-nitrophenyl)acetic acid price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 119761 | 2-(3-Fluoro-2-nitrophenyl)acetic acid | 872141-25-8 | 1.00g | $74 | 2026-05-18 | Buy |
| Matrix Scientific | 119761 | 2-(3-Fluoro-2-nitrophenyl)acetic acid | 872141-25-8 | 5.00g | $228 | 2026-05-18 | Buy |
| Matrix Scientific | 119761 | 2-(3-Fluoro-2-nitrophenyl)acetic acid | 872141-25-8 | 25.00g | $802 | 2026-05-18 | Buy |
| Synthonix | F48053 | 2-(3-Fluoro-2-nitrophenyl)acetic acid 97% | 872141-25-8 | 100mg | $40 | 2026-05-06 | Buy |
| Synthonix | F48053 | 2-(3-Fluoro-2-nitrophenyl)acetic acid 97% | 872141-25-8 | 250mg | $60 | 2026-05-06 | Buy |
2-(3-Fluoro-2-nitrophenyl)acetic acid Chemical Properties,Uses,Production
Uses
(3-Fluoro-2-nitrophenyl)acetic acid
Synthesis
872141-24-7
872141-25-8
General procedure for the synthesis of 2-(3-fluoro-2-nitrophenyl)acetic acid from dimethyl 2-(3-fluoro-2-nitrophenyl)malonate: dimethyl 2-(3-fluoro-2-nitrophenyl)malonate (2.53 g, 9.33 mmol) was suspended in water (20 mL). Concentrated hydrochloric acid (20 mL, 653 mmol) was slowly added to this suspension. The reaction mixture was heated to reflux and maintained under stirring for 5 hours. After completion of the reaction, the mixture was cooled to room temperature. The mixture was extracted twice with ether and the aqueous phase was discarded. The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated to dryness. The residue was recrystallized by a 5:1 solvent mixture of hexane and ethyl acetate. The precipitated solid was collected, washed with hexane and subsequently dried under vacuum to afford the target compound 2-(3-fluoro-2-nitrophenyl)acetic acid as a white solid in 90% yield.1H NMR (300 MHz, chloroform-d) δ ppm: 3.85 (s, 2H), 7.08-7.19 (m, 1H), 7.20-7.28 (m, 1H), 7.38 -7.55 (m, 1H).
References
[1] Patent: US2007/259851, 2007, A1. Location in patent: Page/Page column 114-115
[2] Patent: US2011/59954, 2011, A1. Location in patent: Page/Page column 94
[3] Journal of Medicinal Chemistry, 2008, vol. 51, # 6, p. 1861 - 1873
[4] Patent: US2006/9509, 2006, A1. Location in patent: Page/Page column 9
2-(3-Fluoro-2-nitrophenyl)acetic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42934 | 64 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18209 | 56 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8026 | 55 |
| Jalor-Chem co.,LTD | 0510-0510-86396359 13382276200 | sales@jalor-chem.com | China | 999 | 56 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
