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(S)-(-)-WARFARIN

(S)-(-)-WARFARIN Structure
(S)-(-)-WARFARIN structure
CAS No.
5543-57-7
Chemical Name:
(S)-(-)-WARFARIN
Synonyms
Warfarin,R-;(S)-WARFARIN;(S)-(-)-WARFARIN;Warfarin S-Isomer;Warfarin Impurity 17;S-(?)-Warfarin >,99;Warfarin Impurity 17（Warfarin S-Isomer）;s-(-)-3-acetonybenzyl)-4-hydroxycoumarin;S-(-)-3-(ACETONYLBENZYL)-4-HYDROXYCOUMARIN;Warfarin sodium Impurity 23 ((S)-Warfarin)
CBNumber:
CB7267099
Molecular Formula:
C19H16O4
Molecular Weight:
308.33
MDL Number:
MFCD00272381
MOL File:
5543-57-7.mol
MSDS File:
SDS
Last updated:2025-08-21 22:16:43
Product description Number Pack Size Price
(S)-(?)-Warfarin ≥97% (HPLC) UC214 5mg $918
(S)-(?)-Warfarin ≥97% (HPLC) UC214 10mg $1660
(-)-Warfarin ≥98% 13531 1mg $74
(-)-Warfarin ≥98% 13531 5mg $241
(-)-Warfarin ≥98% 13531 10mg $444
More product size
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(S)-(-)-WARFARIN Properties

Melting point ≥170 °C
storage temp. 2-8°C
solubility DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid
color white to pale yellow
CAS DataBase Reference 5543-57-7(CAS DataBase Reference)
FDA UNII HP31W7FNP4
UNSPSC Code 12161501
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H300+H310+H330-H360D-H372-H411
Precautionary statements  P202-P264-P273-P280-P302+P352+P310-P304+P340+P310
Hazard Codes  T
Risk Statements  61-48/25-52/53
Safety Statements  53-45-61
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
NFPA 704
0
4 0

(S)-(-)-WARFARIN price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich UC214 (S)-(?)-Warfarin ≥97% (HPLC) 5543-57-7 5mg $918 2024-03-01 Buy
Sigma-Aldrich UC214 (S)-(?)-Warfarin ≥97% (HPLC) 5543-57-7 10mg $1660 2024-03-01 Buy
Cayman Chemical 13531 (-)-Warfarin ≥98% 5543-57-7 1mg $74 2024-03-01 Buy
Cayman Chemical 13531 (-)-Warfarin ≥98% 5543-57-7 5mg $241 2024-03-01 Buy
Cayman Chemical 13531 (-)-Warfarin ≥98% 5543-57-7 10mg $444 2024-03-01 Buy
Product number Packaging Price Buy
UC214 5mg $918 Buy
UC214 10mg $1660 Buy
13531 1mg $74 Buy
13531 5mg $241 Buy
13531 10mg $444 Buy

(S)-(-)-WARFARIN Chemical Properties,Uses,Production

Description

(–)-Warfarin is a component of (±)-warfarin . It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. In vivo, (–)-warfarin slows formation of the prothrombin complex and exhibits 6.6-fold more potent anticoagulant activity than (+)-warfarin in rats. (–)-Warfarin is primarily metabolized by the cytochrome P450 (CYP) isoform CYP2C9 and genetic polymorphisms in this enyzme, as well as other compounds metabolized by CYP2C9, increase the potential for catastrophic bleeding complications. Formulations containing warfarin have been used to treat and prevent blood clots in atrial fibrillation, heart valve replacement, venous thrombosis, and pulmonary embolism.

Chemical Properties

White Solid

Uses

The S-(-)-form of Warfarin (W498500). Coumarin anticoagulant.

Uses

(S)-(?)-Warfarin has been used in cell cultures.

Definition

ChEBI: (S)-warfarin is a 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one that has (S)-configuration (the racemate is warfarin, an anticoagulant drug and rodenticide). It is a conjugate acid of a (S)-warfarin(1-). It is an enantiomer of a (R)-warfarin.

General Description

Warfarin is an antagonist of vitamin K. It is an oral coumarin anticoagulant.

Biochem/physiol Actions

Warfarin is used to regulate and inhibit thromboembolic disorders. The CYP2C9 (cytochrome P450 family 2 subfamily C member 9)?protein plays a major role in the inactivation of potent S-warfarin.

References

[1] A. BRECKENRIDGE  M. L O. The plasma half lives and the pharmacological effect of the enantiomers of warfarin in rats[J]. Life sciences, 1972, 11 7: Pages 337-345. DOI: 10.1016/0024-3205(72)90073-2
[2] AYAKA SHIOZAWA . Effects of acid and lactone forms of statins on S-warfarin 7-hydroxylation catalyzed by human liver microsomes and recombinant CYP2C9 variants (CYP2C9.1 and CYP2C9.3)[J]. Drug Metabolism and Pharmacokinetics, 2021, 36: Article 100364. DOI: 10.1016/j.dmpk.2020.10.003

(S)-(-)-WARFARIN Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-(-)-WARFARIN Suppliers

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569266 +86-17392581500 1015@dideu.com China 3965 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11922 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43339 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
QUALITY CONTROL SOLUTIONS LTD. 		+86-0755-66853366 +86-13670046396 export03@qcsrm.com China 24342 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32343 55
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Shaanxi Dideu Medichem Co. Ltd 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
China National Standard Pharmaceutical Corporation Limited 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Amadis Chemical Company Limited 		58
QUALITY CONTROL SOLUTIONS LTD. 		58
Mainchem Co., Ltd. 55

View Lastest Price from (S)-(-)-WARFARIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-Warfarin pictures 2025-08-21 (S)-Warfarin
5543-57-7
 US $390.00-2330.00 / mg 10g TargetMol Chemicals Inc.
(S)-(-)-WARFARIN pictures 2024-10-22 (S)-(-)-WARFARIN
5543-57-7
 US $0.37 / KG 1KG 99% 10kg/100kg Career Henan Chemica Co
  • (S)-Warfarin pictures
  • (S)-Warfarin
    5543-57-7
  • US $390.00-2330.00 / mg
  • TargetMol Chemicals Inc.

5543-57-7((S)-(-)-WARFARIN)Related Search:

Warfarin 4-Hydroxycoumarin 4,4'-(Disulfanediyl)bis(2,6-di-tert-butylphenol) (S)-8-Hydroxy Warfarin 6-HYDROXYWARFARIN
(R)-6-Hydroxy Warfarin 3-(o-Hydroxyphenyl)-5-phenyl-2-cyclohexen-1-one Benzalacetone 3-[α-(2-Hydroxypropyl)benzyl]-4-hydroxycouMarin (R)-7-Hydroxy Warfarin
7-HYDROXYWARFARIN (S)-6-Hydroxy Warfarin Warfarin Impurity 1 8-HYDROXYWARFARIN 2,6-Di-tert-butyl-4-mercaptophenol
7-HYDROXYWARFARIN (R)-(+)-WARFARIN,(R)-WARFARIN (R)-8-HYDROXY WARFARIN

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Coumarin, 3-(a-acetonylbenzyl)-4-hydroxy-, (S)-(-)- (8CI) 4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-chromen-2-one S-(-)-3-Acetonybenzyl)-4-hydroxycoumarin, S-(-)-4-Hydroxy-3-(3-oxo-1-phenybutyl)-2H-1-benzopyran-2-one (-)-3-[(S)-1-Phenyl-3-oxobutyl]-4-hydroxycoumarin (-)-3-[(S)-α-Acetonylbenzyl]-4-hydroxycoumarin (-)-4-Hydroxy-3-[(S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one 2-hydroxy-3-(3-keto-1-phenyl-butyl)chromone 2-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-4-one 4-Hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one (S)-(-)-WARFARIN (S)-WARFARIN (S)-(+)-4-HYDROXY-3-(3-OXO-1-PHENYBUTYL)-2H-1-BENZOPYRAN-2-ONE S-(-)-4-HYDROXY-3-(3-OXO-1-PHENYBUTYL)-2H-1-BENZOPYRAN-2-ONE (S)-(+)-4-HYDROXY-3-(3-OXO-1-PHENYLBUTYL)-2H-1-BENZOPYRAN-2-ONE S-(-)-3-(ACETONYLBENZYL)-4-HYDROXYCOUMARIN (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone Warfarin,R- (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one 4-HYDROXY-3-((S)-3-OXO-1-PHENYL-BUTYL)-CHROMEN-2-ONE s-(-)-3-acetonybenzyl)-4-hydroxycoumarin 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, (S)- 2H-1-Benzopyran-2-one, 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]- (9CI) Warfarin S-Isomer Warfarin Impurity 17（Warfarin S-Isomer） Warfarin Impurity 17 S-(-)-WarfarinQ: What is S-(-)-Warfarin Q: What is the CAS Number of S-(-)-Warfarin Q: What is the storage condition of S-(-)-Warfarin Q: What are the applications of S-(-)-Warfarin Warfarin sodium Impurity 23 ((S)-Warfarin) S-(?)-Warfarin >,99 5543-57-7 C19H16O4 Intermediates & Fine Chemicals Pharmaceuticals Aromatics Chiral Reagents Heterocycles