Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-(trifluoroMethyl)-4H-chroMen-4-one

2-(trifluoroMethyl)-4H-chroMen-4-one

2-(trifluoroMethyl)-4H-chroMen-4-one Structure
2-(trifluoroMethyl)-4H-chroMen-4-one structure
CAS No.
151668-40-5
Chemical Name:
2-(trifluoroMethyl)-4H-chroMen-4-one
Synonyms
2-trifluoromethyl-4-chromone;2-(trifluoroMethyl)-4H-chroMen-4-one;2-(Trifluoromethyl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-(trifluoromethyl)-
CBNumber:
CB72703593
Molecular Formula:
C10H5F3O2
Molecular Weight:
214.14
MDL Number:
MFCD00761957
MOL File:
151668-40-5.mol
MSDS File:
SDS
Last updated:2026-05-28 05:43:48
Product description Number Pack Size Price
2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% PC910374 100mg $21
2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% PC910374 250mg $24
2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% PC910374 1g $36
2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% PC910374 5g $168
2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% PC910374 25g $816
Request For Quotation

2-(trifluoroMethyl)-4H-chroMen-4-one Properties

Melting point 95.0-95.7 °C
Boiling point 200.8±40.0 °C(Predicted)
Density 1.445±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2932990090

2-(trifluoroMethyl)-4H-chroMen-4-one price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC910374 2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% 151668-40-5 100mg $21 2026-06-04 Buy
Apolloscientific PC910374 2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% 151668-40-5 250mg $24 2026-06-04 Buy
Apolloscientific PC910374 2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% 151668-40-5 1g $36 2026-06-04 Buy
Apolloscientific PC910374 2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% 151668-40-5 5g $168 2026-06-04 Buy
Apolloscientific PC910374 2-(Trifluoromethyl)-4H-1-benzopyran-4-one 99% 151668-40-5 25g $816 2026-06-04 Buy
Product number Packaging Price Buy
PC910374 100mg $21 Buy
PC910374 250mg $24 Buy
PC910374 1g $36 Buy
PC910374 5g $168 Buy
PC910374 25g $816 Buy

2-(trifluoroMethyl)-4H-chroMen-4-one Chemical Properties,Uses,Production

Synthesis

2'-Hydroxyacetophenone

118-93-4

Trifluoroacetic anhydride

407-25-0

2-(trifluoroMethyl)-4H-chroMen-4-one

151668-40-5

General procedure for the synthesis of 2-trifluoromethyl-4H-chromen-4-one from 2'-hydroxyacetophenone and trifluoroacetic anhydride: 2'-hydroxyacetophenone (0.01 mol) was dissolved in trifluoroacetic anhydride (0.02 mol), followed by addition of pyridine (0.01 mol) to the solution. The reaction mixture was heated and stirred at 80 °C for 3 hours. After completion of the reaction, it was cooled to room temperature and the reaction mixture was treated with 1 M hydrochloric acid (5 mL) and dichloromethane (5 mL), followed by thorough washing with distilled water. The organic layer was dried with anhydrous sodium sulfate, the solvent was removed by rotary evaporator and the residue was vacuum dried. The target product 2-trifluoromethyl-4H-chromen-4-one was isolated from the starting material by fast column chromatography using a hexane solution of 10% ethyl acetate as eluent if necessary.

References

[1] Tetrahedron Letters, 2011, vol. 52, # 13, p. 1436 - 1440
[2] Tetrahedron, 2014, vol. 70, # 5, p. 1077 - 1083

2-(trifluoroMethyl)-4H-chroMen-4-one synthesis

118-93-4
407-25-0
151668-40-5
Synthesis of 2-(trifluoroMethyl)-4H-chroMen-4-one from 2'-Hydroxyacetophenone and Trifluoroacetic anhydride

2-(trifluoroMethyl)-4H-chroMen-4-one Preparation Products And Raw materials

Raw materials

Trifluoroacetic anhydride 2'-Hydroxyacetophenone 2-HYDROXYACETOPHENONE

Preparation Products

2-(trifluoroMethyl)-4H-chroMen-4-one Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
Blocksynth Pharmaceutical Technology Co.,Ltd 		0086-19817745290; +8619817745290 bd@blocksynth.com China 5973 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Suzhou ARTK Medchem Co., Ltd. 		+8618118463618 sales1@artkmedchem.com China 39021 58
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14100 59
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 3709 55
Shanghai Tombiopharma Chemical Co. Ltd. 13391076197 tombiopharma@163.com China 4987 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 89686 60
Aikon International Limited 025-66113011 19370895928 qzhang@aikonchem.com China 15393 58
Supplier Advantage
Blocksynth Pharmaceutical Technology Co.,Ltd 		58
Labnetwork lnc. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Suzhou ARTK Medchem Co., Ltd. 		58
PharmaBlock Sciences (Nanjing),Inc. 55
Adamas Reagent, Ltd. 59
Shanghai ChuangYan Chemical Technology Co., Ltd. 55
Shanghai Tombiopharma Chemical Co. Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Aikon International Limited 58

2-(trifluoroMethyl)-4H-chroMen-4-one Spectrum

2-(trifluoroMethyl)-4H-chroMen-4-one(151668-40-5)1HNMR2-(trifluoroMethyl)-4H-chroMen-4-one(151668-40-5)1HNMR2-(trifluoroMethyl)-4H-chroMen-4-one(151668-40-5)19FNMR
2-(trifluoroMethyl)-4H-chroMen-4-one 2-(Trifluoromethyl)-4H-1-benzopyran-4-one 2-trifluoromethyl-4-chromone 4H-1-Benzopyran-4-one, 2-(trifluoromethyl)- 151668-40-5