Acetone thiosemicarbazone
- CAS No.
- 1752-30-3
- Chemical Name:
- Acetone thiosemicarbazone
- Synonyms
- ATSC;ai3-22961[qr];IFLAB-BB F0777-0579;Acetonthiosemikarbazon;thiosemicarbazoneacetone;Thiosemicarbazone acetone;ACETONE THIOSEMICARBAZONE;ACETONE THIOSEMICARBAZIDE;Acetone semothiocarbazone;AcetorMe thios eMicarbazone
- CBNumber:
- CB7270907
- Molecular Formula:
- C4H9N3S
- Molecular Weight:
- 131.2
- MDL Number:
- MFCD00022153
- MOL File:
- 1752-30-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Acetone Thiosemicarbazone >97.0%(T) | A0059 | 25g | $24 |
| ACETONE THIOSEMICARBAZONE 95.00% | CHM0028272 | 10G | $1334.03 |
| Acetone Thiosemicarbazone | c08358 | 20mg | $30 |
| Acetone Thiosemicarbazone | c08358 | 50mg | $50 |
| More product size | |||
| Melting point | 174-175°C |
|---|---|
| Boiling point | 213.8±23.0 °C(Predicted) |
| Density | 1.142 (estimate) |
| refractive index | 1.5800 (estimate) |
| solubility | soluble in Acetone |
| pka | 12.20±0.70(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| InChI | InChI=1S/C4H9N3S/c1-3(2)6-7-4(5)8/h1-2H3,(H3,5,7,8) |
| InChIKey | FQUDPIIGGVBZEQ-UHFFFAOYSA-N |
| SMILES | N(C(N)=S)/N=C(/C)\C |
| CAS DataBase Reference | 1752-30-3(CAS DataBase Reference) |
| FDA UNII | C3U604L47F |
| NIST Chemistry Reference | 2-(1-Methylethylidene)hydrazinecarbothioamide(1752-30-3) |
| EPA Substance Registry System | Acetone thiosemicarbazide (1752-30-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300+H330-H312 | |||||||||
| Precautionary statements | P260-P264-P270-P271-P280-P284-P301+P310+P330-P302+P352+P312+P362+P364-P304+P340+P310-P403+P233-P405-P501 | |||||||||
| Risk Statements | 21-25-26 | |||||||||
| Safety Statements | 22-28-36/37/39 | |||||||||
| RIDADR | 2811 | |||||||||
| RTECS | AL7350000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2930.90.9250 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | I | |||||||||
| Hazardous Substances Data | 1752-30-3(Hazardous Substances Data) | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,23mg/kg (23mg/kg),BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Journal of Pharmacology and Experimental Therapeutics. Vol. 122, Pg. 110, 1958. | |||||||||
| NFPA 704 |
|
Acetone thiosemicarbazone price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A0059 | Acetone Thiosemicarbazone >97.0%(T) | 1752-30-3 | 25g | $24 | 2026-03-19 | Buy |
| American Custom Chemicals Corporation | CHM0028272 | ACETONE THIOSEMICARBAZONE 95.00% | 1752-30-3 | 10G | $1334.03 | 2021-12-16 | Buy |
| Aronis compounds | c08358 | Acetone Thiosemicarbazone | 1752-30-3 | 20mg | $30 | 2021-12-16 | Buy |
| Aronis compounds | c08358 | Acetone Thiosemicarbazone | 1752-30-3 | 50mg | $50 | 2021-12-16 | Buy |
Acetone thiosemicarbazone Chemical Properties,Uses,Production
Chemical Properties
Acetone thiosemicarbazide is a white to yellow crystalline solid with highly toxic.
Uses
Acetone thiosemicarbazone(ATSC) is a termination agent capable of rapidly halting reactions in PVC production processes, making it suitable for the suspension polymerisation of polyvinyl chloride resin.
Preparation
Synthesis of Acetone Thiosemicarbazone (ACTSC):Thiosemicarbazide (0.01 mol, 0.182 g) was dissolved in methanol (30 mL) under reflux at 50 °C. To this refluxing solution, a solution of acetone (0.1 mol, 0.87 mL) in methanol (30 mL) was added, followed by a few drops of concentrated HCl. The reaction mixture was stirred and refluxed continuously for 4 hours at 60 °C. The volume of the mixture was then reduced, and the solution was cooled in an ice-water bath. The precipitated crystals of acetone thiosemicarbazone were collected, washed with methanol, and dried in a desiccator over silica gel.
Reactivity Profile
Acetone thiosemicarbazone may form toxic gases with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. May form flammable gases with alkali metals. Explosive combination may occur with strong oxidizing agents, metal salts, peroxides, and sulfides. Emits toxic fumes of oxides of sulfur and nitrogen when heated to decomposition [Sax, 9th ed., 1996, p. 3165].
Health Hazard
High oral toxicity.
Fire Hazard
When heated to decomposition, Acetone thiosemicarbazone emits very toxic fumes of nitrogen oxides and sulfur oxides. Avoid decomposing heat.
Potential Exposure
Acetone thiosemicarbazone is used as an intermediate in the manufacture of pharmaceuticals and pesticides. May be used as an agricultural chemical.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides
Waste Disposal
It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.
References
[1] KPOMAH B, EGBOH S, AGBAIRE P O, et al. Metal Complexes of Acetone Thiosemicarbazone: Synthesis, Spectral Characterization and Pharmacological Studies[C]. 2016: 0. DOI:10.18576/JPAC/020203.
[2] PRIYA P. NETALKAR Vidyanand K R Sandeep P Netalkar. Transition metal complexes of thiosemicarbazone: Synthesis, structures and invitro antimicrobial studies[J]. Polyhedron, 2015, 100: Pages 215-222. DOI:10.1016/j.poly.2015.07.075.
Acetone thiosemicarbazone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29830 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Tangshan Moneide Trading Co., Ltd. | +86-315-8309571 +8615633399667 | sales@moneidechem.com | China | 574 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15083 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 | info@fortunachem.com | China | 5995 | 58 |
View Lastest Price from Acetone thiosemicarbazone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-27 | Acetone thiosemicarbazone
1752-30-3
|
US $0.00 / Kg/Drum | 1KG | 98%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-12-29 | Acetone thiosemicarbazone
1752-30-3
|
US $0.00 / KG | 1KG | 99% | According to customer requirements | Changzhou waston chemical technology Co.,Ltd | |
 |
2025-05-23 | Acetone thiosemicarbazone
1752-30-3
|
US $50.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co Ltd |
-
- Acetone thiosemicarbazone
1752-30-3
- US $0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Acetone thiosemicarbazone
1752-30-3
- US $0.00 / KG
- 99%
- Changzhou waston chemical technology Co.,Ltd
-
- Acetone thiosemicarbazone
1752-30-3
- US $50.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co Ltd
