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2-(3-(methoxycarbonyl)phenyl)acetic acid

CAS No.
52787-19-6
Chemical Name:
2-(3-(methoxycarbonyl)phenyl)acetic acid
Synonyms
[3-(Methoxycarbonyl)phenyl]acetic acid;Benzeneacetic acid, 3-(methoxycarbonyl)-;2-(3-(methoxycarbonyl)phenyl)acetic acid
CBNumber:
CB72745443
Molecular Formula:
C10H10O4
Molecular Weight:
194.18
MDL Number:
MFCD18459189
MOL File:
52787-19-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:41
Product description Number Pack Size Price
2-(3-(Methoxycarbonyl)phenyl)aceticAcid M342608 10mg $90
2-(3-(Methoxycarbonyl)phenyl)aceticacid ≥97.0% CS-0059794 50mg $70
2-(3-(Methoxycarbonyl)phenyl)aceticacid ≥97.0% CS-0059794 100mg $105
2-(3-(Methoxycarbonyl)phenyl)aceticacid ≥97.0% CS-0059794 250mg $145
2-[3-(Methoxycarbonyl)phenyl]aceticacid J97811 250mg $154

2-(3-(methoxycarbonyl)phenyl)acetic acid Properties

Melting point 83-84 °C
Boiling point 350.8±25.0 °C(Predicted)
Density 1.254±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 4.17±0.10(Predicted)
Appearance White to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2-(3-(methoxycarbonyl)phenyl)acetic acid price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M342608 2-(3-(Methoxycarbonyl)phenyl)aceticAcid 52787-19-6 10mg $90 2021-12-16 Buy
ChemScene CS-0059794 2-(3-(Methoxycarbonyl)phenyl)aceticacid ≥97.0% 52787-19-6 50mg $70 2021-12-16 Buy
ChemScene CS-0059794 2-(3-(Methoxycarbonyl)phenyl)aceticacid ≥97.0% 52787-19-6 100mg $105 2021-12-16 Buy
ChemScene CS-0059794 2-(3-(Methoxycarbonyl)phenyl)aceticacid ≥97.0% 52787-19-6 250mg $145 2021-12-16 Buy
AK Scientific J97811 2-[3-(Methoxycarbonyl)phenyl]aceticacid 52787-19-6 250mg $154 2021-12-16 Buy
Product number Packaging Price Buy
M342608 10mg $90 Buy
CS-0059794 50mg $70 Buy
CS-0059794 100mg $105 Buy
CS-0059794 250mg $145 Buy
J97811 250mg $154 Buy

2-(3-(methoxycarbonyl)phenyl)acetic acid Chemical Properties,Uses,Production

Synthesis

methyl 3-(2-methoxy-2-oxoethyl)benzoate

52787-20-9

2-(3-(methoxycarbonyl)phenyl)acetic acid

52787-19-6

Methyl 3-(methoxycarbonyl)benzoate 76 (500 mg, 2.40 mmol) was used as a raw material and dissolved in methanol (10 mL). To this solution was added a solution of K2CO3 (700 mg, 5.07 mmol) in water (10 mL) and the reaction was stirred overnight at room temperature. Upon completion of the reaction, the reaction mixture was concentrated and dissolved in water (20 mL). Subsequently, the unreacted diester 76 was extracted with water and EtOAc, and the aqueous phase was acidified with 1N HCl and then extracted with EtOAc (30 mL x 2). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated in vacuum. The crude product was purified by silica gel column chromatography (eluent: hexane/EtOAc, 5:1) to afford the target product 2-(3-(methoxycarbonyl)phenyl)acetic acid 77 (508 mg, 90% yield). The product was detected by TLC (Rf = 0.36), 1H NMR (400 MHz, methanol-d4) δ 7.97 (d, J = 1.7 Hz, 1H), 7.91 (dt, J = 7.8,1.4 Hz, 1H), 7.57-7.49 (m, 1H), 7.43 (t, J = 7.6 Hz, 1H), 3.91 (s, 3H), and 3.67 (s, 2H); mass spectral analysis showed [M + H]+ = 195.14 (APCI+).

References

[1] Patent: WO2013/52110, 2013, A1. Location in patent: Page/Page column 63; 65
[2] Journal of the Indian Chemical Society, 1987, vol. 64, # 1, p. 34 - 37
[3] Chimica Therapeutica, 1973, vol. 8, # 4, p. 487 - 494

52787-20-9
52787-19-6
Synthesis of 2-(3-(methoxycarbonyl)phenyl)acetic acid from methyl 3-(2-methoxy-2-oxoethyl)benzoate

2-(3-(methoxycarbonyl)phenyl)acetic acid Suppliers

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Shanghai Daken Advanced Materials Co.,Ltd
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View Lastest Price from 2-(3-(methoxycarbonyl)phenyl)acetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(3-(methoxycarbonyl)phenyl)acetic acid pictures 2020-01-09 2-(3-(methoxycarbonyl)phenyl)acetic acid
52787-19-6
US $1.00 / g 1g 99% 200kg Career Henan Chemical Co

2-(3-(methoxycarbonyl)phenyl)acetic acid Spectrum

2-(3-(methoxycarbonyl)phenyl)acetic acid Benzeneacetic acid, 3-(methoxycarbonyl)- [3-(Methoxycarbonyl)phenyl]acetic acid 52787-19-6