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4-Cyanobenzyl bromide

4-Cyanobenzyl bromide structure

CAS No.: 17201-43-3

Chemical Name:: 4-Cyanobenzyl bromide

Synonyms: 4-(BROMOMETHYL)BENZONITRILE;Para Cyano Benzyl Bromide;A-BROMO-P-TOLUNITRILE;4CNBB;NSC 95792;AKOS BC-3028;4-Cyanobenzyl;AKOS BBS-00003970;4-Cyanobezyl Bromide;4-Cynobenzyl bromide

CBNumber:: CB7279647

Molecular Formula:: C8H6BrN

Molecular Weight:: 196.04

MDL Number:: MFCD00001829

MOL File:: 17201-43-3.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
4-(Bromomethyl)benzonitrile 99%	144061	1g	$37.5
4-(Bromomethyl)benzonitrile 99%	144061	10g	$120
4-Cyanobenzyl Bromide >98.0%(GC)(T)	C1398	25g	$103
4-Cyanobenzyl Bromide >98.0%(GC)(T)	C1398	250g	$465
4-(Bromomethyl)benzonitrile 99%	144061	50g	$350
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4-Cyanobenzyl bromide Properties

Melting point	115-117 °C(lit.)
Boiling point	143 °C / 12mmHg
Density	1.5466 (rough estimate)
refractive index	1.6550 (estimate)
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Liquid
color	Clear colorless to yellow
Water Solubility	Soluble in chloroform and methanol. Insoluble in water.
BRN	636717
InChI	InChI=1S/C8H6BrN/c9-5-7-1-3-8(6-10)4-2-7/h1-4H,5H2
InChIKey	UMLFTCYAQPPZER-UHFFFAOYSA-N
SMILES	C(#N)C1=CC=C(CBr)C=C1
CAS DataBase Reference	17201-43-3(CAS DataBase Reference)
FDA UNII	RV332B84ZG
NIST Chemistry Reference	«ALPHA»-bromo-p-tolunitrile(17201-43-3)
EPA Substance Registry System	Benzonitrile, 4-(bromomethyl)- (17201-43-3)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS08

Signal word

Danger

Hazard statements

H314-H334

Precautionary statements

P260-P280-P284-P303+P361+P353-P304+P340+P310-P305+P351+P338

Hazard Codes

Risk Statements

34-42/43

Safety Statements

22-26-36/37/39-45-28A

RIDADR

UN 3261 8/PG 2

WGK Germany

10-19-21

Hazard Note

Corrosive

TSCA

Yes

HazardClass

PackingGroup

HS Code

29269090

Limited Quantities

1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	0
3		0

4-Cyanobenzyl bromide price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	144061	4-(Bromomethyl)benzonitrile 99%	17201-43-3	1g	$37.5	2025-07-31	Buy
Sigma-Aldrich	144061	4-(Bromomethyl)benzonitrile 99%	17201-43-3	10g	$120	2025-07-31	Buy
TCI Chemical	C1398	4-Cyanobenzyl Bromide >98.0%(GC)(T)	17201-43-3	25g	$103	2025-07-31	Buy
TCI Chemical	C1398	4-Cyanobenzyl Bromide >98.0%(GC)(T)	17201-43-3	250g	$465	2025-07-31	Buy
Sigma-Aldrich	144061	4-(Bromomethyl)benzonitrile 99%	17201-43-3	50g	$350	2025-07-31	Buy

Product number	Packaging	Price	Buy
144061	1g	$37.5	Buy
144061	10g	$120	Buy
C1398	25g	$103	Buy
C1398	250g	$465	Buy
144061	50g	$350	Buy

4-Cyanobenzyl bromide Chemical Properties,Uses,Production

Uses

4-Cyanobenzyl bromide is an important intermediate for pharmaceutical production. It can be used for the synthesis of a series of piperidine-linked aromatic diimidazolines, which have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii (PCP) drug, Pentamidine.

Chemical Properties

4-Cyanobenzyl bromide (C8H6BrN, CAS registry No. 17201-43-3) is a white solid. Its melting point is 113-117°C, and flash point is 125.1°C. It is insoluble in water at 20°C. It is stable under normal temperatures and pressures. It should be stored at 0-5°C.

Chemical Properties

white to light yellow crystal powde

Uses

A benzyl halide as postemergence herbicides.

Uses

4-(Bromomethyl)benzonitrile is used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile. It is also useful in the preparation of 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile by reaction with 2H-tetrazole in the presence of potassium hydroxide.

Uses

4-(Bromomethyl)benzonitrile may be used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile.

General Description

4-(Bromomethyl)benzonitrile reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile.

Synthesis

874-89-5

17201-43-3

GENERAL METHOD: Hydroxymethyl (1 mmol) and potassium bromide (1.5 mmol, 0.18 g) were dissolved in ethanol (5 mL) and phosphorus pentoxide (1.5 mmol, 0.23 g) was added. The reaction mixture was stirred at room temperature until the reaction was complete (monitored by TLC or GC). After completion of the reaction, the mixture was filtered and the residue was washed with ethyl acetate (3 x 8 mL). The organic layers were combined, washed with water (10 mL) and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give the crude 4-cyanobenzyl bromide product. If further purification is required, column chromatography can be used.

References

[1] Tetrahedron Letters, 2016, vol. 57, # 2, p. 168 - 171
[2] Organic Letters, 2015, vol. 17, # 15, p. 3810 - 3813
[3] Advanced Synthesis and Catalysis, 2016, vol. 358, # 11, p. 1731 - 1735
[4] Patent: US6384080, 2002, B1

4-Cyanobenzyl bromide Preparation Products And Raw materials

Raw materials

p-Tolunitrile 4-(HYDROXYMETHYL)BENZONITRILE Benzoyl peroxide Phosphorus pentoxide Acetonitrile

Potassium bromide

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Preparation Products

TERT-BUTYL 4-(4-FORMYLBENZYL)PIPERAZINE-1-CARBOXYLATE 4-Cyanobenzoic acid Letrozole 4-(4-CYANOBENZYL)-1,2,4-TRIAZOLE (4-CYANOBENZYL)PHOSPHONIC ACID DIETHYL ESTER

4-CYANOPHENYLACETONITRILE 97 Ethyl 4-(bromomethyl)benzoate TERT-BUTYL 4-(BROMOMETHYL)BENZYLCARBAMATE (4-AMINOMETHYL-PHENYL)-METHANOL Bromoethane

4-[1-Cyano-2-(4-cyanophenyl)ethyl]benzonitrile Thioacetic acid S-(4-cyano-benzyl) ester 3-MORPHOLIN-4-YLMETHYL-BENZYLAMINE

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4-Cyanobenzyl bromide Suppliers

Global( 498)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan BJM Pharm Inc	027-52341919 13545198479	sales03@benjaminpharmchem.com	China	585	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29734	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Speranza Chemical Co., Ltd.	+86-86-075521030354 +8618688942810	sophieliu@speranzachem.com	China	925	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	info@tnjchem.com	China	2988	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Win-Win Chemical CO., Limited	0086-577-64498589	sales@win-winchemical.com	CHINA	998	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58

Supplier	Advantage
Wuhan BJM Pharm Inc	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Speranza Chemical Co., Ltd.	55
Hefei TNJ Chemical Industry Co.,Ltd.	55
career henan chemical co	58
Win-Win Chemical CO., Limited	58
Changzhou Ansciep Chemical Co., Ltd.	58

Synthesis and Pharmaceutical Applications of 4-Cyanobenzyl Bromide
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View Lastest Price from 4-Cyanobenzyl bromide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-16	4-Cyanobenzyl bromide 17201-43-3	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2021-10-21	4-Cyanobenzyl bromide 17201-43-3	US $10.00 / KG	1KG	99%	20 tons	Hebei Zhanyao Biotechnology Co. Ltd
2019-07-06	4-Cyanobenzyl bromide 17201-43-3	US $1.00 / KG	1KG	99%	1000KG	Career Henan Chemical Co

4-Cyanobenzyl bromide
17201-43-3
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

4-Cyanobenzyl bromide
17201-43-3
US $10.00 / KG
99%
Hebei Zhanyao Biotechnology Co. Ltd

4-Cyanobenzyl bromide
17201-43-3
US $1.00 / KG
99%
Career Henan Chemical Co

4-Cyanobenzyl bromide Spectrum

4-Cyanobenzyl bromide(17201-43-3)MS 4-Cyanobenzyl bromide(17201-43-3)¹HNMR 4-Cyanobenzyl bromide(17201-43-3)¹³CNMR 4-Cyanobenzyl bromide(17201-43-3)IR1 4-Cyanobenzyl bromide(17201-43-3)IR2 4-Cyanobenzyl bromide(17201-43-3)Raman

17201-43-3(4-Cyanobenzyl bromide)Related Search:

Methyl 4-cyanobenzoate 4-Cyanobenzoyl chloride Ethidium bromide 4-Cyanophenol Sodium bromate

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Methylene dithiocyanate Diethylstilbestrol Benzyl bromide Allyl bromide Cyanoacetic acid

α-Lipoic Acid 2-Fluoro-4-cyanobenzyl bromide Bromine

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4-(bromomethyl)-benzonitril 4-(BROMOMETHYL)BENZONITRILE 4CNBB 4-CYANOBENZYL BROMIDE Benzonitrile, 4-(bromomethyl)- Benzonitrile, p-(bromomethyl)- p-(Bromomethyl)benzonitrile p-Tolunitrile, alpha-bromo- p-Toluonitrile, alpha-bromo- P-CYANOBENZYL BROMIDE A-BROMO-P-TOLUNITRILE AKOS BBS-00003970 AKOS BC-3028 4-Bromomethyl benzonitrie CYANOBENZYLBROMIDE(P-) BROMO(ALPHA-)-P-TOLUNITRILE 4-Cyanobenzyl broMide SynonyMs alpha-BroMo-p-tolunitrile ALPHA-BROMO-P-TOLUNITRILE ALPHA-BROMO-P-TOLUONITRILE 4-(Bromomethyl)benzonitrile/alpha-Bromo-p-tolunitrile 4-Cyanobenzylbromide/4-CNBB 4-Cyanobenzyl à-bromo-p-tolunitrile a-Bromo-p-toluonitrile. 4-Cyanobenzyl bromide 98% 4-Bromomethylbenzonitribe alpha-bromo-para-tolunitrile a-Bromo-p-tolunitrile, (4-Cyanobenzyl bromide) NSC 95792 α-Bromo-p-tolylnitrile α-Bromo-p-tolunitrile, 4-Cyanobenzyl bromide 4-Cyanophenyl)methyl bromide a-Bromo-p-toluenecarbonitrile 4-Cyanobenzyl bromide ,98% α-Bromo-4-cyanotoluene alpha-Bromo-p-tolunitrile,98% 4-(bromomethy)benzonitrile 4-Cyano benzyl broMide (P-Cyano benzyl broMide) 4-Cyanobenzyl bromide, alpha-Bromo-p-tolunitrile 4-(broMoMrthyl)-benaonitril a-Bromo-p-tolylnitrile 4-bromomethyl benzoic nitrile p-Cyanobenzyl Bromide 4-(Bromomethyl)Benzonitrile 4-Cyanobenzyl bromide 4-bromomethyl benzonitrile 4-Cyanobenzyl Bromide > 4-Cyanobezyl Bromide 4-(BROMOMETHYL)BENZONITRILE 1 4-Cyanobenzyl bromide ISO 9001：2015 REACH Para Cyano Benzyl Bromide 4-Cyanobenzyl bromide 17201-43-3 4-Bromomethyl Benzonitrile/4-Cyano Benzyl Bromide 13C7,15N]-4-(Bromomethyl)benzonitrile 4-Cynobenzyl bromide 4-(Bromomethyl)benzonitrile, 98% 17201-43-3 17301-43-3 17201-43-4 17201-43-4

4-Cyanobenzyl bromide

4-Cyanobenzyl bromide Properties

SAFETY

Risk and Safety Statements

4-Cyanobenzyl bromide price More Price(38)

4-Cyanobenzyl bromide Chemical Properties,Uses,Production

Uses

Chemical Properties

Chemical Properties

Uses

Uses

Uses

General Description

Synthesis

References

4-Cyanobenzyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

4-Cyanobenzyl bromide Suppliers

Related articles

View Lastest Price from 4-Cyanobenzyl bromide manufacturers

4-Cyanobenzyl bromide Spectrum

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