Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2,5-Dibromopyridine

2,5-Dibromopyridine

2,5-Dibromopyridine Structure
2,5-Dibromopyridine structure
CAS No.
624-28-2
Chemical Name:
2,5-Dibromopyridine
Synonyms
Dibromopyridine;NSC 76597;5-DibroMop;2,5-DBr-Py;5-DibroMopyridine;2,5-Dibrompyridin;2,5-dibromopyridin;2,5 dibromopyrdine;3,6-DibroMopyridine;2,5-DIBROMOPYRIDINE
CBNumber:
CB7283491
Molecular Formula:
C5H3Br2N
Molecular Weight:
236.89
MDL Number:
MFCD00006221
MOL File:
624-28-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-23 17:18:35
Request For Quotation

2,5-Dibromopyridine Properties

Melting point 92-95 °C (lit.)
Boiling point 235 °C / 772mmHg
Density 2.0383 (rough estimate)
refractive index 1.5800 (estimate)
Flash point 62℃
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka -1.57±0.10(Predicted)
form Crystalline Powder
color Almost white or light beige to brown
Water Solubility insoluble
BRN 109099
InChI InChI=1S/C5H3Br2N/c6-4-1-2-5(7)8-3-4/h1-3H
InChIKey ZHXUWDPHUQHFOV-UHFFFAOYSA-N
SMILES C1(Br)=NC=C(Br)C=C1
CAS DataBase Reference 624-28-2(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H335-H302+H312+H332-H315-H319
Precautionary statements  P280a-P304+P340-P305+P351+P338-P405-P501a-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-37/39-36/37/39-36
RIDADR  UN2811
WGK Germany  3
HazardClass  IRRITANT
HS Code  29333999
Storage Class 11 - Combustible Solids
REACH Registrations Inactive
NFPA 704
0
2 0

2,5-Dibromopyridine price More Price(90)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D43107 2,5-Dibromopyridine 98% 624-28-2 10g $106 2026-04-30 Buy
TCI Chemical D1217 2,5-Dibromopyridine >99.0%(GC) 624-28-2 5g $25 2026-04-30 Buy
TCI Chemical D1217 2,5-Dibromopyridine >99.0%(GC) 624-28-2 25g $68 2026-04-30 Buy
Usbiological D3483 2,5-Dibromopyridine 20g $312 2026-06-03 Buy
TRC TRC-D425472-10G 2,5-Dibromopyridine 624-28-2 10g $72 2026-06-03 Buy
Product number Packaging Price Buy
D43107 10g $106 Buy
D1217 5g $25 Buy
D1217 25g $68 Buy
D3483 20g $312 Buy
TRC-D425472-10G 10g $72 Buy

2,5-Dibromopyridine Chemical Properties, Uses, Production

Description

Pyridine and its derivatives are distributed widely by nature. Many plant constituents are as contain pyridine ring compounds in the structure of alkaloids, etc.; they are the bases producing many vital compounds and are indispensable raw materials during medicine, agricultural chemicals, dyestuff, tension-active agents, rubber ingredients, fodder additives, foodstuff additives, tackiness agents, etc. are produced.2,5-dibromo pyridine is an important intermediate of organic synthesis and is mainly used in medicine intermediate, organic synthesis, and organic solvent, can also be applicable to aspects such as DYE PRODUCTION, pesticide production and spices. Selective monolithiation of 2,5-dibromopyridine at either the 2-position or the 5-position is reported. Solvent and concentration strongly influence the selectivity. Coordinating solvents and higher concentration favour the 5-position, while non-coordinating solvents and lower concentration favour the 2-position[1].

Chemical Properties

2,5-Dibromopyridine is an off-white crystalline solid. It is insoluble in water but soluble in strong polar organic solvents. It exhibits strong alkalinity.

Uses

2,5-Dibromopyridine (cas# 624-28-2) is a compound useful in organic synthesis.

Preparation

To synthesize 2,5-dibromopyridine, follow these steps:
Add 2-amino-5-bromopyridine (13.0 kg) into a water-cooled solution at 10 °C.
Slowly add 47% aqueous hydrogen bromide (37 L) to the mixture.
Introduce liquid bromine (11 L) into the mixture.
Maintain the reaction temperature below 10 °C.
Prepare a solution of NaNO2 (16.1 kg) and H2O (19 L) and add it dropwise to the mixture while keeping the temperature between 0-5 °C.
Stir the reaction mixture for 30 minutes.
Treat the mixture with a solution of NaOH (28.0 kg) in water (30 L) at a controlled rate below 20-25 °C.
Extract the reaction mixture with diethyl ether (3 × 40 L).
Dry the organic layer with anhydrous Na2SO4.
Remove the desiccant by filtration.
Evaporate the resulting filtrate under reduced pressure to dryness.
Suspend the residue in heptane (10 L).
Collect the target product molecule, 2,5-dibromopyridine, by filtration.
Synthesis method of 2,5-dibromopyridine

Application

2,5-Dibromopyridine is the important intermediate of organic synthesis, is mainly used in medicine intermediate, organic synthesis, organic solvent, also can be applicable to the aspects such as DYE PRODUCTION, pesticide producing and spices.

References

[1] Xin Wang. “Selective monolithiation of 2,5-dibromopyridine with butyllithium.” Tetrahedron Letters 41 1 (2000): 4335–4338.

2,5-Dibromopyridine synthesis

13466-38-1
624-28-2
Synthesis of 2,5-Dibromopyridine from 2-Hydroxy-5-bromopyridine

2,5-Dibromopyridine Preparation Products And Raw materials

Raw materials

2-Amino-5-bromopyridine Hydrogen bromide Sodium nitrite 2,3,6-Tribromopyridine 2,3,5-Tribromopyridine
2-Hydroxy-5-bromopyridine 1-Methyl-2-pyridone

1of2

Preparation Products

2-Bromo-5-iodopyridine 5-Bromo-2-pyridinecarboxylic Acid 5-Bromopyridine-2-carbonyl chloride 6-Methoxynicotinaldehyde 2-(5-Bromo-2-pyridylazo)-5-(diethylamino)phenol
2-Bromopyridine-5-boronic acid 5-(Trifluoromethyl)pyridine-2-carboxylic acid 5-Bromo-2-(pyrrolidin-1-yl)pyridine 6-(1-Pyrrolidinyl)nicotinaldehyde 5-Bromo-3-pyridinecarboxaldehyde
2-Trifluoromethyl-5-bromopyridine 5-Bromo-2-iodopyridine Torezolid 2,5-Bis(trifluoromethyl)pyridine

1of3

2,5-Dibromopyridine Suppliers

Global Suppliers ( 863)
Supplier Tel Email Country ProdList Advantage
Jiangxi Estik Technology Development Co., Ltd 02158999881 19892935632 business@xpertick.cn China 50 58
Changzhou Yuxiang Chemical Co., Ltd 13809076511 344679571@qq.com China 311 58
Nanjing Chao Yi Biotechnology Co., Ltd. 025-52614296 17761738099; chenxin@njcychem.com China 53 55
Shanghai Taijilin Industrial Co., Ltd. 02150630626 17717886015 kate@tajilin.com China 1342 58
Changzhow Moisten International Trading Co., Ltd. 13606112397 tang13606112397@163.com China 191 58
Beijing Dongxing Science and Technology Co.,Ltd 15801121354; 15801121354 dx_chem@sina.com China 23 58
XPERTICK (SHANDONG) BIO-PHARMACEUTICAL CO., LTD 21-58999881 15623240527 emily@xtick.cn China 61 58
Oscar (Liaoning) Technology Co., Ltd 16642274934 16642274934 1589053741@qq.com China 244 58
Shandong Taiqinoviv Pharmaceutical Technology Co., Ltd. 13188900221 18860593218 306089116@qq.com China 16 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Supplier Advantage
Jiangxi Estik Technology Development Co., Ltd 58
Changzhou Yuxiang Chemical Co., Ltd 58
Nanjing Chao Yi Biotechnology Co., Ltd. 55
Shanghai Taijilin Industrial Co., Ltd. 58
Changzhow Moisten International Trading Co., Ltd. 58
Beijing Dongxing Science and Technology Co.,Ltd 58
XPERTICK (SHANDONG) BIO-PHARMACEUTICAL CO., LTD 58
Oscar (Liaoning) Technology Co., Ltd 58
Shandong Taiqinoviv Pharmaceutical Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76

Related articles

View Latest Price from 2,5-Dibromopyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,5-Di Bromo Pyridine pictures 2026-10-08 2,5-Di Bromo Pyridine
624-28-2
 $100.00 1KG 99% 1000 KG HANGZHOU DINGYAN CHEM CO.,LTD
2,5-Dibromopyridine pictures 2026-10-02 2,5-Dibromopyridine
624-28-2
 $136.00 1kg 0.99 100kg Shanghai UCHEM Inc.
2,5-Dibromopyridine pictures 2026-09-02 2,5-Dibromopyridine
624-28-2
 $5.00 1KG 98% Henan Fengda Chemical Co., Ltd

2,5-Dibromopyridine Spectrum

2,5-Dibromopyridine(624-28-2)MS2,5-Dibromopyridine(624-28-2)1HNMR2,5-Dibromopyridine(624-28-2)IR12,5-Dibromopyridine(624-28-2)IR22,5-Dibromopyridine(624-28-2)Raman

624-28-2 (2,5-Dibromopyridine) Related Search:

3,5-DIBROMOPYRIDINE 1,3-Bis(bromomethyl)benzene 2,2-Bis(bromomethyl)propane-1,3-diol DBDCB 1,3-Dibromo-5,5-dimethylhydantoin
2,3-Dibromosuccinic acid 2-Chloro-3-cyanopyridine 1,2-Dibromopropane 2,4-Dibromopentane 1,2-Dibromoethylene
PeraMpanel PeraMpanel 5'-(2-cyanophenyl)-6'-oxo-1'-phenyl-1',6'-dihydro-[2,3'-bipyridine] 1-oxide 4-(6'-oxo-1'-phenyl-1',6'-dihydro-[2,3'-bipyridin]-5'-yl)benzonitrile 2-bromo-3-(1,3,2-dioxaborinan-2-yl)benzonitrile
6'-Methoxy-2,3'-bipyridine 2-Phenyl-1,3,2-dioxaborinane 2-Cyanophenylboronic acid

1of4

2,5-DIBROMOPYRIDINE PYRIDINE, 2,5-DIBROMO- 2,5-Dibromopyridine, 97+% 2,5-dibromopyridin 2,5-DIBROMOPYRIDINE 2,5-DIBROMOPYRIDINE 2,5-Dibromo pyridine ,98% 2,5-DibroMopyridine, 97% 10GR 3,6-DibroMopyridine NSC 76597 5-DibroMopyridine 2, 5-2 broMide pyridine 2,5 Di bromo pyridne 2,5-Dibromopyridine > Perampanel Impurity 9 2,5-Dibromopyridine ISO 9001：2015 REACH 2,5-Dibrompyridin 2,5 dibromopyrdine Hot Sale?2, 5-Dibromopyridine CAS?624-28-2?with Best Price Pyronoprene Impurity 17 Nicotinic Acid Impurity 13 Dibromopyridine 5-DibroMop 2,5-DBr-Py Pyridine-2,5-dibromide 624-28-2 324-28-2 1450-73-9 Building Blocks Pyridines Halogenated Heterocycles Heterocyclic Building Blocks Bromopyridines Halopyridines alkyl bromide Building Blocks C5 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Brominated heterocyclic series Aromatics Bases & Related Reagents Nucleotides Aromatics Compounds Bromopyridines Halopyridines Pyridine series C5Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Nitrogen cyclic compounds blocks Bromides Pyridines pyridine derivative Pyridines, Pyrimidines, Purines and Pteredines Halides Pyridine