1-Chloro-3-iodobenzene
- CAS No.
- 625-99-0
- Chemical Name:
- 1-Chloro-3-iodobenzene
- Synonyms
- 3-CHLOROIODOBENZENE;oroiodobenzene;3-chloroiodine;Chloriodobenzene;3-Iodochlorobenzene;M-IODOCHLOROBENZENE;M-CHLOROIODOBENZENE;m-Chlorophenyl iodide;1-CHLORO-3-IODOBENZENE;3-Chloro-1-iodobenzene
- CBNumber:
- CB7286689
- Molecular Formula:
- C6H4ClI
- Molecular Weight:
- 238.45
- MDL Number:
- MFCD00001046
- MOL File:
- 625-99-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Chloroiodobenzene 98% | 242578 | 5g | $47.1 |
| 3-Chloroiodobenzene 98% | 242578 | 25g | $135 |
| 1-Chloro-3-iodobenzene (stabilized with Copper chip) | C0190 | 5G | $17 |
| 1-Chloro-3-iodobenzene (stabilized with Copper chip) | C0190 | 25G | $55 |
| 1-Chloro-3-iodobenzene, min. 99% min.99% | 06-0081 | 25g | $52 |
| More product size | |||
| Melting point | 95-96 °C |
|---|---|
| Boiling point | 103-104 °C15 mm Hg(lit.) |
| Density | 1.926 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 215 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Liquid |
| Specific Gravity | 1.926 |
| color | Clear light yellow |
| Water Solubility | Soluble in water 67.2 mg/L. |
| Sensitive | Light Sensitive |
| BRN | 1904539 |
| InChI | 1S/C6H4ClI/c7-5-2-1-3-6(8)4-5/h1-4H |
| InChIKey | JMLWXCJXOYDXRN-UHFFFAOYSA-N |
| SMILES | Clc1cccc(I)c1 |
| CAS DataBase Reference | 625-99-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-chloro-3-iodo-(625-99-0) |
| EPA Substance Registry System | Benzene, 1-chloro-3-iodo- (625-99-0) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29039990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
1-Chloro-3-iodobenzene price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 242578 | 3-Chloroiodobenzene 98% | 625-99-0 | 5g | $47.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 242578 | 3-Chloroiodobenzene 98% | 625-99-0 | 25g | $135 | 2023-06-20 | Buy |
| TCI Chemical | C0190 | 1-Chloro-3-iodobenzene (stabilized with Copper chip) | 625-99-0 | 5G | $17 | 2026-04-30 | Buy |
| TCI Chemical | C0190 | 1-Chloro-3-iodobenzene (stabilized with Copper chip) | 625-99-0 | 25G | $55 | 2026-04-30 | Buy |
| Strem Chemicals | 06-0081 | 1-Chloro-3-iodobenzene, min. 99% min.99% | 625-99-0 | 25g | $52 | 2026-04-30 | Buy |
1-Chloro-3-iodobenzene Chemical Properties,Uses,Production
Chemical Properties
Clear light yellow liquid
Uses
suzuki reaction
Uses
1-Chloro-3-iodobenzene is used as a pharmaceutical intermediate.
Synthesis Reference(s)
Synthetic Communications, 11, p. 639, 1981 DOI: 10.1080/00397918108063637
General Description
The multiple-quantum proton NMR spectra of 3-chloroiodobenzene was studied.
Synthesis
63503-60-6
625-99-0
General procedure for the synthesis of m-chloroiodobenzene from 3-chlorophenylboronic acid: a mixture of arylboronic acid (0.55 mmol), KF (96 mg, 1.65 mmol) and I2 (127 mg, 0.50 mmol) in 1,4-dioxane (5 mL) was stirred and reacted for 1 hr at 80 °C. After completion of the reaction, the mixture was filtered through a silica gel column and eluted with ether (10 mL). Subsequently, the solvent was removed by rotary evaporator. For further purification, the target product, m-chloroiodobenzene, was isolated by silica gel column chromatography using petroleum ether/ether (98:2) as eluent.
References
[1] Chemistry - A European Journal, 2011, vol. 17, # 20, p. 5652 - 5660
[2] Tetrahedron Letters, 2015, vol. 56, # 9, p. 1122 - 1123
[3] Synlett, 1998, # 2, p. 141 - 142
[4] Synlett, 2014, vol. 25, # 7, p. 995 - 1000
1-Chloro-3-iodobenzene Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 967 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
View Lastest Price from 1-Chloro-3-iodobenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-09-25 | 1-Chloro-3-iodobenzene
625-99-0
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
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2025-04-15 | 1-Chloro-3-iodobenzene
625-99-0
|
$30.00 | 1kg | 99% | 5000kg/week | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
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2021-07-13 | 1-Chloro-3-iodobenzene
625-99-0
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-

- 1-Chloro-3-iodobenzene
625-99-0
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 1-Chloro-3-iodobenzene
625-99-0
- $30.00
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-

- 1-Chloro-3-iodobenzene
625-99-0
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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