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H-Ser(tBu)-OH

H-Ser(tBu)-OH structure

CAS No.: 18822-58-7

Chemical Name:: H-Ser(tBu)-OH

Synonyms: Ser(tBu);L-Ser(tBu)-OH;(S)-2-AMino-3-(tert-butoxy)propanoic acid;H-L-Ser(tBu)-OH;O-T-BUTYL-L-SERINE;O-TERT-BUTYL-L-SERINE;H-Ser(Tub)-OH;H-SER(BUT)-OH;H-Ser(tBu)-OH;SERINE(TBU)-OH

CBNumber:: CB7299643

Molecular Formula:: C7H15NO3

Molecular Weight:: 161.2

MDL Number:: MFCD00066088

MOL File:: 18822-58-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:54:54

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H-Ser(tBu)-OH Properties

Melting point	~220 °C (dec.)
Boiling point	266.0±30.0 °C(Predicted)
Density	1.080±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka	2.11±0.10(Predicted)
form	Powder
color	White
optical activity	Consistent with structure
Water Solubility	Soluble in water.
CAS DataBase Reference	18822-58-7(CAS DataBase Reference)
FDA UNII	BX0H592PIC

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Safety Statements

22-24/25

WGK Germany

HS Code

29225090

NFPA 704

	1
0		0

H-Ser(tBu)-OH price More Price(61)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B3917	O-tert-Butyl-L-serine >97.0%(HPLC)(T)	18822-58-7	1g	$37	2026-04-30	Buy
TCI Chemical	B3917	O-tert-Butyl-L-serine >97.0%(HPLC)(T)	18822-58-7	5g	$127	2026-04-30	Buy
Usbiological	264607	O-tert-Butyl-L-serine Asreported	18822-58-7	2g	$333	2026-06-03	Buy
Usbiological	264607	O-tert-Butyl-L-serine Asreported	18822-58-7	5g	$483	2026-06-03	Buy
Usbiological	264607	O-tert-Butyl-L-serine Asreported	18822-58-7	10g	$654	2026-06-03	Buy

Product number	Packaging	Price	Buy
B3917	1g	$37	Buy
B3917	5g	$127	Buy
264607	2g	$333	Buy
264607	5g	$483	Buy
264607	10g	$654	Buy

H-Ser(tBu)-OH Chemical Properties, Uses, Production

Chemical Properties

White powder

Uses

O-tert-Butyl-L-serine tert-butyl ester hydrochloride is a protected L-serine used in peptide synthesis, e.g. synthesis of glycopeptides and lipopeptides and preparation of amino-phospholipids. O-tert-Butyl-L-serine (Ser(TBU-OH), a serine hydroxyl protected amino acid, is used in SPPS such as the synthesis of tailed cyclic RGD peptides to prevent glutarimide formation.

H-Ser(tBu)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

FMOC-O-tert-Butyl-L-serine

H-Ser(tBu)-OH Suppliers

Global Suppliers ( 275)

Supplier	Tel	Email	Country	ProdList	Advantage
Gansu Province Baishixing Pharmaceutical Co.,Ltd	15008395229 15008395229	zhangqing@gs-bsx.com	China	50	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Sichuan Tongsheng Amino acids Co.,Ltd.	0838-2274206 17340404235	sales@biots.cn	China	300	66
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	+86-21-54098501	sales@sinch.com.cn	China	11592	64

Supplier	Advantage
Gansu Province Baishixing Pharmaceutical Co.,Ltd	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
Sichuan Tongsheng Amino acids Co.,Ltd.	66
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
GL Biochem (Shanghai) Ltd	64
Capot Chemical Co., Ltd	66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	64

View Latest Price from H-Ser(tBu)-OH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-16	H-SER(TBU)-OH 18822-58-7		1kg	98+	1T	Sichuan HongRi Pharma-Tech Co.,Ltd
2026-08-13	H-SER(TBU)-OH 18822-58-7		1G	98%	500	Shenzhen Nexcon Pharmatechs Ltd.
2019-07-06	H-SER(TBU)-OH 18822-58-7	$1.00	1KG	98%	1kg,5kg,100kg	Career Henan Chemical Co

H-SER(TBU)-OH
18822-58-7
98+
Sichuan HongRi Pharma-Tech Co.,Ltd

H-SER(TBU)-OH
18822-58-7
98%
Shenzhen Nexcon Pharmatechs Ltd.

H-SER(TBU)-OH
18822-58-7
$1.00
98%
Career Henan Chemical Co

H-Ser(tBu)-OH Spectrum

H-SER(TBU)-OH(18822-58-7)¹HNMR

18822-58-7 (H-Ser(tBu)-OH) Related Search:

H-Ser(SO3H)-OH.HCl H-Ser(tBu)-OBzl.HCl L-Serine,O-(triphenylmethyl)- L-Ser-OBzl.HCl L-Serine methyl ester hydrochloride

O-tert-Butyl-L-serine methyl ester hydrochloride H-Ser-OtBu · HCl H-Ser(Bzl)-OBzl·HCl L-Serinamide hydrochloride O-Benzyl-L-serine

H-Ser(tBu)-OtBu HCl O-Benzyl-L-serine methyl ester hydrochloride O-Acetyl-L-serine H-Ser-Ser-OH H-Ser-Ala-OH

H-Thr(tBu)-OtBu.AcOH Z-Thr(tBu)-OH dcha H-Thr(tBu)-OH

1of4

L-SERINE T-BUTYL ETHER H-SER(BUT)-OH SERINE(TBU)-OH O-tert-Butyl-L-serine≥ 99% (HPLC, Chiral purity) H-Ser(Tub)-OH O-TERT0BUTYL-L-SERINE O-t-Butyl-L-serine, (S)-2-Amino-3-t-butoxypropanoic acid (2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoicacid (2S)-2-amino-3-(tert-butoxy)propanoic acid O-tert-Butyl-L-serine > L-Serine, O-(1,1-dimethylethyl)- (2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoicaci O-tert-Butyl-L-Serine extrapure, 97% O-(1,1-Dimethylethyl)-L-serine 0-tert-butyl-L-serine (S)-2-AMino-3-(tert-butoxy)propanoic acid H-L-Ser(tBu)-OH L-Ser(tBu)-OH O-T-BUTYL-L-SERINE O-TERT-BUTYL-L-SERINE Ser(tBu) H-Ser(tBu)-OH 18822-58-7 Specialty Synthesis Peptide Synthesis Serine Carboxylic acid Amino Acid Derivatives Serine [Ser, S] Amino Acids and Derivatives Peptide Synthesis A - HPeptide Synthesis Amino Acid Derivatives Amino Acids Modified Amino Acids Serine Amino Acids