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ChemicalBook >> CAS DataBase List >>L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI)

L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI)

L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) Structure
L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) structure
CAS No.
864238-20-0
Chemical Name:
L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI)
Synonyms
MMAF intermediate 2;(S) 2- ((2R, 3R) -3-methoxy-2-methyl-3- ((S) - pyrrolidin-2-yl) propionylamino);methyl ((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanoyl)-L-phenylalaninate hydrochloride;(S)-methyl 2-((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanamido)-3-phenylpropanoate hydrochloride;L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI)
CBNumber:
CB73053909
Molecular Formula:
C19H28N2O4.ClH
Molecular Weight:
384.9
MDL Number:
MFCD28387092
MOL File:
864238-20-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:02:23
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L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) Properties

form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00GU69 L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) 99% 864238-20-0 10mg $33 2026-05-28 Buy
ACHEMBLOCK AD243077 (S)-methyl 2-((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanamido)-3-phenylpropanoate hydrochloride 95% 864238-20-0 100MG $360 2026-05-27 Buy
ACHEMBLOCK AD243077 (S)-methyl 2-((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanamido)-3-phenylpropanoate hydrochloride 95% 864238-20-0 250MG $875 2026-05-27 Buy
Chemenu CM543646 (S)-methyl 2-((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanamido)-3-phenylpropanoate hydrochloride 96% 864238-20-0 100mg $900 2026-05-26 Buy
Chemenu CM543646 (S)-methyl 2-((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanamido)-3-phenylpropanoate hydrochloride 96% 864238-20-0 250mg $1500 2026-05-26 Buy
Product number Packaging Price Buy
AA00GU69 10mg $33 Buy
AD243077 100MG $360 Buy
AD243077 250MG $875 Buy
CM543646 100mg $900 Buy
CM543646 250mg $1500 Buy

L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) Chemical Properties, Uses, Production

Uses

MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1].

References

[1] Lee JW, et al. EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma. Clin Cancer Res. 2010 May 1;16(9):2562-70. [Content Brief] DOI:10.1158/1078-0432.CCR-10-0017

L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) Suppliers

Global Suppliers ( 11)
Supplier Tel Email Country ProdList Advantage
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
Tianjin Chempharmatech Co.,Ltd. 022-66211079 13212288319 sales@chempharmatech.com China 943 55
Shanghai zhigan biotechnology co., LTD zhiqianbio@126.com China 19765 58
Dideu Industries Group Limited +8617392712697 1022@dideu.com China 29090 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2934 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
YJ Pharma 13962794339 Sales@yucarepharma.com China 294 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Protheragen-ING +86-15618352007 info@protheragen-ing.com United States 3867 58
Supplier Advantage
Haoyuan Chemexpress Co., Ltd. 61
Tianjin Chempharmatech Co.,Ltd. 55
Shanghai zhigan biotechnology co., LTD 58
Dideu Industries Group Limited 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Shanghai Tachizaki Biomedical Research Center 58
TargetMol Chemicals Inc. 58
YJ Pharma 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 58
Protheragen-ING 58

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(S)-methyl 2-((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanamido)-3-phenylpropanoate hydrochloride methyl ((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanoyl)-L-phenylalaninate hydrochloride L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) MMAF intermediate 2 (S) 2- ((2R, 3R) -3-methoxy-2-methyl-3- ((S) - pyrrolidin-2-yl) propionylamino) 864238-20-0