3-Chloro-4-formylbenzonitrile
- CAS No.
- 58588-64-0
- Chemical Name:
- 3-Chloro-4-formylbenzonitrile
- Synonyms
- 2-Chloro-4-Cyanobenzaldehyd;3-Chloro-4-formylbenzonitrile;Benzonitrile, 3-chloro-4-formyl-
- CBNumber:
- CB73064590
- Molecular Formula:
- C8H4ClNO
- Molecular Weight:
- 165.58
- MDL Number:
- MFCD11036376
- MOL File:
- 58588-64-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Chloro-4-formylbenzonitrile | C384563 | 100mg | $60 |
| 3-Chloro-4-formylbenzonitrile 98.61% | CS-0130923 | 1g | $110 |
| 3-Chloro-4-formylbenzonitrile 98.61% | CS-0130923 | 5g | $380 |
| 3-CHLORO-4-FORMYLBENZONITRILE 95.00% | HCH0361106 | 5MG | $497.01 |
| 3-chloro-4-formylbenzonitrile | 5563AQ | 5g | $555.2 |
| More product size | |||
| Melting point | 117-119 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 288.8±25.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| Appearance | Light yellow to yellow Solid |
| InChI | InChI=1S/C8H4ClNO/c9-8-3-6(4-10)1-2-7(8)5-11/h1-3,5H |
| InChIKey | UGRNLUNAHZKZTG-UHFFFAOYSA-N |
| SMILES | C(#N)C1=CC=C(C=O)C(Cl)=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| HS Code | 2926907090 |
3-Chloro-4-formylbenzonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C384563 | 3-Chloro-4-formylbenzonitrile | 58588-64-0 | 100mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-0130923 | 3-Chloro-4-formylbenzonitrile 98.61% | 58588-64-0 | 1g | $110 | 2021-12-16 | Buy |
| ChemScene | CS-0130923 | 3-Chloro-4-formylbenzonitrile 98.61% | 58588-64-0 | 5g | $380 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0361106 | 3-CHLORO-4-FORMYLBENZONITRILE 95.00% | 58588-64-0 | 5MG | $497.01 | 2021-12-16 | Buy |
| AK Scientific | 5563AQ | 3-chloro-4-formylbenzonitrile | 58588-64-0 | 5g | $555.2 | 2021-12-16 | Buy |
3-Chloro-4-formylbenzonitrile Chemical Properties,Uses,Production
Synthesis
![Benzonitrile, 3-chloro-4-[2-(dimethylamino)ethenyl]-](/CAS/20210305/GIF/1050477-54-7.gif)
1050477-54-7
58588-64-0
General procedure for the synthesis of 3-chloro-4-formylbenzonitrile using compound (CAS:1050477-54-7) as starting material: the crude product 3-chloro-4-[2-(dimethylamino)vinyl]benzonitrile was dissolved in 500 mL of THF/water (1:1) mixed solvent and 77.6 g (362.9 mmol) of sodium iodide was added. The reaction mixture was stirred at room temperature for 18 h, followed by filtration to remove the precipitate precipitated. The filtrate was mixed with saturated sodium bicarbonate solution and extracted three times with ethyl acetate. The organic phases were combined, dried with sodium sulfate and the solvent was subsequently removed by rotary evaporator. The crude product was purified by silica gel column chromatography with cyclohexane/ethyl acetate (3:7) as mobile phase. 3.0 g of 3-chloro-4-formylbenzonitrile was finally obtained in 15% yield of the theoretical value.
References
[1] Patent: US2010/305052, 2010, A1. Location in patent: Page/Page column 24
[2] Patent: KR101614164, 2016, B1. Location in patent: Paragraph 0363-0365; 0367
3-Chloro-4-formylbenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3986 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30228 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14343 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5661 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
