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2-Chloro-5-nitropyrimidine

2-Chloro-5-nitropyrimidine structure

CAS No.: 10320-42-0

Chemical Name:: 2-Chloro-5-nitropyrimidine

Synonyms: 2-CHLORO-5-NITRO-;CHLORO(2-)-5-NITROPYRIDINE;2-CHLORO-5-NITROPYRIMIDINE;PYRIDINE, 2-CHLORO-5-NITRO-;2-Chloro-5-nitro-1,3-diazine;PYRIMIDINE, 2-CHLORO-5-NITRO-;2-Chloro-5-nitropyrimidine 98%;2-Chloro-5-nitropyrimidine >2-Chloro-5-nitropyrimidine ,98%;2-Chloro-5-nitropyrimidine ISO 9001：2015 REACH

CBNumber:: CB7307005

Molecular Formula:: C4H2ClN3O2

Molecular Weight:: 159.53

MDL Number:: MFCD04117995

MOL File:: 10320-42-0.mol

MSDS File:: SDS

Last updated:2026-01-13 15:44:13

Product description	Number	Pack Size	Price
2-Chloro-5-nitropyrimidine 97%	720348	250mg	$101
2-Chloro-5-nitropyrimidine 97%	720348	1g	$209
2-Chloro-5-nitropyrimidine >98.0%(GC)	C2507	1g	$65
2-Chloro-5-nitropyrimidine >98.0%(GC)	C2507	5g	$319
2-Chloro-5-nitropyrimidine	C381310	50mg	$45
More product size

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2-Chloro-5-nitropyrimidine Properties

Melting point	105-110 °C
Boiling point	345.4±15.0 °C(Predicted)
Density	1.600±0.06 g/cm3(Predicted)
storage temp.	-20°C
pka	-4.60±0.22(Predicted)
form	powder to crystal
color	Light orange to Yellow to Green
InChI	InChI=1S/C4H2ClN3O2/c5-4-6-1-3(2-7-4)8(9)10/h1-2H
InChIKey	OFCBNMYNAHUDGE-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=C([N+]([O-])=O)C=N1
CAS DataBase Reference	10320-42-0(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	PN2GZ55G8R
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H315-H317-H318-H335

Precautionary statements

P280-P301+P312+P330-P302+P352-P305+P351+P338+P310

target organs

Respiratory system

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-43-41-37/38-22-20/21/22

Safety Statements

26-36-37/39-36/37/39-36/37-24/25

RIDADR

UN 3335

WGK Germany

RTECS

US7175000

HazardClass

IRRITANT

HS Code

29335990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
Skin Sens. 1
STOT SE 3

NFPA 704

	0
2		0

2-Chloro-5-nitropyrimidine price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	720348	2-Chloro-5-nitropyrimidine 97%	10320-42-0	250mg	$101	2023-06-20	Buy
Sigma-Aldrich	720348	2-Chloro-5-nitropyrimidine 97%	10320-42-0	1g	$209	2023-06-20	Buy
TCI Chemical	C2507	2-Chloro-5-nitropyrimidine >98.0%(GC)	10320-42-0	1g	$65	2025-07-31	Buy
TCI Chemical	C2507	2-Chloro-5-nitropyrimidine >98.0%(GC)	10320-42-0	5g	$319	2025-07-31	Buy
TRC	C381310	2-Chloro-5-nitropyrimidine	10320-42-0	50mg	$45	2021-12-16	Buy

Product number	Packaging	Price	Buy
720348	250mg	$101	Buy
720348	1g	$209	Buy
C2507	1g	$65	Buy
C2507	5g	$319	Buy
C381310	50mg	$45	Buy

2-Chloro-5-nitropyrimidine Chemical Properties,Uses,Production

Chemical Properties

Light yellow solid

Uses

2-Chloro-5-nitropyrimidine is an advanced intermediate for kinase/PRMT1 inhibitors, antiviral drugs, and other purine drugs. It can also be converted into herbicides, fungicides, and insecticides, providing targeted crop protection while maintaining good environmental friendliness.

Synthesis

540-80-7

3073-77-6

7447-39-4

10320-42-0

Example 1 Preparation of 2-chloro-5-nitropyrimidine: 5-nitropyrimidin-2-amine (0.98 g, 7 mmol, 1 eq.) was added to a solution of acetonitrile containing anhydrous copper(II) chloride (1.12 g, 8.4 mmol, 1.2 eq.), tert-butyl nitrite (1.24 mL, 10.5 mmol, 1.5 eq.), and MgSO4 (~300 mg) ( 40 mL) solution, and the reaction was stirred at 65-80 °C (bath temperature).After 30 min, the reaction mixture was cooled to room temperature and ether (100 mL) was added. The organic layer was separated and washed sequentially with aqueous 1N HCl (2 x 20 mL), H2O (50 mL) and brine (20 mL). The organic layer was dried over anhydrous Na2SO4 and concentrated under reduced pressure. The crude product was purified by column chromatography (eluent: hexane/ether=3:1) to afford the target product 2-chloro-5-nitropyrimidine as a light yellow solid (0.56 g, 50% yield).

References

[1] Patent: US2003/181465, 2003, A1

2-Chloro-5-nitropyrimidine Preparation Products And Raw materials

Raw materials

Heptane Ethanol Piperidine Phosphorus oxitrichloride Urea

Carbon tetrachloride Sodium nitrite Guanidine hydrochloride Benzene Ethyl acetate

Methanol Sodium hydroxide Mucobromic acid

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Preparation Products

2-methoxy-5-nitropyrimidine

2-Chloro-5-nitropyrimidine Suppliers

Global( 393)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Jinan Zhonghan Chemical Technology Co., LTD.	+undefined15066662237	3281004549@qq.com	China	291	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58

Supplier	Advantage
Wuhan Topule Biopharmaceutical Co., Ltd	58
Jinan Zhonghan Chemical Technology Co., LTD.	58
Capot Chemical Co.,Ltd.	60
Shanghai Time Chemicals CO., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Accela ChemBio Inc.	58
Hubei xin bonus chemical co. LTD	58

View Lastest Price from 2-Chloro-5-nitropyrimidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	2-Chloro-5-nitropyrimidine 10320-42-0	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2025-04-04	2-Chloro-5-nitropyrimidine 10320-42-0	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2019-12-20	2-Chloro-5-nitropyrimidine 10320-42-0	US $0.00 / g	1g	95%min	20kg/month	Nanjing jinheyou Trading Co., Ltd.

2-Chloro-5-nitropyrimidine
10320-42-0
US $1.10 / g
99.00%
Dideu Industries Group Limited

2-Chloro-5-nitropyrimidine
10320-42-0
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

2-Chloro-5-nitropyrimidine
10320-42-0
US $0.00 / g
95%min
Nanjing jinheyou Trading Co., Ltd.

2-Chloro-5-nitropyrimidine Spectrum

2-Chloro-5-nitropyrimidine(10320-42-0)¹HNMR 2-Chloro-5-nitropyrimidine(10320-42-0)FT-IR

10320-42-0(2-Chloro-5-nitropyrimidine)Related Search:

2-Chloro-5-nitropyrimidine-4-amine,4-AMINO-2-CHLORO-5-NITROPYRIMIDINE 2,4,6-TRICHLORO-5-NITROPYRIMIDINE 2-Chloro-5-nitropyrimidine 2,4-Dichloro-6-methyl-5-nitropyrimidine 2,4-Dichloro-5-nitropyrimidine

5-Chloro-2-nitropyridine 2-Chloro-4-nitropyridine 2-Amino-6-chloro-3-nitropyridine 4,6-Dichloro-5-nitropyrimidine 2-Chloro-3-nitropyridine

4-CHLORO-5-NITROPYRIMIDINE Methyl 2-(2-chloro-5-nitropyrimidin-4-ylamino)acetate 4-Chloro-3-nitropyridine 4,6-Dichloro-2-methyl-5-nitropyrimidine 2-Chloropyrimidine

ETHYL 2,6-DICHLORO-5-NITROPYRIMIDINE-4-CARBOXYLATE 2-chloro-N-methyl-5-nitropyrimidin-4-amine 2-CHLORO-6-METHYL-5-NITRO-4(1H)-PYRIMIDINONE

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2-Chloro-5-nitro-1,3-diazine 2-CHLORO-5-NITRO- 2-CHLORO-5-NITROPYRIMIDINE CHLORO(2-)-5-NITROPYRIDINE 2-Chloro-5-nitropyrimidine 98% PYRIDINE, 2-CHLORO-5-NITRO- PYRIMIDINE, 2-CHLORO-5-NITRO- 2-Chloro-5-nitropyrimidine ,98% 2-Chloro-5-nitropyrimidine > 2-Chloro-5-nitropyrimidine ISO 9001：2015 REACH 10320-42-0 C4H2N3O2Cl C4H2ClN3O2 Chloropyridines Halopyridines Heterocycle-Pyrimidine series FINE Chemical & INTERMEDIATES Pyridines, Pyrimidines, Purines and Pteredines pharmacetical Pyrimidine series Pyrazines, Pyrimidines & Pyridazines