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ChemicalBook >> CAS DataBase List >>N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine

N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine

N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine Structure
N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine structure
CAS No.
210344-99-3
Chemical Name:
N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine
Synonyms
Ac-Trp-Glu-His-Asp-AFC trifluoroacetate salt;Caspase 1 (ICE) Substrate 3f, fluorogenic - 5 mg;N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine;L-α-Asparagine, N-acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-;N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine, CAS 210344-99-3;(4S,7S,10S,13S)-10-((1H-Imidazol-4-yl)methyl)-4-((1H-indol-3-yl)methyl)-7-(2-carboxyethyl)-2,5,8,11-tetraoxo-13-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-3,6,9,12-tetraazapentadecan-15-oic acid
CBNumber:
CB73124522
Molecular Formula:
C38H37F3N8O11
Molecular Weight:
838.74
MDL Number:
MFCD01862607
MOL File:
210344-99-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:17
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N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine Properties

Boiling point 1351.5±65.0 °C(Predicted)
Density 1.528±0.06 g/cm3(Predicted)
pka 4.07±0.10(Predicted)
Appearance White to yellow Solid

N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14992 Ac-WEHD-AFC ≥95% 210344-99-3 1mg $69 2021-12-16 Buy
Cayman Chemical 14992 Ac-WEHD-AFC ≥95% 210344-99-3 5mg $173 2021-12-16 Buy
Usbiological 458010 N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine 210344-99-3 1mg $326 2026-06-03 Buy
Usbiological 458010 N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine 210344-99-3 2.5mg $475 2026-06-03 Buy
Biosynth FA110614 Ac-Trp-Glu-His-Asp-AFC trifluoroacetate salt 210344-99-3 25mg $900 2026-06-04 Buy
Product number Packaging Price Buy
14992 1mg $69 Buy
14992 5mg $173 Buy
458010 1mg $326 Buy
458010 2.5mg $475 Buy
FA110614 25mg $900 Buy

N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine Chemical Properties, Uses, Production

Description

Ac-WEHD-AFC is a fluorogenic substrate for group I caspases including caspase-1, -4, and -5. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.

Uses

N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine is a fluorogenic substrate that can be cleaved by group I caspases.

IC 50

Caspase-1

Excitation / Emission Maximum

400 nm/505 nm

Sequene

Ac-Trp-Glu-His-Asp-Unk

N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine Preparation Products And Raw materials

Raw materials

Preparation Products

N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine Suppliers

Global Suppliers ( 33)
Supplier Tel Email Country ProdList Advantage
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799 Eric@peptidego.com China 7872 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 sales@sarms4muscle.com China 10378 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Nanjing chengqimei Biotechnology Co., Ltd 19850819832 2173594524@qq.com China 2638 58
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14072 58
Nanjing TGpeptide Biotechnology Co.,Ltd. 18115476705 sales@tgpeptide.com China 3058 58
Ontores Biotech 0571-88760729 18072970094 supports@ontorespeptide.com China 2696 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
Supplier Advantage
Hangzhou Peptidego Biotech Co.,Ltd. 58
BOC Sciences 58
Zhejiang J&C Biological Technology Co.,Limited 58
Career Henan Chemica Co 58
Nanjing chengqimei Biotechnology Co., Ltd 58
Wuxi Helen Biotechnology Co., Ltd., 58
Nanjing TGpeptide Biotechnology Co.,Ltd. 58
Ontores Biotech 58
Energy Chemical 58
MedBioPharmaceutical Technology Inc 58

210344-99-3 (N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine) Related Search:

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N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine Ac-Trp-Glu-His-Asp-AFC trifluoroacetate salt L-α-Asparagine, N-acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- Caspase 1 (ICE) Substrate 3f, fluorogenic - 5 mg N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine, CAS 210344-99-3 (4S,7S,10S,13S)-10-((1H-Imidazol-4-yl)methyl)-4-((1H-indol-3-yl)methyl)-7-(2-carboxyethyl)-2,5,8,11-tetraoxo-13-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-3,6,9,12-tetraazapentadecan-15-oic acid 210344-99-3 C38H37F3N8O11