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4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride structure

CAS No.: 106261-49-8

Chemical Name:: 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride

Synonyms: benzoic acid dihydrochloride;4-(4-Methyl piperizino methyl) benzoic acid dihydrochloride;4-[(4-Methyl-1-piperazinyl)methyl]benzoic acid dihydrochloride;4-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZOIC ACID DIHYDROCHLORIDE HEMIHYDRATE;Imamic acid;Imatinib Imp.S DiHCl;Imatinib Intermediate 2;IMatinib Carboxylic IMpurity;IMatinib Mesylate InterMediate;4-(4-Methylpiperzinomethyl)benzoic acid.2HCl

CBNumber:: CB7314148

Molecular Formula:: C13H20Cl2N2O2

Molecular Weight:: 307.22

MDL Number:: MFCD08060469

MOL File:: 106261-49-8.mol

MSDS File:: SDS

Last updated:2026-01-12 17:28:22

Product description	Number	Pack Size	Price
4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride >98.0%(HPLC)	M2110	5g	$99
4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride >98.0%(HPLC)	M2110	25g	$348
4-(4-Methylpiperazinomethyl)benzoicAcid,Dihydrochloride	M325921	1g	$95
4-(4-Methylpiperazinomethyl)benzoicAcid,DiHCl	52342	25g	$2120
4-(4-Methylpiperazinomethyl)benzoicacid2HCl	X2630	100g	$147
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4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride Properties

Melting point	305-307°C
storage temp.	Inert atmosphere,Room Temperature
Water Solubility	Soluble in water
solubility	Methanol (Slightly, Heated), Water (Slightly)
form	powder to crystal
color	White to Almost white
Stability	Hygroscopic
InChI	InChI=1S/C13H18N2O2.2ClH.H2O/c1-14-6-8-15(9-7-14)10-11-2-4-12(5-3-11)13(16)17;;;/h2-5H,6-10H2,1H3,(H,16,17);2*1H;1H2
InChIKey	ISHROKOWRJDOSN-UHFFFAOYSA-N
SMILES	C(O)(=O)C1=CC=C(C=C1)CN1CCN(CC1)C.Cl.Cl.O
LogP	0.6
CAS DataBase Reference	106261-49-8(CAS DataBase Reference)
FDA UNII	DJ6E7RG2D9

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H334-H315-H302-H319
Precautionary statements	P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P261-P285-P304+P341-P342+P311-P501-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	22-26-36/37/39
HS Code	2933.59.8000

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M2110	4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride >98.0%(HPLC)	106261-49-8	5g	$99	2026-03-19	Buy
TCI Chemical	M2110	4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride >98.0%(HPLC)	106261-49-8	25g	$348	2026-03-19	Buy
TRC	M325921	4-(4-Methylpiperazinomethyl)benzoicAcid,Dihydrochloride	106261-49-8	1g	$95	2021-12-16	Buy
Medical Isotopes, Inc.	52342	4-(4-Methylpiperazinomethyl)benzoicAcid,DiHCl	106261-49-8	25g	$2120	2021-12-16	Buy
AK Scientific	X2630	4-(4-Methylpiperazinomethyl)benzoicacid2HCl	106261-49-8	100g	$147	2021-12-16	Buy

Product number	Packaging	Price	Buy
M2110	5g	$99	Buy
M2110	25g	$348	Buy
M325921	1g	$95	Buy
52342	25g	$2120	Buy
X2630	100g	$147	Buy

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

4-(4-Methylpiperazinomethyl)benzoic Acid, Dihydrochloride (cas# 106261-49-8) is a compound useful in organic synthesis.

Synthesis

P-cyanobenzyl chloride (1 g, 6.6 mmol) was dissolved in a mixed solvent of ethanol and water (10 mL, ethanol:water in mixed solvent = 2:1), methyl piperazine (1.2eq, 0.792 g, 7.92 mmol) was added, and the reaction was heated at 70 C for 1-2 h. After the reaction was completed, the reaction was cooled down to room temperature and most of the ethanol was recovered to give 4-(4-methyl-1- Piperazinyl)benzonitrile, add sodium hydroxide (6eq, 1.584g, 39.6mmol), heat the reaction at 70 , wait for the reaction is complete, cool to room temperature, slowly add dilute hydrochloric acid dropwise under an ice bath to pH=1, add sodium chloride to saturation, cool to precipitate a solid, filter, and dry, that is, to obtain 4-(4-methylpiperazin-1-ylmethyl)benzoic acid hydrochloride (2.0g).

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride Suppliers

Global( 473)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1319	58
Hefei TianRui Pharmaceutical Chemical Co., Ltd.	+86-0551-68665055 +86-+86-18616906106	sales@trywchem.com	China	187	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21592	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	340	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29821	58
Klong Industrial Co., Ltd	0086-519-68231162	info@klongchem.com	CHINA	131	58

Supplier	Advantage
Shanghai Yingrui Biopharma Co.,Ltd	58
Hefei TianRui Pharmaceutical Chemical Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
Klong Industrial Co., Ltd	58

View Lastest Price from 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-21	4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride 106261-49-8			0.99		RongNa Biotechnology Co.,Ltd
2026-04-21	4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride 106261-49-8	US $12.00 / KG	1KG	>=99%	100mt	Jinan Finer Chemical Co., Ltd
2025-12-01	4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride 106261-49-8	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride
106261-49-8
0.99
RongNa Biotechnology Co.,Ltd

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride
106261-49-8
US $12.00 / KG
>=99%
Jinan Finer Chemical Co., Ltd

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride
106261-49-8
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride Spectrum

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride(106261-49-8)¹HNMR

106261-49-8(4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride)Related Search:

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4-(Aminomethyl)benzoic acid Kresoxim-methyl 2-(Trifluoromethyl)benzoic acid METSULFURON METHYL 4-(Chloromethyl)benzoic acid

p-Toluic acid Tribenuron methyl N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine Thiophanate-methyl Dihydrochloride

Methyl 4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide N-DESMETHYL IMATINIB

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4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride 0.5 hydrate 4-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZOIC ACID DIHYDROCHLORIDE HEMIHYDRATE 4-[(4-METHYL-1-PIPERAZINYL)METHYL]BENZOIC ACID DIHYDROCHLORIDE HEMIHYDRATE 4-[(4-Methyl-1-piperazinyl)methyl]benzoic acid dihydrochloride 4-[(4-Methyl-1-piperaziny)methyl]benzoic acid 4-[(4-methyl-1-piperizino) methyl]benzoic acid dihydrochloride hemihydrate benzoic acid dihydrochloride Benzoicacid,4-[(4-Methyl-1-piperazinyl)Methyl]-,hydrochloride(1:2) IMatinib Mesylate InterMediate 4-〔 (4Methylpiperazin-l-yl)Methyl〕benzoic acid dihydrochloride 4-[(4-Methyl-1-piperazinyl)Methyl]benzoic acid dichlorohydride heMihydrate 4-[(4-Methylpiperazin-1-yl)Methyl]benzoic acid dihydrochlorid 4-[(4-Methylpiperazin-1-yi)Methyl] benzoic acid dihydrochloride IMatinib Carboxylic IMpurity 4-[(4-Methyl-1-piperaziny)Methyl]benzoic acid dihydrochloride heMihydrate 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dih 4-(4-Methyl-Piperazine-Lylmethyl)-Benzoic Acid 4-((4-Methylpiperazin-1-yl)Methyl)benzoic acid dihydrochloride hydrate 4-(4-Methyl-piperazin-1-ylMethyl)-benzoic acid hydrochloride 4 - ((4-methyl-piperazin-1-yl) methyl) benzoic acid dihydrochloride dihydrate 4-(4-Methyl Piperazino Methyl) Benzoic Acid 2HCl 4-[(4-methyl-1-piperazinyl)methyl]-, hydrochloride (1:2) RE EXPORT OF 4-((4-METHYLPIPERAZIN-1-YL)METHYL)BENZOIC ACID DIHYDROCHLORIDE 4-[(METHYLPIPERAZIN-1-YL)METHYL]BENZOIC ACID DIHYDROCHLORIDE 4-[(4-methyl-1-piperazinyl)methyl]benzoic acid hydrate dihydrochloride methyl]benzoic acid dihydrochloride hemihydrate 4-{4-methylpiperazine-1-yl)methyl} benzoic Acid Dihydrochloride 4-[(4-Methyl-1-piperazinyl)methyl]benzoicAcidDihydrochloride> Imatinib Imp.S DiHCl 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid DiHCl 4-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZOIC ACID 2HCL 4-[(4-Methyl piperazin-1-yl) ethyl]benzoic acid dihydrochloride 4-(4-Methyl piperizino methyl) benzoic acid dihydrochloride -[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride hemihydrate 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochlori... 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochlorideQ: What is 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride Q: What is the CAS Number of 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride Q: What is the storage condition of 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride Q: What are the applications of 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride Imatinib Intermediate 2 4-(4-Methylpiperzinomethyl)benzoic acid.2HCl Imamic acid 4-[(4-Methyl piperazin- 1-yl) ethyl]benzoic acid 4- [(4-methylpiperazin-1-yl) methyl] benzoic acid dihydrochloride (imaric acid) 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride ( Imatinib Intermediate) 4-[(4-Methylpiperazinyl)methyl]benzoic acid dihydrochloride 4-[(4-Methylpiperazin-1-yl)methyl]benzoicaciddihydrochloride(Imatinibacid) 4-[(4-Methylpiperazin-1-yl)methyl]benzoicaciddihydrochloride(Imaticacid) 4-(4-Methylpiperazinomethyl)benzoic acid dihydrochloride 98% 4-(4-Methylpiperazin methyl)benzoic acid dihydrochloride Imatinib Acid impurity??: 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride 106261-49-8 C26H42Cl4N4O5 C13H18N2O22ClH C13H18N2O22HCl Intermediate of Imatinib Aromatics API intermediates