p-iodo-Clonidine (hydrochloride)
- CAS No.
- 108294-57-1
- Chemical Name:
- p-iodo-Clonidine (hydrochloride)
- Synonyms
- N-(2,6-dichloro-4-iodophenyl)-4,5-dihydro-1H-imidazol-2-amine:hydrochloride
- CBNumber:
- CB73152714
- Molecular Formula:
- C9H9Cl3IN3
- Molecular Weight:
- 392.45133
- MDL Number:
- MFCD30186669
- MOL File:
- 108294-57-1.mol
- MSDS File:
- SDS
p-iodo-Clonidine (hydrochloride) price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17177 | p-iodo-Clonidine (hydrochloride) ≥98% | 108294-57-1 | 10mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 17177 | p-iodo-Clonidine (hydrochloride) ≥98% | 108294-57-1 | 25mg | $53 | 2026-04-30 | Buy |
| Cayman Chemical | 17177 | p-iodo-Clonidine (hydrochloride) ≥98% | 108294-57-1 | 50mg | $95 | 2026-04-30 | Buy |
| Biosynth | IEA29457 | p-Iodoclonidine hydrochloride | 108294-57-1 | 100mg | $871 | 2026-06-04 | Buy |
| Biosynth | IEA29457 | p-Iodoclonidine hydrochloride | 108294-57-1 | 250mg | $1420 | 2026-06-04 | Buy |
p-iodo-Clonidine (hydrochloride) Chemical Properties, Uses, Production
Uses
p-Iodoclonidine Hydrochloride is a α2-Adrenergic agonist; and displays a high affinity for the α2-adrenergic receptor.
Biological Activity
p-iodo-clonidine (hydrochloride) is a partial agonist of the alpha 2-adrenergic receptor [1].the adrenergic receptors are g protein-coupled receptors that are targets of the catecholamines, especially norepinephrine and epinephrine. there are two main groups of adrenergic receptors: α receptors and β receptors. α2-adrenergic receptor is a gi coupled receptor, which causes a decrease in neurotransmitter release, as well as a decrease of camp activity resulting in smooth muscle contraction [1].p-iodo-clonidine (hydrochloride) is a partial agonist of the alpha 2-adrenergic receptor. clonidine is an antihypertensive α2-adrenergic receptor agonist. pic had minimal agonist activity in inhibiting adenylate cyclase in platelet membranes through α2-adrenergic receptor, but it increased platelet aggregation induced by adp with ec50 value of 1.5 μm. pic also inhibited epinephrine-induced aggregation with ic50 value of 5.1 μm. pic competed for [3h]bromoxidine binding with ki value of 1.0 nm. pic bound to the alpha 2b-ar in ng-10815 cell membranes with kd value of 0.5 +/- 0.1 nm [1].
References
[1]. gerhardt ma, wade sm, neubig rr. p-[125i]iodoclonidine is a partial agonist at the alpha 2-adrenergic receptor. mol pharmacol. 1990 aug;38(2):214-21.
p-iodo-Clonidine (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
p-iodo-Clonidine (hydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| Energy Chemical | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
