ChemicalBook >> CAS DataBase List >>tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate

tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate

tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate structure

CAS No.: 474645-25-5

Chemical Name:: tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate

Synonyms: tert-Butyl (3R,4S,5S)-4-[(S)-2-[(S)-2-[Fmoc(methyl)amino]-3-methylbutanamido]-N,3-dimethylbutanamido]-3-methoxy-5-methylheptanoate;Tert-butyl 4-[[2-[[2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methoxy-5-methylheptanoate;L-Valinamide,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-(1,1-dimethylethoxy)-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-;(5S,8S,11S,12R)-tert-butyl 11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate;tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate

CBNumber:: CB73167651

Molecular Formula:: C40H59N3O7

Molecular Weight:: 693.91

MDL Number:: MFCD28386981

MOL File:: 474645-25-5.mol

Last updated:2025-07-16 09:55:25

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tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate Properties

Boiling point	800.4±65.0 °C(Predicted)
Density	1.097±0.06 g/cm3(Predicted)
storage temp.	2-8°C, stored under nitrogen
pka	13.77±0.46(Predicted)
Appearance	White to off-white Solid

tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Synthonix	B67295	(5S,8S,11S,12R)-tert-butyl 11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate >98%	474645-25-5	100mg	$160	2026-05-06	Buy
Synthonix	B67295	(5S,8S,11S,12R)-tert-butyl 11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate >98%	474645-25-5	250mg	$290	2026-05-06	Buy
Synthonix	B67295	(5S,8S,11S,12R)-tert-butyl 11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate >98%	474645-25-5	1g	$580	2026-05-06	Buy
Synthonix	B67295	(5S,8S,11S,12R)-tert-butyl 11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate >98%	474645-25-5	500mg	$1080	2026-05-06	Buy
aablocks	AA00ILX1	L-Valinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-(1,1-dimethylethoxy)-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl- 98%	474645-25-5	100mg	$175	2026-05-29	Buy

Product number	Packaging	Price	Buy
B67295	100mg	$160	Buy
B67295	250mg	$290	Buy
B67295	1g	$580	Buy
B67295	500mg	$1080	Buy
AA00ILX1	100mg	$175	Buy

tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate Chemical Properties, Uses, Production

tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate synthesis

Synthesis of tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate from N-Carbobenzyloxy-L-valine

tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate Preparation Products And Raw materials

Raw materials

SXCDYMWHVBJDJZ-ZXHYAQOVSA-N N-Carbobenzyloxy-L-valine tert-butyl (3R,4S,5S)-4-((S)-2-amino-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoate tert-butyl (3R,4S,5S)-4-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoate (3R,4S,5S)-tert-butyl3-methoxy-5-methyl-4-(methylamino)heptanoatehydrochloride

FMOC-L-Valine Piperidine Diethyl cyanophosphonate

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Preparation Products

MonoMethyl auristatin E

tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate Suppliers

Global Suppliers ( 25)

Supplier	Tel	Email	Country	ProdList	Advantage
Tianjin Chempharmatech Co.,Ltd.	022-66211079 13212288319	sales@chempharmatech.com	China	943	55
Shanghai Xingui Biotechnology Co., Ltd.	15121041756	xingui2022@126.com	China	9954	58
Shanghai Yunpun industrial Co.,Ltd	21-61726900 15202122459;	sales@yunpun.com	China	497	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Abydos Scientific	18936879710 18851749494	sales@abydoscientific.com	China	1000	58
Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd.	19981275275	sales@zsdpharm.com	China	388	58
Jiangsu aikang biomedical research and development co., LTD	025-58859352 17714375163	qzhang@aikonchem.com	China	15525	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8491	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3147	58
Henan Weituxi Chemical Technology Co., Ltd.	0371-63284658 18135795563	3905209149@qq.com	China	9703	58

Supplier	Advantage
Tianjin Chempharmatech Co.,Ltd.	55
Shanghai Xingui Biotechnology Co., Ltd.	58
Shanghai Yunpun industrial Co.,Ltd	58
Amadis Chemical Company Limited	58
Abydos Scientific	58
Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd.	58
Jiangsu aikang biomedical research and development co., LTD	58
Jinan Carbotang Biotech Co.,Ltd.	58
Hangzhou Huarong Pharm Co., Ltd.	58
Henan Weituxi Chemical Technology Co., Ltd.	58

tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate (5S,8S,11S,12R)-tert-butyl 11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate tert-Butyl (3R,4S,5S)-4-[(S)-2-[(S)-2-[Fmoc(methyl)amino]-3-methylbutanamido]-N,3-dimethylbutanamido]-3-methoxy-5-methylheptanoate L-Valinamide,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-(1,1-dimethylethoxy)-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl- Tert-butyl 4-[[2-[[2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methoxy-5-methylheptanoate 474645-25-5 C40H59N3O7