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Atropine sulfate monohydrate

Atropine sulfate monohydrate Structure
Atropine sulfate monohydrate structure
CAS No.
5908-99-6
Chemical Name:
Atropine sulfate monohydrate
Synonyms
ATRAZINE;HYOSCYAMINE SULFATE;α-(hydroxymethyl)-benzeneacetic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate, hydrate (2:1:1);Atropt;Atropsiol;TROPINI SULFAS;AtropineSulfat;ATROPINI SULFAS;atropiniumsulfat;racemic anisodamine
CBNumber:
CB7339477
Molecular Formula:
C17H25NO7S
Molecular Weight:
387.45
MDL Number:
MFCD00074815
MOL File:
5908-99-6.mol
MSDS File:
SDS
Last updated:2026-01-13 11:24:49
Product description Number Pack Size Price
Hyoscyamine sulfate European Pharmacopoeia (EP) Reference Standard H1600000 80 mg $254
Atropine sulfate salt monohydrate ≥97% (TLC), crystalline A0257 5g $121
Atropine sulfate British Pharmacopoeia (BP) Reference Standard BP023 200MG $354
Atropine sulfate European Pharmacopoeia (EP) Reference Standard A1400000 20 mg $175
Atropine sulfate United States Pharmacopeia (USP) Reference Standard 1045009 500mg $501
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Atropine sulfate monohydrate Properties

Melting point 189-192 °C (A)(lit.)
alpha -0.6 º (per USP 25 ºC)
storage temp. Poison room
solubility H2O: soluble2.5g/mL (stable for several days at 4°C.)
form Powder
color white
Water Solubility soluble
Sensitive Light Sensitive
Merck 14,875
BRN 6109275
Stability Hygroscopic
InChI InChI=1/C17H23NO3.H2O4S/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4/h2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4)/t13-,14+,15+,16;
InChIKey VJFQPODMEGSXHC-RIMUKSHENA-N
SMILES O([C@@H]1C[C@@H]2CC[C@@H](N2C)C1)C(=O)C(C1C=CC=CC=1)CO.S(O)(O)(=O)=O |&1:1,3,6,r|
LogP 2.137 (est)
CAS DataBase Reference 5908-99-6(CAS DataBase Reference)
FDA 21 CFR 310.545
FDA UNII 03J5ZE7KA5
UNSPSC Code 12352210
NACRES NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300+H330
Precautionary statements  P301+P310+P330-P304+P340+P310
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  T+
Risk Statements  26/28-43-36/37/38
Safety Statements  23-45-36/37/39-26-1-25
RIDADR  UN 1544 6.1/PG 2
WGK Germany  2
RTECS  CK2455000
F  3-8-10
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29399900
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 2 Inhalation
Acute Tox. 2 Oral
NFPA 704
1
4 1

Atropine sulfate monohydrate price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H1600000 Hyoscyamine sulfate European Pharmacopoeia (EP) Reference Standard 80 mg $254 2026-03-19 Buy
Sigma-Aldrich A0257 Atropine sulfate salt monohydrate ≥97% (TLC), crystalline 5908-99-6 5g $121 2026-03-19 Buy
Sigma-Aldrich BP023 Atropine sulfate British Pharmacopoeia (BP) Reference Standard 5908-99-6 200MG $354 2026-03-19 Buy
Sigma-Aldrich A1400000 Atropine sulfate European Pharmacopoeia (EP) Reference Standard 5908-99-6 20 mg $175 2026-03-19 Buy
Sigma-Aldrich 1045009 Atropine sulfate United States Pharmacopeia (USP) Reference Standard 5908-99-6 500mg $501 2026-03-19 Buy
Product number Packaging Price Buy
H1600000 80 mg $254 Buy
A0257 5g $121 Buy
BP023 200MG $354 Buy
A1400000 20 mg $175 Buy
1045009 500mg $501 Buy

Atropine sulfate monohydrate Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Uses

Atropine sulfate is mydriatic; antispasmodic; used in preanesthetic medication.

Uses

Anticholinergic;Muscarinic antagonist

Uses

mydriatic and anticholinergie agent in ophthalmie preparations and pre-anesthetie medications; antidote to organophosphous insecticides

Application

Atropine sulfate monohydrate is an alkaloid derived from belladonna, a cholinergic receptor antagonist drug, which has been shown to be a competitive non-selective antagonist of central and peripheral mAChR M (muscarinic acetylcholine receptor). It can be used in the treatment of cardiac arrhythmias. Atropine Sulfate is also used as a pharmaceutical reference standard for a variety of analytical applications.

Application

brand name

Atrophate [Veterinary] (Schering-Plough Animal Health); Atropisol (Ciba Vision, US Ophthalmics); Isopto Atropine (Alcon).

General Description

Atropine is isolated from Atropa belladonna, Datura stramonium and Mandragora officinarum. It is a tertiary amine, which acts as a cholinergic receptor antagonist.

Biological Activity

atropine is a competitive antagonist of muscarinic acetylcholine receptor with ic50 values of 2.22±0.60nm, 4.32±1.63nm, 4.16±1.04nm, 2.38±1.07nm and 3.39±1.16nm for m1, m2, m3, m4 and m5, respectively [1].atropine is an antimuscarinic agent and has shown the pharmacological effects because of binding to muscarinic acetylcholine receptors. atropine, the orthosteric antagonist, has been reported to compete with [3h]-nms for all muscarinic subtypes with a potency consistent with the high affinities at the machr subtypes. the ki values are 1.27±0.36nm, 3.24±1.16nm, 2.21±0.53nm, 0.77±0.43nm and 2.84±0.84nm, respectively [1, 2, 3].

References

[1] lebois ep1, bridges tm, lewis lm, dawson es, kane as, xiang z, jadhav sb, yin h, kennedy jp, meiler j, niswender cm, jones ck, conn pj, weaver cd, lindsley cw. discovery and characterization of novel subtype-selective allosteric agonists for the investigation of m(1) receptor function in the central nervous system.acs chem neurosci. 2010;1(2):104-121.
[2] busch h, allen h, anderson dc.effects of atropine and carbachol on labeling of protein fractions of mouse pancreas in vitro.j pharmacol exp ther. 1959 nov; 127:200-4.
[3] feron o1, smith tw, michel t, kelly ra.dynamic targeting of the agonist-stimulated m2 muscarinic acetylcholine receptor to caveolae in cardiac myocytes. j biol chem. 1997 jul 11; 272(28):17744-8.

Atropine sulfate monohydrate Preparation Products And Raw materials

Raw materials

FUMING SULFURIC ACID Atropine DIETHOXYMETHANE L-Hyoscyamine Carbon tetrachloride

Preparation Products

Atropine sulfate monohydrate Suppliers

Global( 441)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong Xuhuang New material CoLTD 		+86-15095020839 +86-17660422208 China 726 58
Wuhan JiyunZen Tech Co., Ltd. 		+86-18062099985 Amyjiyunzen@yeah.net China 672 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21592 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29825 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Shanghai Standard Technology Co., Ltd. 		18502101150 ft-sales@nature-standard.com CHINA 1923 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32469 58
Supplier Advantage
Shandong Xuhuang New material CoLTD 		58
Wuhan JiyunZen Tech Co., Ltd. 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Xiamen AmoyChem Co., Ltd 		58
Shanghai Standard Technology Co., Ltd. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Wuhan ChemNorm Biotech Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from Atropine sulfate monohydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Belladonna Extract pictures 2026-04-11 Belladonna Extract
US $0.00-0.00 / kg 1kg 12%; 40% HPLC no limitation Changsha Staherb Natural Ingredients Co., Ltd.
Atropine sulfate monohydrate pictures 2026-04-11 Atropine sulfate monohydrate
5908-99-6
 US $0.00-0.00 / kg 1kg ≥98% HPLC 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
Atropine sulfate pictures 2026-04-10 Atropine sulfate
5908-99-6
 US $5.00-0.50 / KG 0.10000000149011612KG 99% hplc 5000kg Wuhan JiyunZen Tech Co., Ltd.
  • Belladonna Extract pictures
  • Belladonna Extract
  • US $0.00-0.00 / kg
  • 12%; 40% HPLC
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • Atropine sulfate pictures
  • Atropine sulfate
    5908-99-6
  • US $5.00-0.50 / KG
  • 99% hplc
  • Wuhan JiyunZen Tech Co., Ltd.

Atropine sulfate monohydrate Spectrum

Atropine sulfate monohydrate(5908-99-6)1HNMRAtropine sulfate monohydrate(5908-99-6)Raman

5908-99-6(Atropine sulfate monohydrate)Related Search:

Methylparaben Methyl acrylate Aluminum sulfate 2-Hydroxyphenylacetic acid Sodium sulfate
4-Methoxyphenylacetic acid Atropine Kresoxim-methyl MELIBIOSE Bensulfuron methyl
Ammonium sulfate 4-Hydroxyphenylacetic acid Thiophanate-methyl Methyl sulfate
Atropine sulfate CYCLOHEPTYLAMINE HYOSCYAMINE SULFATE DIHYDRATE,HYOSCYAMINE SULFATE

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Atropsiol 8-methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate sulfate (2:1) hydrate (salt) HYOSCYAMINE SULFATE ATROPINE SULPHATE MONOHYDRATE ATROPINI SULFAS ATROPINE SULFATE MONOHYDRATE ATROPINE SULFATE SALT MONOHYDRATE ALPHA-(HYDROXYMETHYL)BENZENEACETIC ACID 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER MONOHYDRATE TROPINE TROPATE MONOHYDRATE TROPINI SULFAS ATROPINE SULFATE MONOHYDRATE, PH EUR AtropineSulphateGrPuriss AtropineSulphateB.P.ExAtropaBelladonna Atropinesulfatemonohydrate,98% ATROPINE SULFATE 1-HYDRATE ATROPINE SULFATE 1-HYDRATE, POWDER, PHARMA Atropine sulfate monohydrate, 98.50% Benzeneacetic acid, .alpha.-(hydroxymethyl)- (3-endo)-8-methyl-8-azabicyclo3.2.1oct-3-yl ester, sulfate (2:1) (salt), monohydrate ATROPINESULFATE,MONOHYDRATE,CP ATROPINESULFATE,MONOHYDRATE,POWDER,USP HYOSCYAMINE SULFATE(RG) atropine sulfate crystalline Atropine Sulfate (Monohydrate Salt) α-(hydroxymethyl)-benzeneacetic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate, hydrate (2:1:1) Benorilate Solution, 100ppm ATRAZINE ATROPINE SULFATE, MONOHYDRATE USP alpha-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate Atropine Sulfate Hydrate Atropt α-(Hydroxymethyl)benzeneacetic Acid (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester Sulfate Hydrate a-(Hydroxymethyl)benzeneacetic Acid (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester Sulfate Hydrate Atropine sulphate monohydrate, 98+% Tropine tropate, α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester Atropine monohydrate sulfate salt Atropini sulfas, Tropine tropate, α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester [(1S,5R)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate sulfuric acid hydrate a-(Hydroxymethyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester endo-(+/-)-, sulfate (2:1) (salt), monohydrate Benzeneacetic acid, a-(hydroxymethyl)- (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, sulfate (2:1) (salt), monohydrate 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (±)-tropate (ester), sulfate (2:1) salt monohydrate α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester AtropineSulfat Atropine Sulfate (500 mg) racemic anisodamine Atropine sulfate monohydrate,98.5% Atropine Sulfate RS Atropine sulfate CRS Atropine sulfate hydrate (2:1:1) Atropine sulfate monohydrate USP/EP/BP tropine sulfate monohydrate (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate Atropine sulfate (A1400000) [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate Atropine Sulfate (1045009) ATROPINE SULPHATE MONOHYDRATE AR Bis[(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2RS)-3-hydroxy-2-phenylpropanoate] sulfate monohydrate atropiniumsulfat Atropine Sulfate Atropine Sulfate Monohydrate