ChemicalBook >> CAS DataBase List >>1,2,3,4-Tetrahydro-8-hydroxyquinoline

1,2,3,4-Tetrahydro-8-hydroxyquinoline

1,2,3,4-Tetrahydro-8-hydroxyquinoline structure

CAS No.: 6640-50-2

Chemical Name:: 1,2,3,4-Tetrahydro-8-hydroxyquinoline

Synonyms: AKOS BB-8745;Ferroptosis-IN-21;AKOS BBS-00001526;1,2,3,4-TETRAHYDROQUINOLIN-8-OL;1,2,3,4-TETRAHYDRO-8-QUINOLINOL;8-Quinolinol, 1,2,3,4-tetrahydro-;1,2,3,4-TETRAHYDRO-8-HYDROXYQUINOLINE;8-hydroxy-1,2,3,4-Tetrahydro-quinolin;8-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE;1,2,3,4-Tetrahydro-8-hydroxyquinoline ISO 9001：2015 REACH

CBNumber:: CB7345184

Molecular Formula:: C9H11NO

Molecular Weight:: 149.19

MDL Number:: MFCD02656029

MOL File:: 6640-50-2.mol

MSDS File:: SDS

Last updated:2025-08-08 17:45:00

Product description	Number	Pack Size	Price
8-Hydroxy-1,2,3,4-tetrahydroquinoline	H999818	100mg	$75
8-Hydroxy-1,2,3,4-tetrahydroquinoline	W7741	1g	$97
1,2,3,4-Tetrahydro-quinolin-8-ol	010705	500mg	$30
1,2,3,4-Tetrahydro-8-hydroxyquinoline 95+%	P000055954	1g	$38
1,2,3,4-Tetrahydro-quinolin-8-ol	010705	1g	$45
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1,2,3,4-Tetrahydro-8-hydroxyquinoline Properties

Melting point	121-121.5 °C
Boiling point	300.9±31.0 °C(Predicted)
Density	1.141±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	11.17±0.20(Predicted)
form	solid
color	Light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS09
Signal word	Warning
Hazard statements	H320
Precautionary statements	P264-P337+P313-P305+P351+P338
Hazard Codes	Xi,Xn
Risk Statements	22-52
HazardClass	IRRITANT
HS Code	2933499090

1,2,3,4-Tetrahydro-8-hydroxyquinoline price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	H999818	8-Hydroxy-1,2,3,4-tetrahydroquinoline	6640-50-2	100mg	$75	2021-12-16	Buy
AK Scientific	W7741	8-Hydroxy-1,2,3,4-tetrahydroquinoline	6640-50-2	1g	$97	2021-12-16	Buy
Matrix Scientific	010705	1,2,3,4-Tetrahydro-quinolin-8-ol	6640-50-2	500mg	$30	2021-12-16	Buy
Ark Pharm	P000055954	1,2,3,4-Tetrahydro-8-hydroxyquinoline 95+%	6640-50-2	1g	$38	2021-12-16	Buy
Matrix Scientific	010705	1,2,3,4-Tetrahydro-quinolin-8-ol	6640-50-2	1g	$45	2021-12-16	Buy

Product number	Packaging	Price	Buy
H999818	100mg	$75	Buy
W7741	1g	$97	Buy
010705	500mg	$30	Buy
P000055954	1g	$38	Buy
010705	1g	$45	Buy

1,2,3,4-Tetrahydro-8-hydroxyquinoline Chemical Properties,Uses,Production

Chemical Properties

Pink crystals

Synthesis

148-24-3

6640-50-2

The general procedure for the synthesis of 8-hydroxy-1,2,3,4-tetrahydroquinoline from 8-hydroxyquinoline was as follows: 100 mmol of 8-hydroxyquinoline and polymer microspheres Poly (DVB-co-NVP) loaded with 0.7 mmol of rhodium catalyst were added to 500 ml of water and the mixture was transferred to a reactor. The air in the reaction kettle was replaced five times with hydrogen and then filled with hydrogen to atmospheric pressure. The reaction was stirred at room temperature (25°C) and atmospheric pressure (1 atm) for 40 minutes. Upon completion of the reaction, aqueous phase extraction was performed three times, each time using ether as the extraction solvent. All ether extracts were combined and the ether was removed by rotary evaporator to give dry 8-hydroxy-1,2,3,4-tetrahydroquinoline in 95% yield.

References

[1] Chemical Communications, 2013, vol. 49, # 63, p. 7052 - 7054
[2] Patent: CN105884684, 2016, A. Location in patent: Paragraph 0018; 0019
[3] Journal of Organic Chemistry, 2008, vol. 73, # 21, p. 8639 - 8642
[4] Tetrahedron, 2009, vol. 65, # 47, p. 9737 - 9741
[5] Journal of Organometallic Chemistry, 2016, vol. 821, p. 197 - 205

1,2,3,4-Tetrahydro-8-hydroxyquinoline synthesis

Synthesis of 1,2,3,4-Tetrahydro-8-hydroxyquinoline from 5-Chloro-8-hydroxyquinoline

1,2,3,4-Tetrahydro-8-hydroxyquinoline Preparation Products And Raw materials

Raw materials

8-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE 5-Chloro-8-hydroxyquinoline 8-METHOXYQUINOLINE 1,2,3,4-Tetrahydroquinoline Water

Hydrogen Sulfuric acid 8-Hydroxyquinoline o-Anisidine

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Preparation Products

8-hydroxy-decahydroquinoline 1-(8-Hydroxy-3,4-dihydroquinolin-1(2H)-yl)ethanone

1,2,3,4-Tetrahydro-8-hydroxyquinoline Suppliers

Global( 118)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	9548	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30227	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	18895	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58
Career Henan Chemica Co	58
Dideu Industries Group Limited	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from 1,2,3,4-Tetrahydro-8-hydroxyquinoline manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	1,2,3,4-Tetrahydro-8-hydroxyquinoline 6640-50-2	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited
	2024-02-19	1,2,3,4-Tetrahydro-8-hydroxyquinoline 6640-50-2	US $1190.00 / g	1g	98	500 Kg	R&D Scientific Inc.

1,2,3,4-Tetrahydro-8-hydroxyquinoline
6640-50-2
US $1.10 / g
99.00%
Dideu Industries Group Limited

1,2,3,4-Tetrahydro-8-hydroxyquinoline
6640-50-2
US $1190.00 / g
98
R&D Scientific Inc.

1,2,3,4-Tetrahydro-8-hydroxyquinoline Spectrum

1,2,3,4-Tetrahydro-8-hydroxyquinoline(6640-50-2)¹HNMR

6640-50-2(1,2,3,4-Tetrahydro-8-hydroxyquinoline)Related Search:

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7-Hydroxy-1,2,3,4-tetrahydroquinoline 1,2,3,4-TETRAHYDROQUINOLIN-6-OL 5-CHLORO-1,2,3,4-TETRAHYDRO-QUINOLIN-8-OL 8-METHOXY-2,2,4-TRIMETHYL-1,2,3,4-TETRAHYDROQUINOLINE 2,2,4-TRIMETHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-8-OL

Bometolol 1,2,3,4-Tetrahydro-8-hydroxyquinoline Tetrahydro

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1,2,3,4-TETRAHYDRO-8-HYDROXYQUINOLINE 1,2,3,4-TETRAHYDRO-8-QUINOLINOL 1,2,3,4-TETRAHYDROQUINOLIN-8-OL AKOS BBS-00001526 AKOS BB-8745 8-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE 8-hydroxy-1,2,3,4-Tetrahydro-quinolin 8-Quinolinol, 1,2,3,4-tetrahydro- 1,2,3,4-Tetrahydro-8-hydroxyquinoline ISO 9001：2015 REACH Ferroptosis-IN-21 6640-50-2