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ChemicalBook >> CAS DataBase List >>3,6-Dimethoxypyridazine

3,6-Dimethoxypyridazine

3,6-Dimethoxypyridazine Structure
3,6-Dimethoxypyridazine structure
CAS No.
4603-59-2
Chemical Name:
3,6-Dimethoxypyridazine
Synonyms
3,6-Dimethoxypyridazine;Pyridazine, 3,6-diMethoxy-;Pyridazine, 3,6-dimethoxy- (8CI)(9CI)
CBNumber:
CB7353406
Molecular Formula:
C6H8N2O2
Molecular Weight:
140.14
MDL Number:
MFCD00234224
MOL File:
4603-59-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:55
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3,6-Dimethoxypyridazine Properties

Melting point 106 °C(Solv: water (7732-18-5))
Boiling point 297.4±20.0 °C(Predicted)
Density 1.131±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 2.48±0.10(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C6H8N2O2/c1-9-5-3-4-6(10-2)8-7-5/h3-4H,1-2H3
InChIKey HKQOBAGKDBSVEQ-UHFFFAOYSA-N
SMILES C1(OC)=NN=C(OC)C=C1
FDA UNII CD8K2NYA0E

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P302+P352-P362+P364
HS Code  2933998090

3,6-Dimethoxypyridazine price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR909190 3,6-Dimethoxypyridazine >97% 4603-59-2 1g $21 2026-06-04 Buy
Apolloscientific OR909190 3,6-Dimethoxypyridazine >97% 4603-59-2 5g $24 2026-06-04 Buy
Apolloscientific OR909190 3,6-Dimethoxypyridazine >97% 4603-59-2 25g $102 2026-06-04 Buy
Apolloscientific OR909190 3,6-Dimethoxypyridazine >97% 4603-59-2 100g $400 2026-06-04 Buy
Apolloscientific OR909190 3,6-Dimethoxypyridazine >97% 4603-59-2 500g $1987 2026-06-04 Buy
Product number Packaging Price Buy
OR909190 1g $21 Buy
OR909190 5g $24 Buy
OR909190 25g $102 Buy
OR909190 100g $400 Buy
OR909190 500g $1987 Buy

3,6-Dimethoxypyridazine Chemical Properties, Uses, Production

Uses

3,6-Dimethoxypyridazine is used as a pharmaceutical intermediate in the preparation of sulfonylureas and sulfonylthioureas.

Synthesis

Methanol

67-56-1

3,6-Dichloropyridazine

141-30-0

Sodium Methoxide

124-41-4

3,6-DIMETHOXYPYRIDAZINE

4603-59-2

General procedure for the synthesis of 3,6-dimethoxypyridazine from methanol, 3,6-dichloropyridazine and sodium methanol: 3,6-dichloropyridazine (10.0 g, 67.12 mmol) and sodium methanol (9.79 g, 181.23 mmol) were dissolved in methanol (39 mL) and the reaction was heated at 70 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature, diluted with dichloromethane (200 mL) and subsequently washed with water (100 mL x 2). The organic phase was dried over anhydrous magnesium sulfate and concentrated to dryness under reduced pressure to afford the title compound 3,6-dimethoxypyridazine (9.46 g, 101% yield) as a white solid. The crude product could be directly used in the subsequent reaction without further purification. The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 6.91 (s, 2H), 4.05 (s, 6H). Mass spectrometry (APCI) showed m/z = 182 ([M+H]+). HPLC analysis showed a retention time of 1.19 min.

References

[1] Patent: US2008/318943, 2008, A1. Location in patent: Page/Page column 73

3,6-Dimethoxypyridazine Preparation Products And Raw materials

Raw materials

Methanol 3,6-Dichloropyridazine Sodium Methoxide

Preparation Products

3(2H)-Pyridazinone, 6-Methoxy- Pyridazine, 4-chloro-3,6-dimethoxy- 4-Iodo-3,6-dimethoxy-pyridazine

3,6-Dimethoxypyridazine Suppliers

Global Suppliers ( 78)
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Carbott PharmTech Inc. 0535-6385396 info@carbottpharm.com China 996 56
Jinan Trio PharmaTech Co., Ltd. 0531-88811783 sales@trio-pharmatech.com China 1856 62
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
SynAsst Chemical. 021-60343070 China 12731 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Yongye Biotechnology Co., Ltd. 86-021-61559134 15921386130 3423497944@qq.com China 8135 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Nanjing ERan Biological Pharmaceutical Co., Ltd. 13770809694 googlexu_0114@sina.com China 992 58
Shanghai GaoDao Pharmaceutical Co., Ltd. 021-15001867143 15001867143 1095570358@qq.com China 915 55
Supplier Advantage
Energy Chemical 61
Carbott PharmTech Inc. 56
Jinan Trio PharmaTech Co., Ltd. 62
Nanjing Norris-Pharm Technology Co., Ltd 55
SynAsst Chemical. 55
Bide Pharmatech Ltd. 60
Shanghai Yongye Biotechnology Co., Ltd. 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 50
Nanjing ERan Biological Pharmaceutical Co., Ltd. 58
Shanghai GaoDao Pharmaceutical Co., Ltd. 55

View Latest Price from 3,6-Dimethoxypyridazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,6-Dimethoxypyridazine pictures 2022-01-04 3,6-Dimethoxypyridazine
4603-59-2
 1g 98%minGC 500kgs/month Shanghai Rlavie Technology Co ltd

3,6-Dimethoxypyridazine Spectrum

3,6-DIMETHOXYPYRIDAZINE(4603-59-2)1HNMR

4603-59-2 (3,6-Dimethoxypyridazine) Related Search:

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Pyridazine, 3,6-diMethoxy- Pyridazine, 3,6-dimethoxy- (8CI)(9CI) 3,6-Dimethoxypyridazine 4603-59-2