PAPA NONOATE
- CAS No.
- 146672-58-4
- Chemical Name:
- PAPA NONOATE
- Synonyms
- NOC-15;PAPA/NO;PAPA NONATE;PAPA NONOATE;NOC-15 NONOATE;PROPYLAMINE PROPYLAMINE NONOATE;PAPA NONOate, Nitric oxide (NO) donor;3-[[nitroso(oxido)amino]-propylamino]propylazanium;1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-PROPYL-1-TRIAZENE;3-(2-hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine
- CBNumber:
- CB7360963
- Molecular Formula:
- C6H16N4O2
- Molecular Weight:
- 176.22
- MDL Number:
- MFCD00801020
- MOL File:
- 146672-58-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| PAPA NONOate ≥98% | 82140 | 25mg | $47 |
| PAPA NONOate ≥98% | 82140 | 50mg | $87 |
| PAPA NONOate ≥98% | 82140 | 100mg | $163 |
| PAPA NONOate ≥98% | 82140 | 500mg | $574 |
| Papanonoate | 1980AH | 100mg | $279 |
| Boiling point | 277.2±42.0 °C(Predicted) |
|---|---|
| Density | 1.20±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in Water or Ethanol. |
| form | White to off-white solid. |
| pka | 5.55±0.69(Predicted) |
| color | Off-white |
| Stability | Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Solutions are not stable and must be prepared immediately before use. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| NFPA 704 |
|
PAPA NONOATE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 82140 | PAPA NONOate ≥98% | 146672-58-4 | 25mg | $47 | 2024-03-01 | Buy |
| Cayman Chemical | 82140 | PAPA NONOate ≥98% | 146672-58-4 | 50mg | $87 | 2024-03-01 | Buy |
| Cayman Chemical | 82140 | PAPA NONOate ≥98% | 146672-58-4 | 100mg | $163 | 2024-03-01 | Buy |
| Cayman Chemical | 82140 | PAPA NONOate ≥98% | 146672-58-4 | 500mg | $574 | 2023-06-20 | Buy |
| AK Scientific | 1980AH | Papanonoate | 146672-58-4 | 100mg | $279 | 2021-12-16 | Buy |
PAPA NONOATE Chemical Properties,Uses,Production
Description
PAPA NONOate (146672-58-4) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of PAPA NONOate in 0.1 M phosphate buffer at pH 7.4 is 15 minutes at 37°C, or 77 minutes at room temperature.1Dissociation is essentially instantaneous at a pH of 5.0.
Uses
PAPA NONOate is an NO donor which suppresses the caspase apoptotic cascade.
Definition
ChEBI: PAPA NONOate is an alkylamine.
in vivo
PAPA NONOate (100 μM in phosphate buffer) increases the rate of wound healing in rats with diabetes and wound[2].
| Animal Model: | Anesthetized male Sprague-Dawley rats with streptozotocin-induced diabetes and full thickness dermal wound[2] |
| Dosage: | 100 μM |
| Administration: | Wounds received 100 μM PAPA NONOate in phosphate buffer |
| Result: | Increased the wound healing rate in test group. |
References
[1] L K KEEFER. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms.[J]. Methods in enzymology, 1996, 268: 281-293. DOI:10.1016/s0076-6879(96)68030-6
PAPA NONOATE Preparation Products And Raw materials
Raw materials
Preparation Products
PAPA NONOATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 | shenlinxing@macklin.cn | China | 15872 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44895 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
View Lastest Price from PAPA NONOATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-25 | PAPA NONOate
146672-58-4
|
US $49.00 / mg | 98.00% | 10g | TargetMol Chemicals Inc. |
-
- PAPA NONOate
146672-58-4
- US $49.00 / mg
- 98.00%
- TargetMol Chemicals Inc.
