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4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one

4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one structure

CAS No.: 1445994-28-4

Chemical Name:: 4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one

Synonyms: 4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one;7H-Pyrrolo[2,3-c]pyridin-7-one, 4-[5-amino-2-(2,4-difluorophenoxy)phenyl]-1,6-dihydro-6-methyl-

CBNumber:: CB73684101

Molecular Formula:: C20H15F2N3O2

Molecular Weight:: 367.35

MDL Number:

MOL File:: 1445994-28-4.mol

Last updated:2025-04-18 09:52:41

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4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Properties

Boiling point	553.7±50.0 °C(Predicted)
Density	1.418±0.06 g/cm3(Predicted)
pka	14.88±0.40(Predicted)

4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Chemical Properties,Uses,Production

Uses

PROTAC BRD4 ligand-3 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). PROTAC BRD4 ligand-3 can be used for synthesis PROTAC BRD4 Degrader-27 (HY-162875)[1].

References

[1] Kong Y, et al. BRD4-specific PROTAC inhibits basal-like breast cancer partially through downregulating KLF5 expression. Oncogene. 2024 Sep;43(39):2914-2926. DOI:10.1038/s41388-024-03121-1

4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

ABBV-075

4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuxi AppTec	022-59987777 13552403979	jia_guoqiang@wuxiapptec.com	China	22345	58

Supplier	Advantage
Wuxi AppTec	58

4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one 7H-Pyrrolo[2,3-c]pyridin-7-one, 4-[5-amino-2-(2,4-difluorophenoxy)phenyl]-1,6-dihydro-6-methyl- 1445994-28-4