ChemicalBook >> CAS DataBase List >>CDC
CDC
- CAS No.
- 132465-11-3
- Chemical Name:
- CDC
- Synonyms
- CDC;Cdkn;CDC 5-LO inhibitor;CDC lipoxygenase inhibitor;-3,4-dihydroxy-α-cyanocinnamate;Cinnamyl-3,4-dihydroxy-α-cyanocinnamate;CINNAMYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMATE;Cinnamyl-3,4-dihydroxy-α-cyanocinnamate（CDC);Cinnamyl 3,4-dihydroxy-alpha-cyanocinnamate CDC;1-Cyclohexy1-3-(3-dimethylamino proply)carbodilimide methiodide
- CBNumber:
- CB7380752
- Molecular Formula:
- C19H15NO4
- Molecular Weight:
- 321.33
- MDL Number:
- MFCD00210839
- MOL File:
- 132465-11-3.mol
- MSDS File:
- SDS
Last updated:2026-05-28 02:27:12
| Product description | Number | Pack Size | Price |
| Cinnamyl-3,4-dihydroxy-α-cyanocinnamate ≥98% (HPLC) | SML0105 | 5mg | $143 |
| Cinnamyl-3,4-dihydroxy-α-cyanocinnamate ≥98% (HPLC) | SML0105 | 25mg | $584 |
| Cinnamyl-3,4-dihydroxy-α-Cyanocinnamate ≥97% | 10858 | 5mg | $39 |
| Cinnamyl-3,4-dihydroxy-α-Cyanocinnamate ≥97% | 10858 | 10mg | $74 |
| Cinnamyl-3,4-dihydroxy-α-Cyanocinnamate ≥97% | 10858 | 50mg | $306 |
| More product size | |||
| Boiling point | 583.9±50.0 °C(Predicted) |
|---|---|
| Density | 1.326±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: ≥15mg/mL |
| pka | 8.75±0.10(Predicted) |
| form | powder |
| color | light yellow to yellow |
| InChI | 1S/C19H15NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-9,11-12,21-22H,10H2/b7-4+,16-11+ |
| InChIKey | XGHYFEJMJXGPGN-UYHGDYIZSA-N |
| SMILES | Oc1ccc(cc1O)\C=C(/C#N)C(=O)OC\C=C\c2ccccc2 |
| NCI Dictionary of Cancer Terms | CDC |
| UNSPSC Code | 12352204 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317-H410 |
| Precautionary statements | P261-P272-P273-P280-P302+P352-P333+P313 |
| Hazard Codes | Xi,N |
| Risk Statements | 43-50/53 |
| Safety Statements | 36/37-60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| HazardClass | 9 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Skin Sens. 1 |
CDC price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0105 | Cinnamyl-3,4-dihydroxy-α-cyanocinnamate ≥98% (HPLC) | 132465-11-3 | 5mg | $143 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML0105 | Cinnamyl-3,4-dihydroxy-α-cyanocinnamate ≥98% (HPLC) | 132465-11-3 | 25mg | $584 | 2023-01-07 | Buy |
| Cayman Chemical | 10858 | Cinnamyl-3,4-dihydroxy-α-Cyanocinnamate ≥97% | 132465-11-3 | 5mg | $39 | 2026-04-30 | Buy |
| Cayman Chemical | 10858 | Cinnamyl-3,4-dihydroxy-α-Cyanocinnamate ≥97% | 132465-11-3 | 10mg | $74 | 2026-04-30 | Buy |
| Cayman Chemical | 10858 | Cinnamyl-3,4-dihydroxy-α-Cyanocinnamate ≥97% | 132465-11-3 | 50mg | $306 | 2026-04-30 | Buy |
CDC Chemical Properties,Uses,Production
Uses
CDC is an inhibitor of 5-LO, 12-LO, and 15-LO.
Biological Activity
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) is a potent and direct inhibitor of 5-LO (5-Lipoxygenase) th at reduces 5-LO activity in cell-free assays. CDC also inhibits 12-LO and 15-LO
in vivo
The high glucose and 12(S)-hydroxyeicosatetraenoic acid (HETE) could alter vascular endothelial (VE)-cadherin and β‐catenin phosphorylation levels, but did not alter total protein expression. However, the 12/15-LO inhibitor, Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), antagonized the effect of high glucose on protein phosphorylation to mitigate destruction of the endothelial cell barrier, and the mouse diabetes mellitus model further confirmed these conclusions[1].
CDC Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 54)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Shenzhen Shengda Pharma Limited | 755-85269922 +8613424394241 | sales@shengdapharm.com | CHINA | 310 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19956 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from CDC manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-12 | cdc | $3500.00 | 1KG | 99.8% | 500KG | .GZ HONESTCHEM CO.,LTD | |
 |
2026-06-12 | CDC | $1.00 | 1G | 99.9% | 500KG | .GZ HONESTCHEM CO.,LTD | |
 |
2026-05-11 | Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
132465-11-3
|
$99.00 | 10g | TargetMol Chemicals Inc. |
-
- cdc
- $3500.00
- 99.8%
- .GZ HONESTCHEM CO.,LTD
-
- CDC
- $1.00
- 99.9%
- .GZ HONESTCHEM CO.,LTD
-
- Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
132465-11-3
- $99.00
- TargetMol Chemicals Inc.
132465-11-3(CDC)Related Search:
CINNAMYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMATE
CDC
(E,Z)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid 3-phenyl-2-propenyl ester
Cinnamyl 3,4-dihydroxy-alpha-cyanocinnamate
CDC
1-Cyclohexy1-3-(3-dimethylamino proply)carbodilimide methiodide
-3,4-dihydroxy-α-cyanocinnamate
2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, 3-phenyl-2-propen-1-yl ester, (2E)-
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CDC 5-LO inhibitor
CDC lipoxygenase inhibitor
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate（CDC)
Cdkn
132465-11-3
C19H15NO4
