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2,5-Dimethoxynaphthalene

CAS No.
3900-49-0
Chemical Name:
2,5-Dimethoxynaphthalene
Synonyms
NSC 167477;Rotigotine Impurity 16;Rotigotine Impurity 29;3,8-DiMethoxynaphthalene;1,6-DIMETHOXYNAPHTHALENE;1,6-DimethoxylNaphthalene;2,5-DIMETHOXY NAPHTHALENE;2,5-diMethoxylnaphthalene;Naphthalene, 1,6-diMethoxy-;2,5(1,6)-Dimethoxy Naphthalene
CBNumber:
CB7398751
Molecular Formula:
C12H12O2
Molecular Weight:
188.22
MDL Number:
MFCD00086330
MOL File:
3900-49-0.mol
MSDS File:
SDS
Last updated:2026-05-28 02:57:50
Product description Number Pack Size Price
1,6-Dimethoxynaphthalene 97% 579254 5g $199
1,6-Dimethoxynaphthalene FD22206 10g $199.7
1,6-Dimethoxynaphthalene FD22206 25g $435.5
1,6-Dimethoxynaphthalene FD22206 50g $816.5
1,6-Dimethoxynaphthalene FD22206 100g $1271
More product size

2,5-Dimethoxynaphthalene Properties

Melting point 56-60 °C(lit.)
Boiling point 123°C 0,8mm
Density 1.097±0.06 g/cm3(Predicted)
Flash point 123°C/0.8mm
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Dichloromethane
form Solid
color Brown
BRN 1945987
InChI 1S/C12H12O2/c1-13-10-6-7-11-9(8-10)4-3-5-12(11)14-2/h3-8H,1-2H3
InChIKey RBUFUWIWCCOVOS-UHFFFAOYSA-N
SMILES COc1ccc2c(OC)cccc2c1
CAS DataBase Reference 3900-49-0(CAS DataBase Reference)
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  41
Safety Statements  26-36/39
WGK Germany  3
HS Code  2909309090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Dam. 1
NFPA 704
1
0 0

2,5-Dimethoxynaphthalene price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 579254 1,6-Dimethoxynaphthalene 97% 3900-49-0 5g $199 2023-06-20 Buy
Biosynth FD22206 1,6-Dimethoxynaphthalene 3900-49-0 10g $199.7 2026-06-04 Buy
Biosynth FD22206 1,6-Dimethoxynaphthalene 3900-49-0 25g $435.5 2026-06-04 Buy
Biosynth FD22206 1,6-Dimethoxynaphthalene 3900-49-0 50g $816.5 2026-06-04 Buy
Biosynth FD22206 1,6-Dimethoxynaphthalene 3900-49-0 100g $1271 2026-06-04 Buy
Product number Packaging Price Buy
579254 5g $199 Buy
FD22206 10g $199.7 Buy
FD22206 25g $435.5 Buy
FD22206 50g $816.5 Buy
FD22206 100g $1271 Buy

2,5-Dimethoxynaphthalene Chemical Properties,Uses,Production

Chemical Properties

Brown Solid

Uses

Intermediate in the production of tetralin derivatives

Synthesis

1,6-Dihydroxynaphthalene

575-44-0

Iodomethane

74-88-4

2,5-Dimethoxynaphthalene

3900-49-0

In a round-bottomed flask equipped with a magnetic stirrer, 1.6 g (10.0 mmol) of 1,6-dihydroxynaphthalene (compound 39, purchased from Tokyo Chemical Industry Co., Ltd.) was dissolved in 15 mL of N,N-dimethylformamide (DMF). Subsequently, 14.2 g (100.0 mmol) of iodomethane (purchased from Wako Pure Chemical Industries, Ltd.) and 13.8 g (100.0 mmol) of potassium carbonate (purchased from Wako Pure Chemical Industries, Ltd.) were added to the solution. The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the reaction mixture was extracted by adding dichloromethane and water to the reaction mixture and the organic layer was separated and washed with distilled water. The solvent was removed by distillation under reduced pressure to give 1.7 g (yield: 90%) of 2,5-dimethoxynaphthalene (compound 40) as a colorless liquid.

References

[1] Patent: US2017/342031, 2017, A1. Location in patent: Paragraph 0643

575-44-0
74-88-4
3900-49-0
Synthesis of 2,5-Dimethoxynaphthalene from 1,6-Dihydroxynaphthalene and Iodomethane
Global( 231)Suppliers
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View Lastest Price from 2,5-Dimethoxynaphthalene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,5-Dimethoxynaphthalene pictures 2026-08-13 2,5-Dimethoxynaphthalene
3900-49-0
1KG 99% 20 TONS Shenzhen Nexcon Pharmatechs Ltd.
2,5-Dimethoxynaphthalene pictures 2024-08-15 2,5-Dimethoxynaphthalene
3900-49-0
$1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
2,5-Dimethoxynaphthalene pictures 2019-07-06 2,5-Dimethoxynaphthalene
3900-49-0
$2.00 1kg 99% Career Henan Chemical Co

2,5-Dimethoxynaphthalene Spectrum

1,6-DIMETHOXYNAPHTHALENE, 98+% 2,5(1,6)-Dimethoxy Naphthalene 1,6-DimethoxylNaphthalene 1,6-DIMETHOXYNAPHTHALENE 2,5-DIMETHOXY NAPHTHALENE 3,8-DiMethoxynaphthalene NSC 167477 Naphthalene, 1,6-diMethoxy- 2,5-diMethoxylnaphthalene 2,5-Dimethoxynaphthalene ISO 9001:2015 REACH 2,5-Dimethoxynaphthalene(3900-49-0) Rotigotine Impurity 16 Rotigotine Impurity 29 3900-49-0 2234-19-1 Building Blocks Organic Building Blocks Ethers Oxygen Compounds Ethers Organic Building Blocks Oxygen Compounds Aromatics Intermediates Intermediates of Dyes and Pigments FINE Chemical & INTERMEDIATES Naphthalene derivatives