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2-Phenylquinoline

2-Phenylquinoline Structure
2-Phenylquinoline structure
CAS No.
612-96-4
Chemical Name:
2-Phenylquinoline
Synonyms
830g;2-Phenylquinoline;a-Phenylquinoline;Phenylquinoline,99%;2-Phenylquinoline>Phenylquinoline, 99%;Quinoline, 2-phenyl-;2-Phenylquinoline 99%;alpha-Phenylquinoline;2-Phenylquinoline, 99+%
CBNumber:
CB7408748
Molecular Formula:
C15H11N
Molecular Weight:
205.25
MDL Number:
MFCD00011568
MOL File:
612-96-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:19
Product description Number Pack Size Price
2-Phenylquinoline 99% 299650 1g $88.9
2-Phenylquinoline 99% 299650 5g $422
2-Phenylquinoline >98.0%(GC)(T) P2057 1g $49
2-Phenylquinoline >98.0%(GC)(T) P2057 5g $165
2-Phenylquinoline P321030 50mg $60
More product size
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2-Phenylquinoline Properties

Melting point 84-85 °C (lit.)
Boiling point 363 °C
Density 1.1155 (rough estimate)
refractive index 1.6550 (estimate)
storage temp. Sealed in dry,Room Temperature
form Crystalline Powder
pka 4.52±0.10(Predicted)
color White to light yellow
Water Solubility SLIGHTLY SOLUBLE
λmax 258nm(lit.)
InChI 1S/C15H11N/c1-2-6-12(7-3-1)15-11-10-13-8-4-5-9-14(13)16-15/h1-11H
InChIKey FSEXLNMNADBYJU-UHFFFAOYSA-N
SMILES c1ccc(cc1)-c2ccc3ccccc3n2
CAS DataBase Reference 612-96-4(CAS DataBase Reference)
NIST Chemistry Reference Quinoline, 2-phenyl-(612-96-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
HS Code  29334900
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
1 0

2-Phenylquinoline price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 299650 2-Phenylquinoline 99% 612-96-4 1g $88.9 2026-03-19 Buy
Sigma-Aldrich 299650 2-Phenylquinoline 99% 612-96-4 5g $422 2026-03-19 Buy
TCI Chemical P2057 2-Phenylquinoline >98.0%(GC)(T) 612-96-4 1g $49 2026-03-19 Buy
TCI Chemical P2057 2-Phenylquinoline >98.0%(GC)(T) 612-96-4 5g $165 2026-03-19 Buy
TRC P321030 2-Phenylquinoline 612-96-4 50mg $60 2021-12-16 Buy
Product number Packaging Price Buy
299650 1g $88.9 Buy
299650 5g $422 Buy
P2057 1g $49 Buy
P2057 5g $165 Buy
P321030 50mg $60 Buy

2-Phenylquinoline Chemical Properties,Uses,Production

Description

2-Phenylquinoline is the major quinoline alkaloid of Galipea iongiflora, a Bolivian plant used as treatment for cutaneous leishmaniasis. Antinociceptive properties of 2-phenylquinoline isolated from the bark of Galipea iongiflora against different models of pain in mice were evaluated.

Chemical Properties

white to light yellow crystalline powder

Uses

2-Phenylquinoline was used in quantitative structure-activity relationship (QSAR) analyses of estrogen receptor β-selective ligands.

Preparation

Synthesis of 2-phenylquinoline: Quinoline (1.0 g, 7.742 mmol) and phenyl lithium (2.30 mL, 2 M, 23.22 mmol) were reacted according to general procedure. Purification of the residue by silica gel column chromatography (EtOAc:MeOH:Et3N; 10-30:1:1 or PhMe:MeOH:Et3N; 10:1:1) gave 2-phenylquinoline (0.66 g, 42%) as an orange solid.
Aniline (0.140 g, 1.50 mmol) and cinnamaldehyde (0.132 g, 1.00 mmol) were dissolved in toluene in a reaction vial equipped with a magnetic stirrer bar, followed by the addition of K10 (0.50 g). The reaction mixture was heated at a temperature of 110 C for 3 hours. After completion of the reaction, the crude product was purified by column chromatography over silica gel eluting with a mixture of Hexane : Ethyl acetate (20:1) to produce 2-Phenylquinoline as a yellow solid (0.044 g, 21%); (m.p. 82-84 C) (lit. 84-85 °C); Rf 0.67 (20:1 hexane:ethyl acetate);
1H NMR (400 MHz, CDCl3) δH 7.46-7.51 (1H, m, H-4’), 7.53-7.56 (3H, m, H-6, 3’, 5’), 7.73- 7.77 (1H, m, H-7), 7.85 (1H, d, J = 8.31 Hz, H-5), 7.88-7.91 (1H, d, J = 8.31 Hz, H-3), 8.18- 8.27 (4H, m, H-4, 8, 2’, 6’)
13C NMR(400 MHz, CDCl3) δC 119.2 (C-3), 126.7 (C-6), 127.2 (C-4a), 127.5 (C-2’, 6’), 127.9 (C-5), 128.4 (C-3’, 5’), 128.7 (C-4’), 128.9 (C-7, 8), 129.8 (C-4), 130.3 (C-1’), 137.9 (C-8a), 157.2 (C-2)

Synthesis Reference(s)

Synthetic Communications, 23, p. 1959, 1993 DOI: 10.1080/00397919308009854
Chemical and Pharmaceutical Bulletin, 26, p. 3485, 1978 DOI: 10.1248/cpb.26.3485
Journal of the American Chemical Society, 71, p. 2327, 1949 DOI: 10.1021/ja01175a017

2-Phenylquinoline Preparation Products And Raw materials

Raw materials

Phenylmagnesium bromide Quinoline Phenyllithium Bromobenzene 1,4-Dioxane

Preparation Products

2-Phenylquinoline Suppliers

Global( 198)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29820 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10404 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 18895 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
SIMAGCHEM CORP 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Dideu Industries Group Limited 		58

View Lastest Price from 2-Phenylquinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Phenylquinoline pictures 2025-11-18 2-Phenylquinoline
612-96-4
 US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited
2-Phenylquinoline pictures 2025-09-25 2-Phenylquinoline
612-96-4
 US $188.00-1.00 / KG 1KG 99%, 99.5% Sublimated g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2-Phenylquinoline pictures 2019-07-06 2-Phenylquinoline
612-96-4
 US $8.00 / kg 1kg 99% 10TON Career Henan Chemical Co
  • 2-Phenylquinoline pictures
  • 2-Phenylquinoline
    612-96-4
  • US $188.00-1.00 / KG
  • 99%, 99.5% Sublimated
  • Henan Fengda Chemical Co., Ltd

2-Phenylquinoline Spectrum

2-Phenylquinoline(612-96-4)MS2-Phenylquinoline(612-96-4)1HNMR2-Phenylquinoline(612-96-4)IR12-Phenylquinoline(612-96-4)IR22-Phenylquinoline(612-96-4)Raman

612-96-4(2-Phenylquinoline)Related Search:

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1-Phenyl-2-nitropropene 6-Hydroxy-2(1H)-3,4-dihydroquinolinone quinolinium hydrogen sulphate Quinhydrone 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-MethylBr
2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol Pitavastatin calcium 2-Phenylquinolin-4-ol Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate 2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxaldehyde
6,7-DIMETHOXY-1-(3,4,5-TRIETHOXYPHENYL)ISOQUINOLINE 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline Tariquidar

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alpha-Phenylquinoline 2-Phenylquinoline, 99+% Phenylquinoline,99% a-Phenylquinoline 2-Phenylquinoline Phenylquinoline, 99% 2-Phenylquinoline 99% 2-Phenylquinoline, 99+% 1GR 2-Phenylquinoline> 830g Quinoline, 2-phenyl- 2-Phenylquinoline ISO 9001：2015 REACH 612-96-4 C6H5C9H6N C15H11N Building Blocks Quinolines Heterocyclic Building Blocks Heterocyclic Building Blocks Quinolines Building Blocks Quinolines, Quinazolines and derivatives API intermediates