3-Iodobenzoic acid
- CAS No.
- 618-51-9
- Chemical Name:
- 3-Iodobenzoic acid
- Synonyms
- M-IODOBENZOIC ACID;3-Iodobenzoic;Iodobenzoic aci;3-iodo-benzoicaci;m-Iodobenaoicacid;3-IODOBENZOIC ACID;M-IODOBENZIOC ACID;3-lod-benzoic acid;RARECHEM AL BO 0687;3-iodobenzonic acid
- CBNumber:
- CB7421482
- Molecular Formula:
- C7H5IO2
- Molecular Weight:
- 248.02
- MDL Number:
- MFCD00002496
- MOL File:
- 618-51-9.mol
- MSDS File:
- SDS
| Melting point | 185-187 °C(lit.) |
|---|---|
| Boiling point | 337.2±25.0 °C(Predicted) |
| Density | 2.2170 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol |
| form | Powder |
| pka | 3.8(at 25℃) |
| color | White to beige |
| Water Solubility | Soluble in Chloroform and Methanol. Insoluble in water. |
| Sensitive | Light Sensitive |
| BRN | 971088 |
| InChI | InChI=1S/C7H5IO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H,9,10) |
| InChIKey | KVBWBCRPWVKFQT-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=CC(I)=C1 |
| CAS DataBase Reference | 618-51-9(CAS DataBase Reference) |
| FDA UNII | Q4ZCP9G95X |
| NIST Chemistry Reference | Benzoic acid, 3-iodo-(618-51-9) |
| EPA Substance Registry System | Benzoic acid, 3-iodo- (618-51-9) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | T | |||||||||
| HazardClass | IRRITANT, LIGHT SENSITIVE | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
3-Iodobenzoic acid price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 138584 | 3-Iodobenzoic acid 98% | 618-51-9 | 10g | $51.4 | 2025-07-31 | Buy |
| Sigma-Aldrich | 138584 | 3-Iodobenzoic acid 98% | 618-51-9 | 50g | $177 | 2023-06-20 | Buy |
| TCI Chemical | I0052 | 3-Iodobenzoic Acid >98.0%(GC)(T) | 618-51-9 | 5g | $27 | 2025-07-31 | Buy |
| TCI Chemical | I0052 | 3-Iodobenzoic Acid >98.0%(GC)(T) | 618-51-9 | 25g | $81 | 2025-07-31 | Buy |
| Usbiological | 280696 | 3-Iodobenzoic acid | 618-51-9 | 50g | $386 | 2021-12-16 | Buy |
3-Iodobenzoic acid Chemical Properties,Uses,Production
Description
3-Iodobenzoic acid is added as UV absorbing background electrolyte in separation of uncharged cyclodextrins and their derivatives by capillary electrophoresis.3-Iodobenzoic acid was used in solid phase synthesis of γ-turn mimetic library.
Chemical Properties
white to beige powder
Uses
suzuki reaction
Uses
3-Iodobenzoic acid is used in solid phase synthesis of γ-turn mimetic library. It is used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
Uses
3-Iodobenzoic acid was used in solid phase synthesis of γ-turn mimetic library.
Definition
ChEBI: 3-iodobenzoic acid is an iodobenzoic acid with a single iodo substituent placed at the 3-position.
General Description
3-Iodobenzoic acid is added as UV absorbing background electrolyte in separation of uncharged cyclodextrins and their derivatives by capillary electrophoresis.
Synthesis
25487-66-5
618-51-9
The general procedure for the synthesis of 3-iodobenzoic acid from 3-carboxyphenylboronic acid was as follows: arylboronic acid 1 (0.5 mmol) and K2CO3 (1 mmol, 138.0 mg) were added to a 20 mL Schlenk tube fitted with a non-magnetic stir bar. The Schlenk tube was evacuated twice and backfilled with N2. MeCN (2 mL) and I2 (0.75 mmol, 191 mg) were added to the tube at room temperature. The Schlenk tube was sealed and placed in a preheated oil bath at 80 °C for 8-12 h under a stream of N2 gas. After completion of the reaction, the resulting solution was cooled to room temperature. H2O (10 mL) was added, and for the product 3-iodobenzoic acid, 1 M HCl was added to the aqueous solution until the pH reached 2 prior to extraction.The aqueous layer was extracted with EtOAc (3 x 5 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated by rotary evaporation. Finally, the residue was purified by silica gel column chromatography to obtain the target product 3-iodobenzoic acid.
Purification Methods
Crystallise the acid repeatedly from water and EtOH. Sublime it under vacuum at 100o. [Beilstein 9 IV 1033.]
References
[1] Synlett, 2014, vol. 25, # 7, p. 995 - 1000
[2] Chemistry - A European Journal, 2011, vol. 17, # 20, p. 5652 - 5660
3-Iodobenzoic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20202 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | sales03@chemcn.cn | China | 970 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12891 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| BTC Nantong Pharmaceuticals Technology Co.,Ltd | +8618068193575 | sales4@btcpharm.com | China | 251 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
View Lastest Price from 3-Iodobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-03-04 | 3-Iodobenzoic acid
618-51-9
|
US $20.00 / kg | 1kg | 99% | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-02-26 | 3-Iodobenzoic acid
618-51-9
|
US $0.00-0.00 / kg | 1kg | 98% | Kgs | BTC Nantong Pharmaceuticals Technology Co.,Ltd | |
 |
2023-12-24 | 3-Iodobenzoic acid
618-51-9
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 3-Iodobenzoic acid
618-51-9
- US $20.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
-
- 3-Iodobenzoic acid
618-51-9
- US $0.00-0.00 / kg
- 98%
- BTC Nantong Pharmaceuticals Technology Co.,Ltd
-
- 3-Iodobenzoic acid
618-51-9
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
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