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2,3-Dichloro-5-(trifluoromethyl)pyridine

2,3-Dichloro-5-(trifluoromethyl)pyridine structure

CAS No.: 69045-84-7

Chemical Name:: 2,3-Dichloro-5-(trifluoromethyl)pyridine

Synonyms: DCTF;2,3,5-DCTF;5-DCTF;AKOS BBS-00006992;BUTTPARK 45\10-37;TIMTEC-BB SBB006729;2,3-Dichloro-5-(trif;2,3-Dichloro-5-(Trifluoromethy;Gingerol Impurity 3 (8-Gingerol);3-Dichloro-5-trifluoroMethylpyridine

CBNumber:: CB7421992

Molecular Formula:: C6H2Cl2F3N

Molecular Weight:: 215.99

MDL Number:: MFCD00042243

MOL File:: 69045-84-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:13

Product description	Number	Pack Size	Price
2,3-Dichloro-5-(trifluoromethyl)pyridine 97%	366145	25g	$32.1
2,3-Dichloro-5-(trifluoromethyl)pyridine >95.0%(GC)	D2214	25g	$34
2,3-Dichloro-5-(trifluoromethyl)pyridine	D436370	100g	$250
2,3-Dichloro-5-trifluoromethylpyridine	J93502	1kg	$250
2,3-Dichloro-5-trifluoromethylpyridine	FD38402	1kg	$320
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2,3-Dichloro-5-(trifluoromethyl)pyridine Properties

Melting point	8-9 °C
Boiling point	80 °C20 mm Hg(lit.)
Density	1.549 g/mL at 25 °C(lit.)
refractive index	n20/D 1.475(lit.)
Flash point	175 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in Chloroform, Methanol
form	Liquid
pka	-3.34±0.10(Predicted)
Specific Gravity	1.549
color	Clear colorless to yellow
InChI	InChI=1S/C6H2Cl2F3N/c7-4-1-3(6(9,10)11)2-12-5(4)8/h1-2H
InChIKey	ABNQGNFVSFKJGI-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=C(C(F)(F)F)C=C1Cl
CAS DataBase Reference	69045-84-7(CAS DataBase Reference)
FDA UNII	5F2C8LX8IE
EPA Substance Registry System	2,3-Dichloro-5-(trifluoromethyl)pyridine (69045-84-7)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07,GHS09

Signal word

Danger

Hazard statements

H302+H332-H317-H318-H411

Precautionary statements

P273-P280-P301+P312-P302+P352-P304+P340+P312-P305+P351+P338

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xn,N,Xi

Risk Statements

20/22-41-43-51/53-36/37/38

Safety Statements

24-26-37/39-61-36

RIDADR

UN 3082 9/PG 3

WGK Germany

Hazard Note

Irritant

TSCA

TSCA listed

HazardClass

PackingGroup

III

HS Code

29333990

Storage Class

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Dam. 1
Skin Sens. 1

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	2
2		0

2,3-Dichloro-5-(trifluoromethyl)pyridine price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	366145	2,3-Dichloro-5-(trifluoromethyl)pyridine 97%	69045-84-7	25g	$32.1	2023-06-20	Buy
TCI Chemical	D2214	2,3-Dichloro-5-(trifluoromethyl)pyridine >95.0%(GC)	69045-84-7	25g	$34	2026-04-30	Buy
TRC	D436370	2,3-Dichloro-5-(trifluoromethyl)pyridine	69045-84-7	100g	$250	2021-12-16	Buy
AK Scientific	J93502	2,3-Dichloro-5-trifluoromethylpyridine	69045-84-7	1kg	$250	2021-12-16	Buy
Biosynth Carbosynth	FD38402	2,3-Dichloro-5-trifluoromethylpyridine	69045-84-7	1kg	$320	2021-12-16	Buy

Product number	Packaging	Price	Buy
366145	25g	$32.1	Buy
D2214	25g	$34	Buy
D436370	100g	$250	Buy
J93502	1kg	$250	Buy
FD38402	1kg	$320	Buy

2,3-Dichloro-5-(trifluoromethyl)pyridine Chemical Properties,Uses,Production

Chemical Properties

Light yellow liquid

Uses

2,3-Dichloro-5-(trifluoromethyl)pyridine is a reactant that has been used in the synthesis of a 17b-HSD1 inhibitor.

General Description

2,3-Dichloro-5-(trifluoromethyl)pyridine is reported as an intermediate of herbicide. Synthesis of 2,3-dichloro-5-(trifluoromethyl)pyridine has been reported. Palladium-catalyzed monoalkoxycarbonylation of 2,3-dichloro-5-(trifluoromethyl)pyridine has been reported.

Synthesis

2,3-Dichloro-5-(trichloromethyl)pyridine

69045-83-6

2,3-Dichloro-5-(trifluoromethyl)pyridine

69045-84-7

General procedure for the synthesis of 2,3-dichloro-5-trichloromethylpyridine from 2,3-dichloro-5-trichloromethylpyridine: 26.5 g (0.1 mol) of 2,3-dichloro-5-trichloromethylpyridine and 0.2 g of tungsten hexachloride were added to a reactor, which was heated to 170 °C under atmospheric pressure. Subsequently, about 20 g of hydrogen fluoride was slowly added. The reaction was terminated when the composition of the reaction product no longer changed. The unreacted hydrogen fluoride was recovered by condensation and the generated hydrogen chloride was removed by absorption. The reaction solution was cooled to room temperature and then transferred to an autoclave, heated to 180°C, maintained at a pressure of 0.2 MPa, and reacted for 5 hours. After completion of the reaction, the reaction mixture was cooled and sampled for analysis. The results showed that the product contained 94% of 2,3-dichloro-5-trifluoromethylpyridine and 92% purity.

References

[1] Patent: CN106397309, 2017, A. Location in patent: Paragraph 0023; 0024; 0025; 0025; 0026-0030
[2] Heterocycles, 1984, vol. 22, # 1, p. 117 - 124
[3] Patent: WO2014/198278, 2014, A1. Location in patent: Page/Page column 8; 9; 12
[4] Patent: CN104557683, 2016, B. Location in patent: Paragraph 0021; 0022
[5] Patent: US4590279, 1986, A

2,3-Dichloro-5-(trifluoromethyl)pyridine Preparation Products And Raw materials

Raw materials

2-Amino-5-methylpyridine 2,3-Dichloro-5-(trichloromethyl)pyridine 2-Chloro-5-trichloromethylpyridine Hydrogen fluoride 2-Chloro-5-methylpyridine

Propanal, 2,2-dichloro-3,3,3-trifluoro- Antimony trifluoride 2,6-Dichloromethyl pyridine hydrochloride Tungsten(VI) Chloride 3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE

Nickel 3-Picoline Nicotinic acid Acrylonitrile

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Preparation Products

3-CHLORO-2-HYDROXY-5-(TRIFLUOROMETHYL)PYRIDINE 2,5,6-TRICHLORO-3-TRIFLUOROMETHYLPYRIDINE 2,6-Dichloro-3-(trifluoromethyl)pyridine 2-(3-chloro-5-(trifluoroMethyl)pyridin-2-yl)ethanaMine 1-[3-CHLORO-5-(TRIFLUOROMETHYL)PYRID-2-YL]PIPERAZINE

2,3-Dichloro-5-(trifluoromethyl)pyridine Suppliers

Global( 482)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shandong Jihui Chemical Co., Ltd.	+8615053042019	sales@jihuichem.com	China	34	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	18895	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5235	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	615	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13843	58
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58

Supplier	Advantage
Shandong Jihui Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Dideu Industries Group Limited	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Nantong Guangyuan Chemicl Co,Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Hi-Tech Chemistry Corp	58

View Lastest Price from 2,3-Dichloro-5-(trifluoromethyl)pyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	2,3-Dichloro-5-(trifluoromethyl)pyridine 69045-84-7	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2026-02-28	2,3-Dichloro-5-(trifluoromethyl)pyridine 69045-84-7	US $0.00-0.00 / kg	1kg	Purity: 99.5%	1000tons	Shandong Jihui Chemical Co., Ltd.
2026-01-04	2,3-Dichloro-5-(trifluoromethyl)pyridine 69045-84-7	US $0.00 / kg	1kg	99.6% min	100tons/month	Hangzhou ICH Biofarm Co., Ltd

2,3-Dichloro-5-(trifluoromethyl)pyridine
69045-84-7
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

2,3-Dichloro-5-(trifluoromethyl)pyridine
69045-84-7
US $0.00-0.00 / kg
Purity: 99.5%
Shandong Jihui Chemical Co., Ltd.

2,3-Dichloro-5-(trifluoromethyl)pyridine
69045-84-7
US $0.00 / kg
99.6% min
Hangzhou ICH Biofarm Co., Ltd

2,3-Dichloro-5-(trifluoromethyl)pyridine Spectrum

2,3-Dichloro-5-(trifluoromethyl)pyridine(69045-84-7)MS 2,3-Dichloro-5-(trifluoromethyl)pyridine(69045-84-7)¹HNMR 2,3-Dichloro-5-(trifluoromethyl)pyridine(69045-84-7)¹³CNMR 2,3-Dichloro-5-(trifluoromethyl)pyridine(69045-84-7)IR1 2,3-Dichloro-5-(trifluoromethyl)pyridine(69045-84-7)Raman

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5,6-Dichloro-alpha,alpha,alpha-trifluoro-3-picoline 2,3- two-5- three fluorineMethyl pyridinechloride 2, 3 - dichloro - 5-3 Methyl pyridine 2,3-Dichloro-5-(trifluoromethyl)pyridine 97% 5-DCTF BUTTPARK 45\10-37 2,3-DICHLORO-5-(TRIFLUOROMETHYL)PYRIDINE 2,3,5-DCTF AKOS BBS-00006992 TIMTEC-BB SBB006729 2,3-Dichloro-5-(Trifluoromethy 2,3-DICHLORO-5-(TRIFLUOROMETHY)PYRIDINE 2,3-Dichloro-5-(trifluoromethyl)pyridine,97% 2,3-Dichloro-5-(trif 3-Dichloro-5-trifluoroMethylpyridine 2,3-Dichloro-5-(trifluoroMethyl)pyridine, 97% 25GR Pyridine, 2,3-dichloro-5-(trifluoroMethyl)- 2,3-Dichloro-5-(trifluoroMethyl)pyridine(DCTF) 2,3-Dichloro-5-(trifluoromethyl)pyridine ,98% 2,3-DICHLORO-5-TRIFLUOROMETHYL PYRIDINE (DCTFP) 2,3-Dichloro-5-(trifluoromethyl)pyridine> Gingerol Impurity 3 (8-Gingerol) DCTF 69045-84-7 69045-85-7 C6H2NCl2F3 C6H3Cl2F3N C6H2Cl2F3N C6H2CI2F3N Pyridines Heterocyclic Building Blocks Halogenated Heterocycles Building Blocks Chloropyridines Halopyridines Pyridine series Chloropyridines Halopyridines C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Halides Pyridines Pyridine Fluorine series alkyl chloride 69045-84-7 john's