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1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE

1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE structure

CAS No.: 29976-82-7

Chemical Name:: 1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE

Synonyms: 2-(2-Hydroxy-5-methylbenzoyl)acetophenone;1-(2-Hydroxy-5-methyl)-3-phenyl-1,3-propanedione;1-(2-hydroxy-5-methylphenyl)-3-phenyl-1,3-propane;1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE;1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPANE-1,3-DIONE;1,3-Propanedione, 1-(2-hydroxy-5-methylphenyl)-3-phenyl-;1-(2-HYDROXY-5-METHYLPHENYL)3-PHENYL-1,3-PROPANEDIONE 97%;1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione,97%;JRH-02803, 1-(2-Hydroxy-5-methylphenyl)-3-phenylpropane-1,3-dione, 97%

CBNumber:: CB7438686

Molecular Formula:: C16H14O3

Molecular Weight:: 254.28

MDL Number:: MFCD00209591

MOL File:: 29976-82-7.mol

Last updated:2025-07-24 18:13:42

Product description	Number	Pack Size	Price
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione	1388AL	250mg	$157
1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPANE-1,3-DIONE 95.00%	COR0000701	1G	$1030.84
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione	1388AL	10g	$2328
1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPANE-1,3-DIONE 95.00%	COR0000701	5G	$4244.63
1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPANE-1,3-DIONE 95.00%	COR0000701	10G	$7882.88
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1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE Properties

Melting point	92-94 °C(lit.)
Boiling point	437.3±35.0 °C(Predicted)
Density	1.201±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	7.97±0.43(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	2914310000

1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AK Scientific	1388AL	1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione	29976-82-7	250mg	$157	2021-12-16	Buy
American Custom Chemicals Corporation	COR0000701	1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPANE-1,3-DIONE 95.00%	29976-82-7	1G	$1030.84	2021-12-16	Buy
AK Scientific	1388AL	1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione	29976-82-7	10g	$2328	2021-12-16	Buy
American Custom Chemicals Corporation	COR0000701	1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPANE-1,3-DIONE 95.00%	29976-82-7	5G	$4244.63	2021-12-16	Buy
American Custom Chemicals Corporation	COR0000701	1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPANE-1,3-DIONE 95.00%	29976-82-7	10G	$7882.88	2021-12-16	Buy

Product number	Packaging	Price	Buy
1388AL	250mg	$157	Buy
COR0000701	1G	$1030.84	Buy
1388AL	10g	$2328	Buy
COR0000701	5G	$4244.63	Buy
COR0000701	10G	$7882.88	Buy

1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE Chemical Properties,Uses,Production

Chemical Properties

yellow crystalline powder or needles

Synthesis

4010-19-9

1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE

29976-82-7

2-Benzoyloxy-5-methylacetophenone (I) (5 g, 19.6 mmol) was reacted with 15 g of powdered hot KOH in 25 ml of pyridine and heated at 100 °C for 30 min. After completion of the reaction, the reaction mixture was slowly poured into pre-cooled and acidified (6N HCl) ice water. Subsequently, the precipitated yellow precipitate was collected by filtration. The resulting solid residue was dried under vacuum. The crude product 1-(2-hydroxy-5-methylphenyl)-3-phenylpropane-1,3-dione (II) was purified by recrystallization from petroleum ether, resulting in yellow bright plate-like crystals. Yield: 75%; mass of isolated product: 3.73 g; melting point: 95 °C (literature value: 94 °C [34]).

References

[1] Journal of the Indian Chemical Society, 2006, vol. 83, # 8, p. 835 - 837
[2] European Journal of Medicinal Chemistry, 2014, vol. 73, p. 195 - 209
[3] Chemistry Letters, 2007, vol. 36, # 4, p. 522 - 523
[4] Journal of Organic Chemistry, 1991, vol. 56, # 26, p. 7292 - 7297
[5] Journal of the Indian Chemical Society, 1986, vol. 63, p. 851 - 853

1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE synthesis

Synthesis of 1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE from 1-(2-Hydroxy-5-methylphenyl)ethanone and Benzoic anhydride

1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE Preparation Products And Raw materials

Raw materials

2-Acetyl-4-Methylphenyl Benzoate Pyridine Potassium hydroxide Benzoic anhydride Ethyl benzoate

1-(2-Hydroxy-5-methylphenyl)ethanone

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Preparation Products

4-METHYL-2-(5-PHENYL-1H-PYRAZOL-3-YL)PHENOL

1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE Suppliers

Global( 45)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4017	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53899	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42934	64
Amatek Scientific Co. Ltd.	0512-56316828 4008675858	sales@amateksci.com	China	9872	55
Cool Pharm, Ltd	021-60455363 18019463053	sales@coolpharm.com	China	12346	58
Aikon International Limited	025-66061636 18013972705	qqyang@aikonchem.com	China	15813	58
SHANGHAI FDC-CHEMICAL CO.,LTD	021-61469567 13482353728	sales@fdc-chemical.com	China	9759	58
Henan Weituxi Chemical Technology Co., Ltd.	0371-63284658 18135795563	2885349392@qq.com	China	9909	58

Supplier	Advantage
Accela ChemBio Inc.	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Amadis Chemical Company Limited	58
Shanghai Hanhong Scientific Co.,Ltd.	64
Amatek Scientific Co. Ltd.	55
Cool Pharm, Ltd	58
Aikon International Limited	58
SHANGHAI FDC-CHEMICAL CO.,LTD	58
Henan Weituxi Chemical Technology Co., Ltd.	58

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1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPANE-1,3-DIONE 1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE 1-(2-hydroxy-5-methylphenyl)-3-phenyl-1,3-propane 1-(2-HYDROXY-5-METHYLPHENYL)3-PHENYL-1,3-PROPANEDIONE 97% 1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione,97% 2-(2-Hydroxy-5-methylbenzoyl)acetophenone JRH-02803, 1-(2-Hydroxy-5-methylphenyl)-3-phenylpropane-1,3-dione, 97% 1,3-Propanedione, 1-(2-hydroxy-5-methylphenyl)-3-phenyl- 1-(2-Hydroxy-5-methyl)-3-phenyl-1,3-propanedione 29976-82-7 HOC6H3CH3COCH2COC6 HOC6H3CH3COCH2COC6H5 C15 to C38 Carbonyl Compounds Building Blocks Ketones Organic Building Blocks C15 to C38 Carbonyl Compounds Ketones