NSC117079
- CAS No.
- 500363-63-3
- Chemical Name:
- NSC117079
- Synonyms
- NSC117079;NSC-117079,NSC117079;1-Amino-9,10-dioxo-4-((3-sulfamoylphenyl)amino)-9,10-dihydroanthracene-2-sulfonic acid;2-Anthracenesulfonic acid, 1-amino-4-[[3-(aminosulfonyl)phenyl]amino]-9,10-dihydro-9,10-dioxo-
- CBNumber:
- CB74668294
- Molecular Formula:
- C20H15N3O7S2
- Molecular Weight:
- 473.48
- MDL Number:
- MFCD29079495
- MOL File:
- 500363-63-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
NSC117079 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | AVA36363 | NSC 117079 | 500363-63-3 | 25mg | $1335.75 | 2026-06-04 | Buy |
| Biosynth | AVA36363 | NSC 117079 | 500363-63-3 | 50mg | $1858 | 2026-06-04 | Buy |
| ChemScene | CS-0016845 | NSC117079 98.39% | 500363-63-3 | 5mg | $173 | 2026-06-04 | Buy |
| ChemScene | CS-0016845 | NSC117079 98.39% | 500363-63-3 | 10mg | $282 | 2026-06-04 | Buy |
| ChemScene | CS-0016845 | NSC117079 98.39% | 500363-63-3 | 25mg | $596 | 2026-06-04 | Buy |
NSC117079 Chemical Properties, Uses, Production
Uses
NSC 117079, is a novel PHLPP inhibitor.
in vivo
A single intraarticular injection of the Phlpp inhibitor NSC117079 attenuates mechanical allodynia and slows articular cartilage degradation in joints with a destabilized meniscus. Animals treated with the Phlpp inhibitor seven weeks after injury maintain normal activity levels, while those in the control group travel shorter distances and are less active three months after the joint injury. NSC117079 also increases production of cartilage extracellular matrix components (glycosaminoglycans and aggrecan) in over 90% of human articular cartilage explants from osteoarthritis patients and increased phosphorylation of Phlpp1 substrates (AKT2, ERK1/2 and PKC) in human articular chondrocytes[1].
NSC117079 Preparation Products And Raw materials
Raw materials
Preparation Products
NSC117079 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 87240 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9769 | 55 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28149 | 68 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5123 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 4566 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
