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ALD-PEG4-PFP

CAS No.
1324007-10-4
Chemical Name:
ALD-PEG4-PFP
Synonyms
ALD-PEG4-PFP;ALD-PEG4-OPFP;Ald-Ph-PEG4-PFP;2,3,4,5,6-Pentafluorophenyl 1-[(4-formylphenyl)formamido]-3,6,9,12-tetraoxapentadecan-15-oate;Propanoic acid, 3-[[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]oxy]-, 2,3,4,5,6-pentafluorophenyl ester
CBNumber:
CB74733835
Molecular Formula:
C25H26F5NO8
Molecular Weight:
563.47
MDL Number:
MFCD22201546
MOL File:
1324007-10-4.mol
Last updated:2025-04-18 09:52:41

ALD-PEG4-PFP Properties

Boiling point 658.6±55.0 °C(Predicted)
Density 1.346±0.06 g/cm3(Predicted)
solubility Soluble in DMSO, DCM, DMF
pka 13.53±0.46(Predicted)

ALD-PEG4-PFP price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm bp-20632 Ald-Ph-PEG4-PFP 98% 1324007-10-4 50MG $180 2026-05-24 Buy
BroadPharm bp-20632 Ald-Ph-PEG4-PFP 98% 1324007-10-4 250MG $540 2026-05-24 Buy
BroadPharm bp-20632 Ald-Ph-PEG4-PFP 98% 1324007-10-4 1G $980 2026-05-24 Buy
BroadPharm bp-20632 Ald-Ph-PEG4-PFP 98% 1324007-10-4 5G $2600 2026-05-24 Buy
Chemenu CM338882 ALD-PEG4-OPFP 95%+ 1324007-10-4 1g $1931 2026-05-26 Buy
Product number Packaging Price Buy
bp-20632 50MG $180 Buy
bp-20632 250MG $540 Buy
bp-20632 1G $980 Buy
bp-20632 5G $2600 Buy
CM338882 1g $1931 Buy

ALD-PEG4-PFP Chemical Properties, Uses, Production

Description

Ald-Ph-PEG4-PFP ester is a PEG linker containing a benzaldehyde and PFP ester group. The PFP ester can be reacted with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chain increases the water solubility of compounds. The benzaldehdye can react with pr aminooxy containing molecules.

Uses

ALD-PEG4-OPFP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

ALD-PEG4-PFP Preparation Products And Raw materials

Raw materials

Preparation Products

ALD-PEG4-PFP Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3925 58
Henan Kehong Biological Technology Co. LTD 0371-86658258 18638736641 info@kehobio.com China 2767 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Abosyn 0512-69561983 13914027025 he_qf@medinoah.com China 3000 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38923 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Taizhou Chuanxu Pharmaceutical Technology Co., Ltd. chuanxupharma@126.co chuanxupharma@126.com China 9982 58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd +8618235132063 sales@tihondan.com China 3766 58
Aladdin Scientific tp@aladdinsci.com United States 50068 58
ALD-PEG4-PFP Ald-Ph-PEG4-PFP ALD-PEG4-OPFP 2,3,4,5,6-Pentafluorophenyl 1-[(4-formylphenyl)formamido]-3,6,9,12-tetraoxapentadecan-15-oate Propanoic acid, 3-[[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]oxy]-, 2,3,4,5,6-pentafluorophenyl ester 1324007-10-4 C25H26F5NO8