(S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID
- CAS No.
- 7013-05-0
- Chemical Name:
- (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID
- Synonyms
- (S)-4-AMINO-3-HYDROXYBUTANOIC ACID;S-(+)-GABOB;β-hydroxy-GABA;beta-hydroxy-GABA;(S)-(+)-3-Hydroxy-GABA;(S)-(+)-β-hydroxy-GABA;GABOB (beta-hydroxy-GABA);D-4-Amino-3-hydroxybutyric acid;(S)-4-AMINO-3-HYDROXYBUTYRIC ACID;(3S)-4-Amino-3-hydroxybutanoic acid
- CBNumber:
- CB7488146
- Molecular Formula:
- C4H9NO3
- Molecular Weight:
- 119.12
- MDL Number:
- MFCD00672884
- MOL File:
- 7013-05-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (S)-(+)-4-Amino-3-hydroxybutyric acid 97% | 542946 | 5g | $469.5 |
| (S)-(+)-4-Amino-3-hydroxybutyric acid 97% | 542946 | 1g | $153 |
| (S)-4-Amino-3-hydroxybutanoic acid 95+% | A32052 | 250mg | $26 |
| (S)-4-Amino-3-hydroxybutanoic acid 95+% | A32052 | 1g | $40 |
| (S)-4-Amino-3-hydroxybutanoic acid 95+% | A32052 | 5g | $180 |
| More product size | |||
| Melting point | 207-212 °C |
|---|---|
| alpha | 20 º (C=1.7 IN H2O) |
| Boiling point | 374.5±32.0 °C(Predicted) |
| Density | 1.312±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 4.04±0.10(Predicted) |
| form | Solid |
| optical activity | [α]20/D +20.0°, c = 1.7 in H2O |
| InChI | InChI=1S/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1 |
| InChIKey | YQGDEPYYFWUPGO-VKHMYHEASA-N |
| SMILES | C(O)(=O)C[C@H](O)CN |
| CAS DataBase Reference | 7013-05-0(CAS DataBase Reference) |
| FDA UNII | CM46XGM78M |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
(S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 542946 | (S)-(+)-4-Amino-3-hydroxybutyric acid 97% | 7013-05-0 | 5g | $469.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 542946 | (S)-(+)-4-Amino-3-hydroxybutyric acid 97% | 7013-05-0 | 1g | $153 | 2023-06-20 | Buy |
| Synthonix | A32052 | (S)-4-Amino-3-hydroxybutanoic acid 95+% | 7013-05-0 | 250mg | $26 | 2026-05-06 | Buy |
| Synthonix | A32052 | (S)-4-Amino-3-hydroxybutanoic acid 95+% | 7013-05-0 | 1g | $40 | 2026-05-06 | Buy |
| Synthonix | A32052 | (S)-4-Amino-3-hydroxybutanoic acid 95+% | 7013-05-0 | 5g | $180 | 2026-05-06 | Buy |
(S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
S-(+)-GABOB anticonvulsant and is used in the treatment of epilepsy as it binds to the GABAB receptor.
General Description
(S)-(+)-4-Amino-3-hydroxybutyric acid [(S)-GABOB] can be prepared starting from ethyl (S)-4-chloro-3-hydroxybutyrate.
Synthesis
amino]-, (3S)-](/CAS/20210305/GIF/1431373-89-5.gif)
1431373-89-5
7013-05-0
GENERAL METHODS: Compound 7 (400 mg, 0.92 mmol) was dissolved in EtOAc (20 mL) and 10% Pd/C (785 mg, 0.74 mmol, 80 mol%) was added. The reaction system was degassed and hydrogenated under 1 atm H2 atmosphere for 12 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford (S)-(+)-4-amino-3-hydroxybutyric acid ((S)-GABOB, 2) (95 mg, 87% yield) as a white solid. The product was purified by recrystallization from EtOH-H2O mixed solvent. Melting point: 200-202°C (literature value 13e: 198-201°C); [α]27D +17.2 (c 1.23, H2O) (literature value 13e: [α]25D +16.7 (c 0.41, H2O)).1H NMR (600 MHz, D2O): δ 2.44 (d, J = 6.6 Hz, 2H), 3.97 (dd J = 13.2, 9.6 Hz, 1H), 3.18 (dd, J = 13.2, 3.0 Hz, 1H), 4.19-4.23 (m, 1H). 13C NMR (150 MHz, D2O): δ 42.3, 44.1, 65.5, 178.6. HRMS (ESI): m/z [M + Na]+ calculated value C4H9NNaO3: 142.0480; measured value: 142.0462. ref 22: Abdel-Magid, A. F.; Carson, K.
References
[1] Tetrahedron Letters, 2013, vol. 54, # 21, p. 2637 - 2640
(S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8591 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29817 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 10000 | 58 |
| Siyang Liaoning Biochemical Products Co. Ltd | +86-15221114306; +8615221114306 | 2594582574@qq.com | China | 561 | 58 |
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 | info@allgreenchem.com | China | 5998 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
View Lastest Price from (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-15 | (S)-(+)-4-Amino-3-hydroxybutyric acid
7013-05-0
|
US $209.00-954.00 / g | 5g | 0.99 | 1kg | Shanghai UCHEM Inc. | |
 |
2019-07-06 | (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID
7013-05-0
|
US $1.00 / KG | 1G | 98% | 100KG | Career Henan Chemical Co |
-
- (S)-(+)-4-Amino-3-hydroxybutyric acid
7013-05-0
- US $209.00-954.00 / g
- 0.99
- Shanghai UCHEM Inc.
-
- (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID
7013-05-0
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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