HCV NS5a
- CAS No.
- Chemical Name:
- HCV NS5a
- Synonyms
- HCV NS5a
- CBNumber:
- CB75733335
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| FDA UNII | 2VGG6P316Y |
|---|
HCV NS5a Chemical Properties,Uses,Production
Description
Recombinant HCV NS5A produced in E. coli is a single polypeptide chain containing 118 amino acids (aa 2210-2306) and having a molecular mass of 13.4kDa.
Recombinant HCV NS5A is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
NS5A is a component of the replication complex which takes part in RNA-binding. NS5A protein’s hyperphosphorylated form is an inhibitor of viral replication. NS5A interacts with Human VAPB and through it targets the viral replication complex to vesicles. NS5A down-regulates viral IRES translation initiation and mediates interferon resistance by interacting and inhibiting human EIF2AK2/PKR. NS5a is also inhibits apoptosis by interacting with BIN1 and FKBP8.
HCV NS5a Preparation Products And Raw materials
Raw materials
Preparation Products
HCV NS5a Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9925 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Yaji Biological Technology Co., Ltd. | 58 |
