ChemicalBook >> CAS DataBase List >>7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID

7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID

CAS No.
128719-90-4
Chemical Name:
7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID
Synonyms
I-BOP;I-BOP >=95% (HPLC);UYFMSCHBODMWON-JCPFAPSOSA-N;7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID;(5Z)-7-[(1S,4R)-3β-[(1E,3R)-3-Hydroxy-4-(p-iodophenoxy)-1-butenyl]-7-oxabicyclo[2.2.1]heptane-2α-yl]-5-heptenoic acid;(5Z)-7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-Hydroxy-4-(4-iodophenoxy)-1-buten-1-yl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid;5-Heptenoic acid, 7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-hydroxy-4-(4-iodophenoxy)-1-buten-1-yl]-7-oxabicyclo[2.2.1]hept-2-yl]-, (5Z)-
CBNumber:
CB7674385
Molecular Formula:
C23H29IO5
Molecular Weight:
512.38
MDL Number:
MFCD00084824
MOL File:
128719-90-4.mol
MSDS File:
SDS
Last updated:2026-01-13 11:23:07
Product description Number Pack Size Price
I-BOP ≥95% (HPLC) SML0504 1mg $541
I-BOP ≥95% (HPLC) SML0504 5mg $2180
I-BOP ≥95% 19600 100μg $84
I-BOP ≥95% 19600 500μg $369
I-BOP ≥95% 19600 1mg $602

7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID Properties

Boiling point 634.5±55.0 °C(Predicted)
Density 1.483±0.06 g/cm3(Predicted)
Flash point 14℃
storage temp. -20°C
solubility DMF: >50 mg/ml (from Pinane TXA2); DMSO: >25 mg/ml (from Pinane TXA2); Ethanol: >100 mg/ml (from Pinane TXA2); PBS (pH 7.2): 3 mg/ml
pka 4.76±0.10(Predicted)
form solution
color colorless to faint yellow
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P305+P351+P338
Hazard Codes  F
Risk Statements  11
Safety Statements  7-16
RIDADR  UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany  2
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 2
NFPA 704
3
0 0

7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0504 I-BOP ≥95% (HPLC) 128719-90-4 1mg $541 2025-07-31 Buy
Sigma-Aldrich SML0504 I-BOP ≥95% (HPLC) 128719-90-4 5mg $2180 2025-07-31 Buy
Cayman Chemical 19600 I-BOP ≥95% 128719-90-4 100μg $84 2024-03-01 Buy
Cayman Chemical 19600 I-BOP ≥95% 128719-90-4 500μg $369 2024-03-01 Buy
Cayman Chemical 19600 I-BOP ≥95% 128719-90-4 1mg $602 2024-03-01 Buy
Product number Packaging Price Buy
SML0504 1mg $541 Buy
SML0504 5mg $2180 Buy
19600 100μg $84 Buy
19600 500μg $369 Buy
19600 1mg $602 Buy

7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID Chemical Properties,Uses,Production

Uses

I-BOP is an agonist for thromboxane A2 receptor (TP) with a KD of 0.61 nM. I-BOP promotes proliferation through activation of PI3K pathway in vascular smooth muscle[1]. I-BOP dose-dependently biphasicly affects the excitatory postsynaptic potential (e.p.s.p.) in hippocampal neurons[2].

Biochem/physiol Actions

I-BOP is a potent thromboxane (TP) receptor agonist. I-BOP induces human platelet aggregation with an EC50 value of 0.34 nM.

References

[1] Morinelli TA, et al., Tyrosine phosphorylation of phosphatidylinositol 3-kinase and of the thromboxane A2 (TXA2) receptor by the TXA2 mimetic I-BOP in A7r5 cells. Biochem Pharmacol. 1997 Jun 15;53(12):1823-32. DOI:10.1016/s0006-2952(97)00005-1
[2] Hsu KS, et al., Thromboxane A2 agonist modulation of excitatory synaptic transmission in the rat hippocampal slice. Br J Pharmacol. 1996 Aug;118(8):2220-7. DOI:10.1111/j.1476-5381.1996.tb15666.x

7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID Suppliers

Global( 41)Suppliers
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TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32470 58
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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
HUNAN CHEMFISH SCIENTIFIC CO.,LTD +86-0731-85567275 17788968862 sales05@chemfish.com China 7571 58
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Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25004 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24963 58

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I-BOP pictures 2026-01-05 I-BOP
128719-90-4
US $2170.00 / mg 10g TargetMol Chemicals Inc.
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128719-90-4(7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID)Related Search:

7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-HYDROXY-4-(4-IODOPHENOXY)-1-BUTENYL]-7-OXABICYCLO[2.2.1]HEPT-2-YL]-5Z-HEPTENOIC ACID I-BOP (5Z)-7-[(1S,4R)-3β-[(1E,3R)-3-Hydroxy-4-(p-iodophenoxy)-1-butenyl]-7-oxabicyclo[2.2.1]heptane-2α-yl]-5-heptenoic acid (5Z)-7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-Hydroxy-4-(4-iodophenoxy)-1-buten-1-yl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid UYFMSCHBODMWON-JCPFAPSOSA-N I-BOP >=95% (HPLC) 5-Heptenoic acid, 7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-hydroxy-4-(4-iodophenoxy)-1-buten-1-yl]-7-oxabicyclo[2.2.1]hept-2-yl]-, (5Z)- 128719-90-4