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4-(2-Aminoethyl)-1-Boc-piperidine

CAS No.
146093-46-1
Chemical Name:
4-(2-Aminoethyl)-1-Boc-piperidine
Synonyms
tert-butyl 4-(2-aminoethyl)piperidine-1-carboxylate;4-(AMINOETHYL)-1-BOC-PIPERIDINE;1-N-Boc-4-(Aminoethyl)-piperidine;4-(2-AMINOETHYL)-1-BOC-PIPERIDINE;4-(AMINOETHYL)-1-N-BOC-PIPERIDINE;4-(2-Aminoethyl)-1-N-Boc-piperidine;4-(Aminoethyl)-1-N-Boc-piperidine Hcl;4-(Aminoethyl)-1-N-Boc-piperidine;4-(2-Aminoethyl)piperidine, N1-BOC protected;4-(Aminoethyl)-1-N-Boc-piperidine - [A13695]
CBNumber:
CB7698541
Molecular Formula:
C12H24N2O2
Molecular Weight:
228.33
MDL Number:
MFCD04038459
MOL File:
146093-46-1.mol
Last updated:2025-09-25 17:15:13
Product description Number Pack Size Price
4-(2-Aminoethyl)-1-boc-piperidine A608030 1g $105
tert-Butyl4-(2-aminoethyl)piperidine-1-carboxylate W3189 1g $105
tert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylate FB139873 100mg $50
4-(Aminoethyl)-1-N-Boc-piperidine 95+% A13695 1g $50
tert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylate FB139873 250mg $80
More product size

4-(2-Aminoethyl)-1-Boc-piperidine Properties

Boiling point 316.0±15.0 °C(Predicted)
Density 1.010±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form semisolid
pka 10.43±0.10(Predicted)
color off-white to light yellow
InChI InChI=1S/C12H24N2O2/c1-12(2,3)16-11(15)14-8-5-10(4-7-13)6-9-14/h10H,4-9,13H2,1-3H3
InChIKey LBQDLHPFISVBRU-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC(CCN)CC1
CAS DataBase Reference 146093-46-1(CAS DataBase Reference)
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  36/37/38-22
Safety Statements  26-36/37/39
RIDADR  UN2811
HazardClass  IRRITANT
HS Code  2933399990
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

4-(2-Aminoethyl)-1-Boc-piperidine price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A608030 4-(2-Aminoethyl)-1-boc-piperidine 146093-46-1 1g $105 2021-12-16 Buy
AK Scientific W3189 tert-Butyl4-(2-aminoethyl)piperidine-1-carboxylate 146093-46-1 1g $105 2021-12-16 Buy
Biosynth Carbosynth FB139873 tert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylate 146093-46-1 100mg $50 2021-12-16 Buy
Synthonix A13695 4-(Aminoethyl)-1-N-Boc-piperidine 95+% 146093-46-1 1g $50 2021-12-16 Buy
Biosynth Carbosynth FB139873 tert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylate 146093-46-1 250mg $80 2021-12-16 Buy
Product number Packaging Price Buy
A608030 1g $105 Buy
W3189 1g $105 Buy
FB139873 100mg $50 Buy
A13695 1g $50 Buy
FB139873 250mg $80 Buy

4-(2-Aminoethyl)-1-Boc-piperidine Chemical Properties,Uses,Production

Synthesis

(1-BOC-piperidin-4-yl)acetonitrile

256411-39-9

4-(2-Aminoethyl)-1-Boc-piperidine

146093-46-1

General procedure for the synthesis of 2-(N-Boc-4-piperidinyl)ethylamine from 1-Boc-4-(cyanomethyl)piperidine: tert-butyl 4-(cyanomethyl)piperidine-1-carboxylate (20 g, 89.29 mmol) and NH4OH (9 mL) were dissolved in methanol (200 mL) and Raney Ni (6 g, 101.69 mmol) was added. The reaction was carried out at 50°C for 5 h under H2 pressure of 50 psi. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was concentrated to afford the target product 2-(N-Boc-4-piperidinyl)ethylamine (20.5 g, 100%) as a colorless oil.1H NMR (400 MHz, CDCl3) δ 1.06-1.19 (m, 2H), 1.44 (d, J = 7.41 Hz, 2H), 1.47 (s 9H), 1.50-1.58 (m, 1H), 1.66 (d, J = 12.49 Hz, 2H), 2.09 (br.s., 2H), 2.70 (t, J = 12.29 Hz, 2H), 2.75-2.83 (m, 2H), 4.08 (br.s., 2H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 21, p. 4805 - 4811

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View Lastest Price from 4-(2-Aminoethyl)-1-Boc-piperidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(2-Aminoethyl)-1-Boc-piperidine pictures 2019-07-06 4-(2-Aminoethyl)-1-Boc-piperidine
146093-46-1
US $1.00 / KG 1KG 98% 100KG Career Henan Chemical Co

4-(2-Aminoethyl)-1-Boc-piperidine Spectrum

4-(AMINOETHYL)-1-BOC-PIPERIDINE 4-(AMINOETHYL)-1-N-BOC-PIPERIDINE 4-(2-Aminoethyl)-1-N-Boc-piperidine tert-butyl 4-(2-aminoethyl)piperidine-1-carboxylate 1-N-Boc-4-(Aminoethyl)-piperidine 1-Piperidinecarboxylic acid, 4-(2-aminoethyl)-, 1,1-dimethylethyl ester 4-(Aminoethyl)-1-N-Boc-piperidine Hcl 4-(AMinoethyl)-1-N-Boc-piperidine/tert-butyl 4-(2-aMinoethyl)piperidine-1-carboxylate 4-(2-AMINO-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-(2-AMINOETHYL)-1-BOC-PIPERIDINE 4-(2-Aminoethyl)piperidine, N1-BOC protected 4-(2-Aminoethyl)piperidin-1-carboxylic acid tert-butyl ester 4-(2-aminoethyl)-1-piperidinecarboxylic acid tert-butyl ester 4-(Aminoethyl)-1-N-Boc-piperidine 4-(Aminoethyl)-1-N-Boc-piperidine - [A13695] 146093-46-1 pharmacetical