ISOQUINOLINE-5-CARBOXYLIC ACID
- CAS No.
- 27810-64-6
- Chemical Name:
- ISOQUINOLINE-5-CARBOXYLIC ACID
- Synonyms
- ine-5-carboxyL;RARECHEM AL BE 1523;5-Carboxyisoquinoline;5-Isoquinolinecarboxylicaci;5-isoquinolinecarboxylic acid;ISOQUINOLINE-5-CARBOXYLIC ACID;Isoquinoline-5-carboxylicacid,96%;ISOQUINOLINE-5-CARBOXYLIC ACID ISO 9001：2015 REACH;5-Carboxyisoquinoline, 2-Azanaphthalene-5-carboxylic acid
- CBNumber:
- CB7720604
- Molecular Formula:
- C10H7NO2
- Molecular Weight:
- 173.17
- MDL Number:
- MFCD03788744
- MOL File:
- 27810-64-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Isoquinoline-5-carboxylic acid 95% | 722626 | 250mg | $51.52 |
| Isoquinoline-5-carboxylic acid | I918013 | 250mg | $55 |
| Isoquinoline-5-carboxylic acid | OR8925 | 1g | $87 |
| Isoquinoline-5-carboxylic acid | 4H21-1-B2 | 1g | $96 |
| Isoquinoline-5-carboxylic acid | OR8925 | 250mg | $29 |
| More product size | |||
| Melting point | 278-281°C |
|---|---|
| Boiling point | 60-62°C 11mm |
| Density | 1.339±0.06 g/cm3(Predicted) |
| Flash point | 60-62°C/11mm |
| storage temp. | 2-8°C(protect from light) |
| pka | 1.21±0.10(Predicted) |
| form | solid |
| Appearance | White to off-white Solid |
| BRN | 129180 |
| InChI | 1S/C10H7NO2/c12-10(13)9-3-1-2-7-6-11-5-4-8(7)9/h1-6H,(H,12,13) |
| InChIKey | ZIPLFLRGHZAXSJ-UHFFFAOYSA-N |
| SMILES | OC(=O)c1cccc2cnccc12 |
| CAS DataBase Reference | 27810-64-6(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-36-22 | |||||||||
| Safety Statements | 26-36/37/39-22 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2933499090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 |
|||||||||
| NFPA 704 |
|
ISOQUINOLINE-5-CARBOXYLIC ACID price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 722626 | Isoquinoline-5-carboxylic acid 95% | 27810-64-6 | 250mg | $51.52 | 2025-07-31 | Buy |
| TRC | I918013 | Isoquinoline-5-carboxylic acid | 27810-64-6 | 250mg | $55 | 2021-12-16 | Buy |
| Apolloscientific | OR8925 | Isoquinoline-5-carboxylic acid | 27810-64-6 | 1g | $87 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H21-1-B2 | Isoquinoline-5-carboxylic acid | 27810-64-6 | 1g | $96 | 2021-12-16 | Buy |
| Apolloscientific | OR8925 | Isoquinoline-5-carboxylic acid | 27810-64-6 | 250mg | $29 | 2021-12-16 | Buy |
ISOQUINOLINE-5-CARBOXYLIC ACID Chemical Properties,Uses,Production
Uses
Isoquinoline-5-carboxylic acid is an isoquinoline derivative. This group of substances can be used as raw materials for organic synthesis in the preparation of other heterocyclic compounds or pharmaceutical products. Studies have shown that its derivative isoquinoline-3-carboxylic acid (IQ3CA) has antimicrobial activity and is a lead compound with antimicrobial properties for plant diseases[1].
Synthesis
27655-41-0
27810-64-6
The general procedure for the synthesis of isoquinoline-5-carboxylic acid from 5-cyanoisoquinoline was as follows: isoquinoline-5-carbonitrile (6 g, 38.62 mmol) prepared in step (1) was mixed with distilled water (90 mL) and stirred until homogeneous. Concentrated hydrochloric acid solution (15 mL) was slowly added to the reaction system, followed by heating the reaction mixture to 100 °C and continuous stirring for 6 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted to 5~6 by dropwise addition of N,N-diisopropylethylamine (DIPEA, ca. 40 mL).The resulting suspension was continued to be stirred at room temperature for 3 hr, followed by diafiltration. The collected solid product was dried in an oven at 50 °C to give final isoquinoline-5-carboxylic acid (5.6 g, 84% yield). Mass spectrum (ESI+, m/z): 174 [M+H]+.
References
[1] XU Z, DING H, XIN F, et al. Antibacterial Activity and Possibly Made of Action of Isoquinoline-3-Carboxylic Acid[J]. Natural Product Communications, 2024. DOI:10.1177/1934578x241226562.
ISOQUINOLINE-5-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 19894 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
View Lastest Price from ISOQUINOLINE-5-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | ISOQUINOLINE-5-CARBOXYLIC ACID
27810-64-6
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-12-27 | ISOQUINOLINE-5-CARBOXYLIC ACID
27810-64-6
|
US $1.00 / KG | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- ISOQUINOLINE-5-CARBOXYLIC ACID
27810-64-6
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- ISOQUINOLINE-5-CARBOXYLIC ACID
27810-64-6
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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