Methyl 2,3-diaminobenzoate
- CAS No.
- 107582-20-7
- Chemical Name:
- Methyl 2,3-diaminobenzoate
- Synonyms
- 2,3-DIAMINOBENZOIC ACID METHYL ESTER;METHYL 2,3-DIAMINOBENZOATE;Benzoic acid, 2,3-diamino-, methyl ester;2,3-Diaminobenzoic Acid Methyl Ester Discontinued. See D416211
- CBNumber:
- CB7724743
- Molecular Formula:
- C8H10N2O2
- Molecular Weight:
- 166.18
- MDL Number:
- MFCD04038589
- MOL File:
- 107582-20-7.mol
| Product description | Number | Pack Size | Price |
| Methyl 2,3-Diaminobenzoate >98.0%(GC) | M2979 | 1g | $85 |
| Methyl 2,3-Diaminobenzoate >98.0%(GC) | M2979 | 5g | $274 |
| 2,3-Diaminobenzoic acid methyl ester | FD11827 | 10g | $350 |
| 2,3-DiaminobenzoicacidMethylEster | X8850 | 10g | $371 |
| 2,3-Diaminobenzoic acid methyl ester 95+% | 075301 | 5g | $148 |
| More product size | |||
| Melting point | 68-70°C |
|---|---|
| Boiling point | 322.6±22.0 °C(Predicted) |
| Density | 1.260±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| form | powder to crystal |
| pka | 3.02±0.10(Predicted) |
| color | Light yellow to Brown |
| InChI | InChI=1S/C8H10N2O2/c1-12-8(11)5-3-2-4-6(9)7(5)10/h2-4H,9-10H2,1H3 |
| InChIKey | BLJHLOLVEXWHFS-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC=CC(N)=C1N |
| CAS DataBase Reference | 107582-20-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| Risk Statements | 36/37/38-43 | |||||||||
| Safety Statements | 26-36/37/39-36/37 | |||||||||
| HS Code | 2921599090 | |||||||||
| NFPA 704 |
|
Methyl 2,3-diaminobenzoate price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2979 | Methyl 2,3-Diaminobenzoate >98.0%(GC) | 107582-20-7 | 1g | $85 | 2025-07-31 | Buy |
| TCI Chemical | M2979 | Methyl 2,3-Diaminobenzoate >98.0%(GC) | 107582-20-7 | 5g | $274 | 2025-07-31 | Buy |
| Biosynth Carbosynth | FD11827 | 2,3-Diaminobenzoic acid methyl ester | 107582-20-7 | 10g | $350 | 2021-12-16 | Buy |
| AK Scientific | X8850 | 2,3-DiaminobenzoicacidMethylEster | 107582-20-7 | 10g | $371 | 2021-12-16 | Buy |
| Matrix Scientific | 075301 | 2,3-Diaminobenzoic acid methyl ester 95+% | 107582-20-7 | 5g | $148 | 2021-12-16 | Buy |
Methyl 2,3-diaminobenzoate Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Anticancer Research
2,3-Diaminobenzoic acid methyl ester is a redox potential catalyst that has been shown to have anticancer activity in vitro and in vivo. It is a 5-ht4 receptor agonist, which causes an increase in the intracellular concentration of cAMP. The anticancer effect of this compound may be due to its ability to inhibit the growth of cancer cells by blocking DNA synthesis and cell division.
Synthesis
57113-91-4
107582-20-7
General procedure for the synthesis of methyl 2,3-diaminobenzoate from methyl 2-amino-3-nitrobenzoate: to a nitrogen-saturated solution of methyl 2-amino-3-nitrobenzoate (Chess GmbH, 50 g, 0.26 mol) in anhydrous ethanol (800 mL) was added palladium hydroxide (Degussa, 20% w/w carbon, 58.75% w/w water. 10g). The mixed slurry was degassed and stirred vigorously at room temperature under hydrogen (4 atm) atmosphere for 48 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under vacuum to give methyl 2,3-diaminobenzoate as a dark orange oil, which solidified to a solid after standing (43 g, 0.26 mol, 100% yield). Mass spectrometry analysis (m/z): calculated value of [M-OCH3]+ C8H10N2O2 was 135.05; measured value was 135.3.1H NMR (300 MHz, DMSO-d6) data: δ (ppm) 3.74 (s, 3H), 4.80 (br s, 1H), 6.20 (br s, 1H), 6.38 (t, 1H). 6.70 (d, 1H), 7.06 (d, 1H).
References
[1] Patent: US2006/270652, 2006, A1. Location in patent: Page/Page column 14
[2] Patent: WO2010/3048, 2010, A1. Location in patent: Page/Page column 117
[3] Patent: WO2008/157270, 2008, A1. Location in patent: Page/Page column 126
[4] Patent: EP1452528, 2004, A1. Location in patent: Page 22
[5] Patent: US2009/186879, 2009, A1. Location in patent: Page/Page column 50
Methyl 2,3-diaminobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 925 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29847 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from Methyl 2,3-diaminobenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-11-16 | Methyl 2,3-diaminobenzoate
107582-20-7
|
US $10.00 / Kg/Bag | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd | |
 |
2019-07-06 | Methyl 2,3-diaminobenzoate
107582-20-7
|
US $1.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- Methyl 2,3-diaminobenzoate
107582-20-7
- US $10.00 / Kg/Bag
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
-
- Methyl 2,3-diaminobenzoate
107582-20-7
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
