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5-BROMO-2-METHYL-1H-BENZIMIDAZOLE

CAS No.
1964-77-8
Chemical Name:
5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
Synonyms
5-BROMO-2-METHYL-1H-BENZO[D]IMIDAZOLE;6-bromo-2-methyl-1H-benzo[d]imidazole;2-Methy-5-bromobenzimidazole;5-bromo-2-methybenzimidazole;5-BROMO-2-METHYLBENZIMIDAZOLE;5-Bromo-2-methylbenzoimidazole;5-BROMO-2-METHYL-1H-BENZIMIDAZOLE;5-Bromo-2-methyl-1H-benzoimidazole;1H-BenziMidazole, 6-broMo-2-Methyl-;5-broMo-2-Methyl-1H-1,3-benzodiazole
CBNumber:
CB7733608
Molecular Formula:
C8H7BrN2
Molecular Weight:
211.06
MDL Number:
MFCD00457521
MOL File:
1964-77-8.mol
MSDS File:
SDS
Last updated:2026-05-28 03:06:48
Product description Number Pack Size Price
5-Bromo-2-methyl-1H-benzimidazole AldrichCPR ANV00243 1 g $197
5-Bromo-2-methylbenzimidazole 97% AS12187 5g $32
5-Bromo-2-methylbenzimidazole 97% AS12187 25g $74
5-Bromo-2-methylbenzimidazole 97% AS12187 100g $281
5-Bromo-2-methyl-1H-benzo[d]imidazole 119046 1.00g $82
More product size

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Properties

Melting point 214-215 °C
Boiling point 397.3±15.0 °C(Predicted)
Density 1.654±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form solid
pka 10.50±0.10(Predicted)
Appearance Light yellow to yellow Solid
InChI InChI=1S/C8H7BrN2/c1-5-10-7-3-2-6(9)4-8(7)11-5/h2-4H,1H3,(H,10,11)
InChIKey FHDFUQGJYYGLHJ-UHFFFAOYSA-N
SMILES C1(C)NC2=CC(Br)=CC=C2N=1
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich ANV00243 5-Bromo-2-methyl-1H-benzimidazole AldrichCPR 1964-77-8 1 g $197 2026-04-30 Buy
Activate Scientific AS12187 5-Bromo-2-methylbenzimidazole 97% 1964-77-8 5g $32 2026-06-04 Buy
Activate Scientific AS12187 5-Bromo-2-methylbenzimidazole 97% 1964-77-8 25g $74 2026-06-04 Buy
Activate Scientific AS12187 5-Bromo-2-methylbenzimidazole 97% 1964-77-8 100g $281 2026-06-04 Buy
Matrix Scientific 119046 5-Bromo-2-methyl-1H-benzo[d]imidazole 1964-77-8 1.00g $82 2026-05-18 Buy
Product number Packaging Price Buy
ANV00243 1 g $197 Buy
AS12187 5g $32 Buy
AS12187 25g $74 Buy
AS12187 100g $281 Buy
119046 1.00g $82 Buy

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Chemical Properties,Uses,Production

Uses

5-Bromo-2-methyl-1H-benzo[D]imidazole is a benzo[D]imidazole derivative. Benzimidazole compounds possess biological activities such as anti-HIV-1 activity, anti-tumor activity, anti-cell proliferation activity, anti-parasitic activity, anti-inflammatory activity, antioxidant activity, and anti-epileptic activity. In addition, these compounds are also used as metal ligands. Therefore, the synthesis of these compounds has attracted considerable attention from chemists.

Synthesis

Triethyl orthoacetate

78-39-7

4-Bromo-1,2-benzenediamine

1575-37-7

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE

1964-77-8

GENERAL METHOD: A mixture of 4-bromophthalimide (1.0 mmol), triethyl orthoacetate (1.2 mmol) and ZrCl4 (0.1 mmol) in 10 mL of methanol was stirred at room temperature for 3 hours. Upon completion of the reaction, the progress was monitored by TLC and the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography with an eluent ratio of petroleum ether/ethyl acetate (4:1 to 1:1, v/v) to afford the target compound 5-bromo-2-methyl-1H-benzo[D]imidazole.

References

[1] European Journal of Medicinal Chemistry, 2015, vol. 90, p. 241 - 250

1445-45-0
875-51-4
1964-77-8
Synthesis of 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE from Trimethyl orthoacetate and 4-Bromo-2-nitroaniline
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View Lastest Price from 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Bromo-2-Methyl-1H-Benzimidazole pictures 2021-07-13 5-Bromo-2-Methyl-1H-Benzimidazole
1964-77-8
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
5-Bromo-2-Methyl-1H-Benzimidazole pictures 2021-07-10 5-Bromo-2-Methyl-1H-Benzimidazole
1964-77-8
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
5-BROMO-2-METHYL-1H-BENZIMIDAZOLE pictures 2019-12-23 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
1964-77-8
$1.00 1KG 99% 200kg Career Henan Chemical Co

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Spectrum

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE 5-BROMO-2-METHYLBENZIMIDAZOLE 5-BROMO-2-METHYL-1H-BENZ(D)IMIDAZOLE 5-Bromo-2-methylbenzoimidazole 1H-BenziMidazole, 6-broMo-2-Methyl- 5-broMo-2-Methyl-1H-1,3-benzodiazole 5-Bromo-2-methyl-1H-benzoimidazole 5-bromo-2-methybenzimidazole 2-Methy-5-bromobenzimidazole 5-Bromo-2-methyl-1H-benzimidazole 5-BROMO-2-METHYL-1H-BENZO[D]IMIDAZOLE 6-bromo-2-methyl-1H-benzo[d]imidazole 1964-77-8 C8H7BrN2